A5056047939- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Pregnancy and Medication Impact
- Fetal and Pediatric Neurological Disorders
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Reproductive System and Pregnancy
- Cardiovascular Issues in Pregnancy
- Congenital Heart Disease Studies
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Parvovirus B19 Infection Studies
- Ectopic Pregnancy Diagnosis and Management
- Systemic Lupus Erythematosus Research
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Biomarkers in Disease Mechanisms
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Tracheal and airway disorders
- Gestational Trophoblastic Disease Studies
- Urological Disorders and Treatments
- Neonatal Respiratory Health Research
- Assisted Reproductive Technology and Twin Pregnancy
Istanbul University
2015-2025
Istanbul University-Cerrahpaşa
2016-2025
Lithuanian University of Health Sciences
2021
Australian National University
2021
The University of Adelaide
2021
Bendigo Health
2021
Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
2017
İstanbul Eğitim ve Araştırma Hastanesi
2015
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2015
Istanbul Medeniyet University
2015
We aimed to evaluate the utility of shear wave elastography (SWE) for assessing placenta in preeclampsia disease.A total 50 pregnant women second or third trimester (23 patients and 27 healthy control subjects) were enrolled study. Obstetrical grayscale Doppler ultrasonography, SWE findings placenta, prenatal/postnatal clinical data analyzed best cutoff value which represents diagnosis was determined. Sensitivity, specificity, positive predictive (PPV), negative (NPV), diagnostic accuracy...
Background. To determine the plasma concentrations of placental growth factor (PLGF), vascular endothelial (VEGF), transforming factor‐β 1 (TGF‐β ), soluble tumor necrosis α receptor (sTNFp55), interleukin‐2 (IL‐2R), and interleukins 6 10 (IL‐6, IL‐10) in normotensive preeclamptic women, to evaluate correlations between these cytokines diastolic blood pressure fibronectin levels. Methods. A prospective case–control study. Thirty‐five women with preeclampsia were compared 34 healthy...
<i>Background/Aims:</i> To evaluate the incidence of placental abnormalities, cord plasma erythropoietin (EPO) levels and nucleated red blood cell (NRBC) counts, maternal malondialdehyde (MDA) vascular endothelial growth factor (VEGF) in women with gestational diabetes mellitus (GDM) nondiabetic controls. <i>Methods:</i> Twenty-two GDM, diagnosed according to current criteria American Diabetes Association, were compared 22 Maternal samples obtained from all pregnant...
The aim of the study is to investigate plasma and placental levels malondialdehyde, glutathione superoxide dismutase in normotensive pre-eclamptic pregnancies. Peripheral venous blood samples were collected before labour (35·3 - 1·1 34·2 3·4 weeks for pre-eclamptic, respectively) tissues was obtained after delivery from 34 pre-eclampsia 33 mean malondialdehyde significantly higher, lower compared with patients ( P < 0·01). increased, decreased increments diastolic pressure. As a conclusion...
Abstract Asphyxiating thoracic dystrophy‐Jeune syndrome (JS) is a rare autosomal recessive disease characterized by small thorax and short limb dwarfism. Besides the clinical variability, prognosis also differs greatly among patients. Pulmonary involvement predominant in some cases whereas renal much more evident others. We aimed to investigate variability 13 patients with JS from 11 families. Two of them, who had been diagnosed prenatal period were assessed autopsy findings. All bell‐shaped...
Abstract Background Sirtuins and FoxO1 are reported to be important in the pathophysiology of preeclampsia. This study aimed investigate whether serum SIRT2 concentrations differ between preeclampsia normal pregnancy also compare these markers early- late-onset Methods cross-sectional was conducted on 27 women with early-onset preeclampsia, 26 healthy normotensive pregnant controls. Maternal levels were measured use an enzyme-linked immunosorbent assay kit. Results The mean maternal...
Preeclampsia is one of the most frequent complications pregnancy, however, little known about its etiology. The objective this study was to investigate association oxidized low-density lipoprotein (oxLDL) and paraoxonase (PON1) activity in women with either preeclampsia or normotensive (NT) pregnancy. groups included 41 pregnant 33 women. In all patients maternal serum total cholesterol (TC), high-density (HDL), (LDL), triglycerides (TGs) were measured using enzymatic methods. Serum PON1...
To evaluate placental elasticty in women with gestational diabetes mellitus (GDM) and non-diabetic controls. Thirty-three pregnant GDM according to the current criteria of American Diabetes Association 43 healthy who were admitted antenatal clinic recruited for this case–control study. Elasticity values both peripheral central parts placentas patients groups determined by shear wave elastography (SWE) imaging. Mean elasticity part significantly higher pregnancies (p < 0.001). No difference...
To determine the correlation between placental bed biopsy findings, and blood levels of vascular cell adhesion molecule (VCAM-1) fibronectin in pre-eclampsia/eclampsia, to evaluate relationship these variables severity disease.A prospective case-control study.Department Obstetrics Gynaecology, Cerrahpasa Medical Faculty, Istanbul.Thirty-five women with pre-eclampsia/eclampsia were compared 25 healthy uncomplicated pregnancies. Twenty-one biopsies from pre-eclamptic pregnancies 17 normal...
We present a retrospective review of 228 pre-term premature rupture membranes (PPROM) singleton pregnancies followed-up in our clinic between 1996 and 2005. The most common neonatal morbidities PPROM cases are respiratory distress syndrome (RDS), sepsis intraventricular haemorrhage (IVH). route delivery does not affect newborn intensive care unit (NICU) requirements, perinatal asphyxia, IVH rates cases. NICU PPV RDS, increase if the Apgar score is < 5. Neonatal morbidity mortality as latent...
The aim of the study was to investigate peripheral blood platelets, neutrophils and lymphocytes counts in women with preterm premature rupture membranes (PPROM) threatened labour (TPL) compared gestation-matched controls order learn how they change. This conducted on 60 PPROM, 50 TPL 47 healthy pregnant women. Laboratory parameters (including complete count, C-reactive protein (CRP)) all participants were recorded. neutrophil-to-lymphocyte ratio (NLR) values significantly higher PPROM group...
The aim of the present study is to investigate whether alterations in serum levels apelin and YKL-40 differ between early late onset pre-eclampsia there a correlation women who subsequently develop pre-eclampsia.A total number 80 pregnant women, 40 with normal pregnancy pre-eclampsia, were included study. Both pre-eclamptic subjects subdivided into two groups. Serum concentrations measured.Mean maternal both lower developed (87.45 ± 3.07 versus 103.40 4.29) or (96.43 4.06 99.87 3.63) than...
The aim of this study was to describe maternal and fetal characteristics associated with intrahepatic cholestasis pregnancy (ICP) determine clinical biochemical predictors complications. A total 89 singleton pregnancies ICP were analysed, retrospectively. All data concerning laboratory results, symptom onset time, treatment response, delivery time infant information recorded in the protocol. mean gestational age at diagnosis 32.6 ± 3.4 weeks; 36.8 1.9 weeks. Binary logistic regression...