- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Pregnancy and Medication Impact
- Cancer Risks and Factors
- Systemic Lupus Erythematosus Research
- Prenatal Screening and Diagnostics
- Cardiovascular Issues in Pregnancy
- Fetal and Pediatric Neurological Disorders
- Reproductive System and Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Pediatric Hepatobiliary Diseases and Treatments
- Gestational Diabetes Research and Management
- Congenital Heart Disease Studies
- Childhood Cancer Survivors' Quality of Life
- Vascular Malformations and Hemangiomas
- Parvovirus B19 Infection Studies
- Congenital Anomalies and Fetal Surgery
- Maternal and Perinatal Health Interventions
- Urological Disorders and Treatments
- Maternal and fetal healthcare
- Gynecological conditions and treatments
- COVID-19 Impact on Reproduction
- Ultrasound Imaging and Elastography
Istanbul University-Cerrahpaşa
2015-2025
Istanbul University
2015-2025
Ümraniye Eğitim ve Araştırma Hastanesi
2017-2019
Zeynep Kamil Hospital
2019
Sağlık Bilimleri Üniversitesi
2017
Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
2017
Zübeyde Hanim Maternity Hospital
2016
To evaluate placental elasticty in women with gestational diabetes mellitus (GDM) and non-diabetic controls. Thirty-three pregnant GDM according to the current criteria of American Diabetes Association 43 healthy who were admitted antenatal clinic recruited for this case–control study. Elasticity values both peripheral central parts placentas patients groups determined by shear wave elastography (SWE) imaging. Mean elasticity part significantly higher pregnancies (p < 0.001). No difference...
Abstract Background Sirtuins and FoxO1 are reported to be important in the pathophysiology of preeclampsia. This study aimed investigate whether serum SIRT2 concentrations differ between preeclampsia normal pregnancy also compare these markers early- late-onset Methods cross-sectional was conducted on 27 women with early-onset preeclampsia, 26 healthy normotensive pregnant controls. Maternal levels were measured use an enzyme-linked immunosorbent assay kit. Results The mean maternal...
ABSTRACT Purpose To construct nomograms for both sides of the fetal fornix–hippocampus complex (FHC) length and hippocampus height between 18 + 0 23 6 weeks gestation using two‐dimensional sonography. Additionally, we evaluated effects laterality, sex, maternal iron deficiency anemia on these measurements. Methods This was a prospective cross‐sectional study 223 singleton pregnancies gestation. The FHC were measured in parasagittal cranial plane fetus by 2D ultrasonography. Measurements from...
The aim of the study was to investigate peripheral blood platelets, neutrophils and lymphocytes counts in women with preterm premature rupture membranes (PPROM) threatened labour (TPL) compared gestation-matched controls order learn how they change. This conducted on 60 PPROM, 50 TPL 47 healthy pregnant women. Laboratory parameters (including complete count, C-reactive protein (CRP)) all participants were recorded. neutrophil-to-lymphocyte ratio (NLR) values significantly higher PPROM group...
Objective: To compare the fetal modified myocardial performance index (Mod-MPI) in appropriately grown, early (EO) and late onset (LO) growth restricted (FGR) fetuses to assess its prognostic significance for adverse perinatal outcome.Study design: In a prospective case-control study, Mod-MPI was performed 22 51 with EO LO-FGR fetuses, respectively. values of FGR were compared against gestation-matched controls (34 EO-, 32 LO-FGR, respectively). Correlation testing related poor outcomes...
Objective: To determine the serum levels of HIF-1 α, progranulin, and syndecan-1 in preeclampsia (PE) normal pregnancy, to compare whether these markers demonstrate any difference between early-onset PE (EO-PE) late-onset (LO-PE).Methods: This cross-sectional study was conducted on 27 women with EO-PE, LO-PE, 26 healthy normotensive pregnant controls matched for gestational age. Maternal were measured use an enzyme-linked immunosorbent assay kit.Results: Statistical analysis revealed...
Abstract Purpose To assess the incidence of associated structural anomalies, chromosomal/genetic abnormalities, infections, and perinatal outcomes fetuses with ventriculomegaly (VM), also to evaluate role fetal magnetic resonance imaging (MRI) in detecting intracranial anomalies. Methods Retrospective cohort study 149 prenatally diagnosed pregnancies VM. VM was classified as mild (Vp = 10–12 mm), moderate 12.1–15 severe > 15 mm). Fetal MRI performed 97 pregnancies. Results The incidences...
Objective: To investigate the association between fetal left ventricular modified myocardial performance index (LMPI) and intrahepatic cholestasis of pregnancy (ICP) to evaluate value LMPI in predicting adverse perinatal outcomes ICP.Study design: In a cross-sectional case–control study, 40 women with ICP were compared gestational age-matched healthy controls. The isovolumetric contraction time (ICT), relaxation (IRT), ejection (ET) measured using Doppler signals opening closing mitral...
To evaluate the value of shear wave elastography (SWE) in prediction morbidly adherent placenta.Forty-three women with normal placental location and 26 anteriorly localized placenta previa were recruited for this case-control study. Placental elasticity values both groups determined by SWE imaging.SWE higher group all regions than placentas (p < .01). However, there was no statistically significant difference between without > .05).Placental stiffness is significantly placentas. we could not...
