Ian Lewis

ORCID: 0000-0002-6283-5287
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About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Anesthesia and Sedative Agents
  • Cardiac, Anesthesia and Surgical Outcomes
  • Airway Management and Intubation Techniques
  • Nausea and vomiting management
  • Pediatric Pain Management Techniques
  • Reproductive Biology and Fertility
  • Animal Genetics and Reproduction
  • Anesthesia and Neurotoxicity Research
  • Sarcoma Diagnosis and Treatment
  • Genetic and phenotypic traits in livestock
  • Electrolyte and hormonal disorders
  • Medical Education and Admissions
  • Lymphoma Diagnosis and Treatment
  • Viral gastroenteritis research and epidemiology
  • Health and Medical Research Impacts
  • Renal and related cancers
  • Animal Disease Management and Epidemiology
  • Gastroesophageal reflux and treatments
  • Congenital Diaphragmatic Hernia Studies
  • Global Health Workforce Issues
  • Hemodynamic Monitoring and Therapy
  • Animal Behavior and Welfare Studies
  • Sperm and Testicular Function
  • Adrenal and Paraganglionic Tumors

Hartpury University
2024-2025

University Hospital of Wales
2025

Anglia Ruskin University
2024

Writtle University College
2024

Monash Medical Centre
1994-2019

Novo Nordisk (Denmark)
2019

University of Michigan
1990-2013

C. S. Mott Children's Hospital
1993-2007

Royal Victoria Infirmary
2006

Southampton General Hospital
1990-2003

The problems of sustaining placenta formation in embryos produced by nuclear transfer have emphasized the need for basic knowledge about epiblast and gastrulation bovine embryos. aims this study were to define stages post-hatching embryonic development analyse functional mechanisms germ-layer formation. Embryos developed vivo collected after slaughter from superovulated cows on days 9, 11, 14 21 insemination processed transmission electron microscopy (n = 26) or immunohistochemistry 27)...

10.1530/rep.0.1250607 article EN Reproduction 2003-04-01

The rectus sheath block has been used with success for postoperative analgesia in adults. This paper reviews the anatomy of sheath, and presents our initial experience using to provide intra- children having repair umbilical paraumbilical hernia. appears be a useful technique children, particularly paediatric day-cases surgery.

10.1046/j.1460-9592.1996.d01-24.x article EN Pediatric Anesthesia 1996-12-01

A prospective, randomized, double-blind study was conducted to examine the effect of a propofol infusion on incidence postoperative emesis in children undergoing outpatient strabismus surgery. Seventy-eight children, aged 3-12 yr, were allocated randomly receive either nitrous oxide and halothane or for maintenance anesthesia. The overall vomiting during first 24 h 64% those receiving 41% infusion; this difference statistically significant (P < 0.05). In who received no opioids...

10.1213/00000539-199304000-00013 article EN Anesthesia & Analgesia 1993-04-01

Abstract Background Pediatric hematology–oncology (PHO) patients are at significant risk for developing central line‐associated bloodstream infections (CLA‐BSIs) due to their prolonged dependence on such catheters. Effective strategies eliminate these preventable urgently needed. In this study, we investigated the implementation of bundled line maintenance practices and effect hospital‐acquired CLA‐BSIs. Materials Methods CLA‐BSI rates were analyzed within a single‐institution's PHO unit...

10.1002/pbc.24187 article EN Pediatric Blood & Cancer 2012-04-22

To what extent sildenafil, a selective inhibitor of the type-5 phosphodiesterase modulates systemic redox status and cerebrovascular function during acute exposure to hypoxia remains unknown. address this, 12 healthy males (aged 24 ± 3 y) participated in randomized, placebo-controlled crossover study involving both normoxia (60 min) (FiO2 = 0.14), followed by oral administration 50 mg sildenafil placebo (double-blinded). Venous blood was sampled for ascorbate radical (A•-: electron...

10.1177/0271678x251313747 article EN Journal of Cerebral Blood Flow & Metabolism 2025-01-25

Abstract One of the most common barriers we see in human medicine is a fear needles, and this mainly related to experience pain. Needles are routinely used livestock production as main route deliver vaccines consideration should be made towards pain induced livestock. Livestock essential meet growing increase population with pork being second consumed meat product globally. The importance disease prevention has been stated, however, welfare at forefront for consumers stakeholders. Research...

