A5078010582- Long-Term Effects of COVID-19
- Telemedicine and Telehealth Implementation
- Burn Injury Management and Outcomes
- Cardiac Arrest and Resuscitation
- Healthcare Systems and Technology
- COVID-19 Clinical Research Studies
- Disaster Response and Management
- COVID-19 and Mental Health
- Spine and Intervertebral Disc Pathology
- Child and Adolescent Psychosocial and Emotional Development
- Protein Degradation and Inhibitors
- Child and Adolescent Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Multiple Myeloma Research and Treatments
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Infective Endocarditis Diagnosis and Management
- Management of metastatic bone disease
- Dermatology and Skin Diseases
- Trauma and Emergency Care Studies
- Breastfeeding Practices and Influences
- Digital Mental Health Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Bacterial Identification and Susceptibility Testing
- Thermal Regulation in Medicine
University of California, Davis
2020-2025
University of California Davis Medical Center
2021-2025
New York University
1991-2023
National Center for Advancing Translational Sciences
2022-2023
Shriners Hospitals for Children - Northern California
2023
California State University, Sacramento
2023
University of Louisville
2023
University Medical Center
2023
National Institutes of Health
2022
Cornell University
1992
Abstract Background Therapeutic drug monitoring (TDM) is often recommended with triazole antifungals. Isavuconazole TDM currently not uniformly due to its high oral bioavailability, modest drug-drug interactions, and linear pharmacokinetics; however, an assessment of serum levels toxicity has been reported. This study aimed explore the exposure-toxicity relationship for isavuconazole. The primary outcome was threshold isavuconazole level most predictive toxicity. Secondary outcomes included...
This report is concerned with a) the degree of recall mental content from Stage 4 night terrors; b) classification types recalled; c) problem whether recalled occurred just before, during, or after explosive onset terror episode, that is, it was related to "prearousal" "postarousal" events; and d) implications above findings for nature triggering mechanism terror. A mean 58 per cent terrors found, approximating reported elicited nonanxious 3-4 awakenings in normal subjects. As inferred...
This cohort study uses the Vizient Clinical Data Base to compare postoperative in-hospital morbidity and mortality of surgical patients with COVID-19 infection without infection.
To investigate demographic disparities in failed episodes of telemedicine utilization. The primary hypothesis was that certain groups, including older adults and specific racial or ethnic would experience disparate amounts video visits. A retrospective review conducted using electronic health record-integrated scheduled telehealth visit telemetry data gathered for all visits at a California academic center from September 1, 2020, to November 30, 2020. For each visit, we collected...
Objectives: ABRUPT was a prospective, noninterventional, observational study of resuscitation practices at 21 burn centers. The primary goal to examine with albumin or crystalloids alone, design future prospective randomized trial. Summary Background Data: No modern has determined whether use colloids for acute resuscitation. Methods: Patients ≥18 years burns ≥ 20% total body surface area (TBSA) had hourly documentation parameters 48 hours. received either alone supplemented crystalloid...
Guideline-directed medical therapy (GDMT) is the recommended treatment for heart failure with reduced ejection fraction (HFrEF). However, implementation remains limited, suboptimal use and dosing. The study aimed to assess feasibility effect of a remote monitoring titration program on GDMT implementation.HFrEF patients were randomly assigned receive either usual care or quality-improvement intervention. intervention group used wireless devices transmit rate, blood pressure, weight data...
This study examined cardiac and respiratory activity in panic disorder patients healthy comparison subjects during sleep, when the effects of anxious cognition expectancy set are minimized.Heart rate, end-tidal PCO2, oxygen saturation were recorded for 11 12 before sleep after infusions sodium lactate a saline control.Panic had higher saturations than onset stages 0 2 any infusions. The two groups did not differ on other variables heart rate. Panic responded to stage 3-4 with greater...
Asynchronous telepsychiatry (ATP; delayed-time) consultations are a novel form of psychiatric consultation in primary care settings. Longitudinal studies comparing clinical outcomes for ATP with synchronous (STP) lacking.
This study aimed to characterize the role of sex and pubertal markers in reward motivation behavior neural processing early adolescence. We used baseline two-year follow-up data from Adolescent Brain Cognitive DevelopmentSM (15844 observations; 52% boys; age 9–13). Pubertal development was measured with parent-reported Development Scale, DHEA, testosterone, estradiol levels. Reward at anticipation feedback stages were assessed Monetary Incentive Delay task. Boys had higher than girls,...
Examine the impact of vaccination status on hospital cost and course for patients admitted with COVID-19 infection.Retrospective cohort study characterizing vaccinated unvaccinated individuals hospitalized between April 2021 to January 2022.Large academic medical center.Patients were included if they greater than 18 years old, fully or against COVID-19, infection.437 consecutively infection met inclusion criteria. Of these, 79 excluded unknown partial status, transfer from an outside...
Protein extravasation and airway conductance (SGaw) were examined in awake guinea pigs exposed to inhaled endotoxin or saline for three hours. A significant increase protein (as estimated by the leakage of bound Evans blue dye) was seen conducting airways animals compared with animals. Mean dye significantly increased one threefold mainstem hilar bronchi These changes accompanied decrements pulmonary function an influx polymorphonuclear leucocytes into wall. The SGaw decreased 60-90 minutes...
High-quality cardiopulmonary resuscitation (CPR) is foundational to all resuscitative efforts. Spaced practice improves learners' skill retention. We evaluated the implementation of a quarterly CPR curriculum and skills training program for dedicated chest compressor team improve quality performed during in-hospital cardiac arrest (IHCA) events its impact on patient survival event. Baseline observations performance within hospital were collected in October 2018. The was implemented November...
Abstract Objective Alarming rates of anxiety and burnout in pre-clinical health profession trainees are now challenged by additional COVID-19 stressors. This study explored COVID-related stressors among first-year medical, physician assistant, nurse practitioner, veterinary medical students. The authors examined associations between resilience, news monitoring, COVID stress. Methods Students completed an online questionnaire that included the Brief Resilience Scale at their matriculation...
Retrospective cohort.Compare the performance of and provide cutoff values for commonly used prognostic models spinal metastases, including Revised Tokuhashi, Tomita, Modified Bauer, New England Spinal Metastases Score (NESMS), Skeletal Oncology Research Group model, at three- six-month postoperative time points.Surgery may be recommended patients with metastases causing fracture, instability, pain, and/or neurological compromise. However, less than three to six months projected survival are...
The ability to detect bacteriuria in dogs with a point-of-care test might improve medical care and antimicrobial stewardship.A rapid immunoassay (RIA; RapidBac) will provide acceptable sensitivity specificity for diagnosis of bacteriuria.Forty-four client-owned clinical indication urinalysis aerobic bacterial urine culture.Prospective study. Urine, collected by cystocentesis, was submitted culture at diagnostic laboratory. Owners completed an enrollment questionnaire regarding their dogs'...