Aim: The aim of this study was evaluating the effectiveness vitamin D in treatment primary dysmenorrhea.Material and Methods: A total 142 patients between 16 35 years age who were admitted to a university hospital diagnosed with dysmenorrhea included randomized controlled manner. Cases into three groups 667 IU once day, 200 E day 400 mg ibuprofen twice day. given two days before expected date menstruation first menstruation. Treatment continued consecutive cycles. Severity menstrual pain...
Purpose: To investigate the copeptin levels in women with intrahepatic cholestasis of pregnancy (ICP) compared to uncomplicated pregnancies.Materials and methods: This cross-sectional study was conducted 40 pregnant ICP 38 randomly selected healthy women, who formed control group. Serum concentrations were measured using an enzyme-linked immunosorbent assay.Results: Maternal age, body mass index at assessment, gestational age blood sampling similar between two groups. Duration shorter mean...
The aim of the study is to evaluate maternal serum atrial natriuretic peptide (ANP) and brain-type (BNP) levels in patients with getational diabetes mellitus compared a control group.We have measured ANP BNP 35 otherwise healthy 45 gestational diabetic women between week 24 28 referred our unit cross-sectional study. Independent samples t-test or Mann-Whitney U-test was used for comparison two groups where appropriate.Mean homeostasis model assessment insulin resistance (HOMA-IR), HbA1c,...
Aysegul Ozela, Ebru Alici Davutoglua, Sule Yildirimb & Riza Madazlia*a Cerrahpasa Medicine Faculty, Department of Obstetrics and Gynaecology, Istanbul University, Perinatology Unit, Istanbul, Turkey; b Umraniye Training Research Hospital, Turkey
Objective: The present study evaluated the ability of magnetic resonance imaging (MRI) andultrasonography (US) in diagnosing placenta accreta cases anteriorly localized previa with a high risk placental adhesion abnormality. Material and Methods: A total 29 patients having at least one factor for underwent US MRI. Diagnostic both modalities prediction abnormal invasiveness was assessed using various signs described existing literature. Results: Of pregnancies previa, 13 (44.8%) had that...
The aim of the study was to investigate whether plasma irisin concentrations differ between uncomplicated, early-onset and late-onset pre-eclamptic pregnancies. This cross-sectional conducted on 27 women with early-onset, pre-eclampsia (PE) 26 healthy pregnant women. Maternal levels serum were measured use an enzyme-linked immunosorbent assay kit. mean maternal level PE significantly lower than (1.14 ± 0.56 vs. 1.46 0.59, p < .05) control subjects 3.14 0.81, 0.001). group (1.46 0.59 are...
The aim of the study was to investigate whether serum hypoxia-inducible factor-1alpha (HIF-1α), hepcidin and interleukin-6 (IL-6) concentrations differed between threatened preterm labour (TPL) uncomplicated pregnancies. This conducted on 54 women with TDL pregnancies 26 healthy pregnant women. TPL group further divided into two subgroups according gestational age at delivery. Patients who gave birth within 48–72 h after hospitalisation were referred as delivery (PD) ≥37 weeks term (TD)....
The aim of this study was to assess the obstetrical and neonatal outcomes pregnancies in cancer patients survivors. A retrospective analysis 68 with a history 31 newly diagnosed pregnant were included study. mean birth weight gestational age at delivery significantly lower (p < .001). incidences less than 34 weeks 8.8% 29.1% survivors during pregnancy groups respectively .01). In 23 (76.4%) patients, single or combination treatment modalities initiated. There four (12.9%) maternal deaths...
To develop a nomogram for fetal left brachiocephalic vein (LBCV) diameters during healthy pregnancy and to assess LBCV values in fetuses with growth restriction (FGR).This prospective observational study included 31 FGR pregnancies 438 low-risk pregnancies. The group was used determine the 5th, mean, 95th percentiles between 12 39 weeks of gestation based on gestational age. On charts, measurements were displayed, those above age percentile considered wide vein. Cerebroplacental ratio (CPR)...
One hundred and seventy-two twin-pregnant patients were enrolled. The estimated foetal weight was calculated using 19 different formulas. Ong's formula (0.954 (95%CI = 0.938/0.966)), which designed specifically for twins, produced the highest Cronbach's alpha value followed by Hadlock II (0.952 0.935/0.965)), I 0.935/0.964)), III IV 0.935/0.964)) our same values twin A. For B, (0.961 0.948/0.972) (0.960 0.946/0.971)), 0.946/0.970)), 0.946/0.970)) 0.946/0.970)). In conclusion, (AC, FL)...
"An unusual case of Meckel–Gruber syndrome (MKS) associated with visceroatrial heterotaxy and facial anomalies." Journal Obstetrics Gynaecology, 36(4), pp. 524–525
Objective: To evaluate the clinical features and perinatal outcomes of antenatally diagnosed fetuses with omphalocele gastroschisis. Material Methods:This was a retrospective, single-center, cohort study prenatally gastroschisis followed-up delivered at university hospital.Demographic, pregnancy, birth were compared between omphalocele.Results: A total 75 21 cases evaluated.The mean maternal age women carrying fetus significantly higher than (p=0.001).Associated structural anomalies found in...
Background: Toxoplasma Gondii, Rubella, and Cytomegalovirus (CMV) are the most common causes of congenital infections worldwide. There is not a consensus on these infectious agents should be screened during pregnancy. The aim this study to determine prevalence toxoplasma, rubella, CMV in order know need for antenatal screening.Methods: This retrospective cross-sectional was performed 1309 ambulatory pregnant patients who applied obstetric clinic university hospital between October 2016 April...