Continuous glucose monitors are crucial for diabetes management, but invasive sampling, signal drift and frequent calibrations restrict their widespread usage. Microneedle sensors emerging as a minimally-invasive platform real-time monitoring of clinical parameters in interstitial fluid. Herein, painless flexible microneedle sensing patch is constructed by mechanically-strong base thin layer fluorescent hydrogel sensor on-site, accurate, continuous monitoring. The Förster resonance energy...

Diabetes and pancreatic cancer (PC) may concurrently affect the same individual. In such patients, receiving both anti-diabetic drugs anti-tumor therapy is indispensable to control disease progression. recent years, immunotherapy has brought significant advances in treatment. However, as one of most common classes antidiabetic medications, role sulfonylureas (SUs) PC remains largely unknown, their clinical application still limited. A murine syngeneic Pan02 model was established assess...

Abstract Metamaterials with local resonance show promising application prospects in low-frequency vibration attenuation. However, the drawback of narrow band gap, such potential is greatly limited. In order to broaden resonant a semi-active graded magnetorheological elastomer (MRE) metamaterial sandwich beam (GMREMSB) real-time tunable stiffness was proposed and investigated this study. For theoretical calculation, mass-spring model established for GMREMSB. Then calculated gap...

This study investigates the impact of political connection and information asymmetry on investment efficiency firms in China. paper employs a panel data regression analysis dataset comprising 4307 observations for listed companies from 2008 to 2015. The results indicate that if taken alone, neither nor affects firms’ efficiency. However, interactive effect both significantly reduces this help investors understand forces lead Chinese deviate optimal decisions.

Abstract A three‐dimensional hierarchical CdO nanostructure with a novel bio‐inspired morphology is reported. The field emission scanning electronic microscopy, transmission electron microscopy and X‐ray diffractometer were employed to characterize the as‐prepared samples. In gas‐sensing measurements, acetone diethyl ether as target gases investigate cataluminescence (CTL) sensing properties of nanostructure. results show that as‐fabricated exhibited outstanding CTL such stable intensity,...

Incremental sheet metal forming characterized as increased flexibility and local plastic deformation is well suitable for low-production-run manufacturing a new sample trial production of complex shapes. Thickness thinning still an obstacle to the application incremental forming. In this study, novel mathematical algorithm based on non-uniform rational B-spline (NURBS) surface was proposed implemented which focuses predicting calculating final thickness arbitrary parts in order evaluate...

Epoxy resin is widely used in the support, insulation, and packaging components of electrical equipment owing to their excellent thermal, mechanical properties.However, epoxy-resin insulation often suffers from thermal stresses under extreme environmental conditions a compact design, which can induce tree degradation failure equipment.In this study, photoelastic method employed investigate thermal-mechanical coupling stress dependence treeing behavior epoxy resin.Typical growth morphology...

Abstract A novel and sensitive gas sensor was developed for the determination of benzene based on its cataluminescence (CTL) by oxidation in air surface hollow magnesium silicate spheres. Luminescence characteristics optimum conditions were investigated. Results indicated that as‐prepared spheres exhibited outstanding CTL properties such as stable intensity, high signal/noise values, short response recovery times. Under optimized conditions, a broad linear range 1–4500 ppm, with correlation...

Based on particle swarm optimization (PSO) algorithm and its power system reactive method to in-depth study research proposed a new hybrid (HPSO).Algorithm combines the differential evolution simulated annealing algorithm, in searching optimal except for tracking individual global, tracks produced by information difference of three value.At same time, when search space one dimension speed lower than setting value will be re initialized dimensional velocity mutation.For crossover mutation...

Anhydride-cured bisphenol-A epoxy resin is widely used in the support, insulation, and packaging components of electrical electronic devices due to its excellent comprehensive performance. The dielectric properties anhydride-cured depend on crosslinking structure, which not only related matrix, curing agent, additives but also greatly affected by conditions process. In this study, high-temperature diglycidyl ether bisphenol A (DGEBA)/methyl hexahydrophthalic anhydride...

This paper proposes a novel full kinematic incremental forming process, called three opposite point (TOPIF), in which one pair of main tools and two pairs auxiliary as the supporting dynamic die are utilized to perform components along predefined path. Compared conventional sheet (KISF) SPIF, process can effectively control local deformation, improve geometric accuracy increase ability form complex curved surface. The deformation analysis on TOPIF is key deformation. A strain distributions...

Spontaneous combustion occurred many times in the goaf of E12606 Fully Mechanized Working Face Cuijiazai Coal Mine. For reinforcing fire prevention and extinguishing management, thermocouple thermometry bundle tube monitoring system had been laid working face. Through analyzing measurement result (temperature oxygen change rule), distribution regularities three zones spontaneous working-face propulsion speed determined for goaf. This research provides technical support Mine to prevent...

Abstract Acoustic metamaterials are capable of generating bandgaps at specific frequency ranges, which makes them have good applications in the field vibration isolation. The can be further broadened with active control, nonlinear components and graded structures, such as: controllable stiffness by magnetorheological elastomer (MRE) stiffness. However, current approaches to reducing limitations. Both reduction structural increase mass will reduce overall stability acoustic metamaterial. In...

Trimeresurus stejnegeri (T.s) accounts for most snakebites in southern China, which always leads to coagulation dysfunction. Coagulopathy due venom is widely considered be a characteristic phenomenon of the DIC-like syndrome. It vitally important first-line clinicians improve this condition as soon possible. However, clinical factors associated with function has not been well characterized yet.Patients bitten by vipers were admitted Emergency Department hospital Shenzhen, from 2021 2022 and...