A5070134639- Paraoxonase enzyme and polymorphisms
- Medical and Biological Ozone Research
- Traditional Chinese Medicine Analysis
- Cynara cardunculus studies
- Blood Coagulation and Thrombosis Mechanisms
- Radiopharmaceutical Chemistry and Applications
- Drug-Induced Hepatotoxicity and Protection
- Cancer Treatment and Pharmacology
- Connexins and lens biology
- Liver Disease and Transplantation
- Bone health and osteoporosis research
- Bone health and treatments
- Vitamin C and Antioxidants Research
- Bee Products Chemical Analysis
- Omental and Epiploic Conditions
- Atherosclerosis and Cardiovascular Diseases
- Childhood Cancer Survivors' Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Vitamin K Research Studies
- Liver Disease Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- Occupational and environmental lung diseases
- Inflammasome and immune disorders
- Blood properties and coagulation
- Essential Oils and Antimicrobial Activity
Eskişehir Osmangazi University
2005-2020
Cynara scolymus is a pharmacologically important medicinal plant containing phenolic acids and flavonoids. Experimental studies indicate antioxidant hepatoprotective effects of C. but there have been no about therapeutic liver diseases yet. In the present study, hepatocurative leaf extract on carbon tetrachloride (CCl4)-induced oxidative stress hepatic injury in rats were investigated by serum enzyme levels, indicator (malondialdehyde-MDA), endogenous antioxidants, DNA fragmentation, p53,...
Salvia officinalis, which has a high phenolic acid and flavonoid content, is powerful antioxidant anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases could cause damage by means oxidative stress. The aim this study was to investigate activity S. officinalis formed lipopolysaccharide (LPS)-induced experimental inflammation model. Four- five-month-old 42 female Wistar albino rats were divided into six groups. Three groups administered...
Propolis is a natural bee product, and it has many effects, including antioxidant, anti-inflammatory, antihepatotoxic, anticancer activity. In this study, we aimed to explore the potential in vivo antiapoptotic properties of propolis extract on lipopolysaccharide (LPS)-induced inflammation rats. Forty-two, 3- 4-month-old male Sprague Dawley rats were used six groups. LPS (1 mg/kg) was administered intraperitoneally inflammation, + propolis30, inflammation+propolis90 Thirty milligram/kilogram...
The aim of this study is to examine the therapeutic effects Olea europaea L. leaf extract on carbon tetrachloride (CCl4)-induced liver damage in rats. In experiments, 3- 4-month-old 28 male Sprague-Dawley rats were divided into four groups: control, O. extract, CCl4, and curative. CCl4 curative groups received (0.2 mL/kg) intraperitoneally for 10 days form hepatic injury. (80 mg/kg) was given orally group dissolved distilled water following 14 days. Hepatic antioxidant enzyme levels, p53,...
Essential hypertension (EH) is defined as a worldwide public health problem and one of the important risk factors for development human coronary artery disease. Increased peripheral arterial resistance distinguishing characteristics EH. The extracellular deposition calcium in wall vascular calcification, which results aortic stiffness elevation blood pressure. Regulation calcification physiologically limited by γ-carboxylated proteins that regulate mineralization. Any deficiencies related to...
Oxidative stress is a potential mechanism involved in the pathogenesis of iron deficiency anaemia (IDA). Although tendency for hypercoagulability has been reported IDA, its underlying yet to be elucidated. This study investigated probable relationship between oxidative and children with IDA. included 57 diagnosed IDA (IDA group) October 2016 2017 addition 48 healthy (control group). The maximum clot firmness (MCF) index, formation time (CFT) which are indicators rotational thromboelastometry...
BACKGROUND: Malignant pleural mesothelioma (MPM) is the most common cancer in pleura and highly aggressive with a very poor prognosis. Asbestos, known as carcinogenic mineral fiber structures, main cause of MPM formation. Exposure to asbestos causes an increase reactive oxygen species, deficiency antioxidant enzyme levels, DNA damage. As result pathogenesis, all these changes pulmonary fibrosis, diseases, malignancies. The endogenous paraoxonase-1 (PON-1) calcium-dependent esterase involved...