Shichang Cai

ORCID: 0000-0002-6320-6423
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About
Contact & Profiles
Research Areas
  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Apelin-related biomedical research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Circadian rhythm and melatonin
  • Analytical Chemistry and Chromatography
  • Pancreatic function and diabetes
  • Receptor Mechanisms and Signaling
  • Inflammasome and immune disorders
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Neurogenesis and neuroplasticity mechanisms
  • Paraoxonase enzyme and polymorphisms
  • Hemoglobin structure and function
  • Genomics, phytochemicals, and oxidative stress
  • Neurological Disorders and Treatments
  • Lipid metabolism and disorders
  • Heme Oxygenase-1 and Carbon Monoxide
  • Sphingolipid Metabolism and Signaling
  • Dietary Effects on Health
  • Retinopathy of Prematurity Studies
  • Autophagy in Disease and Therapy
  • Nerve injury and regeneration
  • Metabolism, Diabetes, and Cancer

Hunan University
2016-2025

Huaihua University
2013

Currently, VR technology is constantly developing and widely applied in the field of medical education. Many experiments courses have evolved from simple animated demonstrations to virtual simulation experiments. The current lack intuitive clarity ease operation teaching human anatomy a common problem. 3D anatomical structure model has advantages three-dimensional highly simulated teaching, which can effectively reproduce entity information tissues organs. This article introduces basic...

10.1117/12.3045790 article EN 2025-01-16

Melatonin (Mel) and its receptors are promising for glycaemic control in patients with type 2 diabetes mellitus (T2DM) complications, but there is significant heterogeneity among studies. This study aims to investigate the effects of Mel receptor agonist Neu-P11 on glucose metabolism, immunity, islet function T2DM rats.In this study, SD rats were treated a high-fat diet streptozotocin (STZ) establish model. The oxidase method was used measure blood levels. Glucose insulin tolerance tests...

10.5603/ep.a2021.0084 article EN cc-by-nc-nd Endokrynologia Polska 2021-10-14

It is generally accepted that a major risk factor of type 2 diabetes mellitus (T2DM) insulin resistance and often associated with obesity [1]. Apelin (expressed in adipose tissue) appears as beneficial adipokine anti-diabetic antiobesity properties [2]. Clock large complex gene encoding novel member the basic helix-loop-helix/ Per-ARNT-Sim protein family transcription factors. Circadian clocks can regulate metabolic homeostasis clock disruption leads to syndrome [3]. Melatonin (Mel) an...

10.1093/abbs/gmt077 article EN Acta Biochimica et Biophysica Sinica 2013-08-20

The study aimed to explore the effects of treatment with black bamboo rhizome extracts on learning and memory determine underlying mechanisms in rats cerebral ischaemia-reperfusion injury.Sprague-Dawley were randomly divided into following four groups: control, middle artery occlusion (MCAO), low-dose drug, high-dose drug groups. Rats underwent MCAO using a suture method before treatment. Then, neurological impairment was assessed Longa scoring method, triphenyl tetrazolium chloride staining...

10.2147/ndt.s314162 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2021-07-01

Ischaemic stroke is a common condition leading to human disability and death. Previous studies have shown that oleanolic acid (OA) ameliorates oxidative injury cerebral ischaemic damage, miR-186-5p verified be elevated in serum from patients. Herein, we investigated whether OA regulates expression control neuroglobin (Ngb) levels, thereby inhibiting neuronal pyroptosis stroke. Three concentrations of (0.5, 2, or 8 μM) were added primary hippocampal neurons subjected oxygen-glucose...

10.5607/en21006 article EN Experimental Neurobiology 2021-12-31

10.3724/sp.j.1008.2012.01324 article EN Academic Journal of Second Military Medical University 2013-06-27
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