10.1079/abwcases.2025.0009 article EN Animal Behaviour and Welfare Cases 2025-03-28

Summary Conflicting reports regarding the hazards of anaesthesia in children presenting for surgery with an upper respiratory tract infection have appeared literature. In present study 130 undergoing general face mask myringotomy and grommet insertion were graded as having either acute or recent asymptomatic according to predetermined clinical symptoms signs. The severity related complications scored during induction, emergence recovery. peripheral oxygen saturation was recorded emergence,...

10.1111/j.1365-2044.1992.tb02389.x article EN Anaesthesia 1992-08-01

The role of nitrous oxide anesthesia in causing postoperative vomiting (POV) was studied 60 children undergoing outpatient tonsillectomy and adenoidectomy.In this controlled, randomized, double-blind investigation, induced by inhalation a volatile anesthetic both groups. nonnitrous group received no oxide, even during induction anesthesia. Designated nurses the postanesthesia care unit (PACU) who were blinded to technique evaluated incidence severity patient's emetic symptoms, PACU as well...

10.1097/00000539-199502000-00005 article EN Anesthesia & Analgesia 1995-02-01

Summary Background: Few articles have addressed the issue of child who refuses anesthesia or sedation for surgery. A survey members Society Pediatric Anesthesia in USA was conducted regarding their experience with pediatric refusal and assent Methods: Structured response open‐end questions were used a confidential postal to assess following: details cancellations, use of, attitudes to, physical restraint at induction, premedication, management hypothetical case individual techniques...

10.1111/j.1460-9592.2007.02331.x article EN Pediatric Anesthesia 2007-09-08

Summary Background Nearly 20% of anesthesia‐related pediatric cardiopulmonary arrests ( CPA s) occur during emergence or recovery. The aims this study were to describe (i) the nature postanesthesia care unit PACU ) and subsequent outcomes (ii) factors associated with mortality. Methods Cardiopulmonary Arrests occurring in children (&lt;18 years) identified from American Heart Association Get With Guidelines ® ‐Resuscitation, multicenter registry. Demographics, underlying conditions, cause(s)...

10.1111/pan.12154 article EN Pediatric Anesthesia 2013-04-01

10.1093/bja/73.2.244 article EN publisher-specific-oa British Journal of Anaesthesia 1994-08-01

Abstract In-farm livestock production vaccinations are commonly delivered intramuscularly using needles. While there alternative strategies these have been subject to little attention and limited commercialisation. One such is needle-free vaccines studies focused on the immune response few addressed welfare implications. This study aims compare impact of intradermal vaccination intramuscular injection in terms piglets. A total 179 piglets were divided into two treatments: delivery a vaccine....

10.1017/awf.2024.53 article EN cc-by-nc-nd Animal Welfare 2024-01-01

We have examined the in vitro and vivo development of cloned embryos produced by incorporation fetal fibroblast into matured enucleated cow oocytes direct injection fusion. For injection, nuclei were either mechanically isolated using microinjection needle or chemically treatment with NP-40 lysis buffer. Fetal fibroblasts serum starved treated calcium ionophore before to induce chromatin condensation. A range 8% 16% successfully injected developed blastocysts culture a total nine pregnancies...

10.1089/152045500436078 article EN Cloning 2000-10-08

Summary A prospective, randomized, double‐blind study was conducted to determine whether cooled intravenous propofol reduces the incidence of pain on induction anaesthesia in children. Seventy patients aged 3–10 years, ASA I or II, were randomized receive 1% plus 0.05% lidocaine either at room temperature (20–23°C) 4C. Pain assessed by a blinded observer using behavioural scale. Data from 69 analysed. The 9/34 (26%, 95% confidence intervals 11–41%) injectate group and 5/35 (14%, 3–26%) cold...

10.1046/j.1460-9592.2000.00461.x article EN Pediatric Anesthesia 2000-02-01

The extensive use of embryo technologies has emphasized the need for assessing quality by morphological techniques, such as transmission electron microscopy, immunocytochemistry confocal laser scanning microscopy and fluorescence in situ hybridization. By a combination these it been possible to demonstrate: (i) that rRNA gene activation, monitored embryonic nucleolar development, is comparable bovine embryos developed vivo produced vitro, whereas reconstructed nuclear transfer may be...

10.1530/biosciprocs.5.009 article EN Bioscientifica Proceedings 2019-04-05
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