A5073712001- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Family and Disability Support Research
- Attention Deficit Hyperactivity Disorder
- Child Development and Digital Technology
- Child Nutrition and Feeding Issues
- Hormonal Regulation and Hypertension
- Renal and Vascular Pathologies
- Blood Pressure and Hypertension Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Renin-Angiotensin System Studies
- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Electrolyte and hormonal disorders
- Early Childhood Education and Development
- Mental Health and Psychiatry
- Eicosanoids and Hypertension Pharmacology
- Renal function and acid-base balance
- Health, Environment, Cognitive Aging
- Language Development and Disorders
- Behavioral and Psychological Studies
- Metabolism and Genetic Disorders
- Virology and Viral Diseases
- Vaccine Coverage and Hesitancy
- Genetics and Neurodevelopmental Disorders
University of Exeter
2015-2024
Cambridgeshire and Peterborough NHS Foundation Trust
2021
Genomics (United Kingdom)
2009-2015
King's College London
2015
Peninsula College of Medicine and Dentistry
2012
Royal Stoke University Hospital
1998
Keele University
1995
University of Leicester
1979-1990
University of Naples Federico II
1990
Leicester General Hospital
1979-1989
'Stereotyped or repetitive motor movements' are characterised as core features in the diagnosis of autism, yet many autistic adults (and neurodiversity movement) have reclaimed them 'stimming'. Supported by a growing body scientific research, argue that these behaviours may serve useful coping mechanisms, little research has examined stimming from perspective adults. Through interviews and focus groups, we asked 32 to share their perceptions experiences stimming, including reasons they stim,...
Background Autism spectrum disorder is a diagnosis that increasingly applied; however, previous studies have conflicting findings whether rates of continue to grow in the UK. This study tested proportion people receiving new autism has been increasing over twenty‐year period, both overall and by subgroups. Method Population‐based utilizing Clinical Practice Research Datalink (CPRD) primary care database, which contains patients registered with practices contributing data CPRD between 1998...
BACKGROUND: Loss of residual renal function has a profound effect on the survival peritoneal dialysis patients. Less is known impact function. The purpose this study was to investigate influence solute transport clinical outcome in CAPD METHODS: Two hundred and ten consecutive patients commencing since 1990 were enrolled into single centre prospective longitudinal observational urea, protein, kinetics. On entry, at 6-monthly intervals, estimations made weight, body mass index (BMI), plasma...
Background Studies throughout Northern Europe, the United States and Australia have found an association between childhood attention deficit hyperactivity disorder ( ADHD ) family socioeconomic disadvantage. We report further evidence for review potential causal pathways that might explain link. Method Secondary analysis of a UK birth cohort (the Millennium Cohort Study, N = 19,519) was used to model with disadvantage assess several explanatory pathways. The case definition parent‐report...
Background: Autism has been associated with specific cognitive strengths. Strengths and weaknesses have traditionally conceptualized as dichotomous. Methods: We conducted 28 semi-structured interviews autistic adults. Maximum variation sampling was used to ensure diversity in relation support needs. asked which personal traits adults attributed their autism, how these helped the workplace, relationships, beyond. Data were collected two stages. Responses analyzed using content thematic...
Children from disadvantaged socioeconomic backgrounds are at greater risk of a range negative outcomes throughout their life course than peers; however the specific mechanisms by which status relates to different health in childhood as yet unclear.The current study investigates relationship between disadvantage and attention deficit/hyperactivity disorder (ADHD), putative mediators this association longitudinal population-based birth cohort UK.Data Avon Longitudinal Study Parents was used (n...
Many children who display autistic behaviours at clinical levels do not receive a formal diagnosis. This study used qualitative methods to examine parental influence in pursuing or avoiding diagnosis of autism spectrum disorder (ASD). The aim was explore the function ASD for parents, and whether affected how parents perceived ASD. Seventeen participated in-depth semi-structured interviews, which were analyzed using thematic grounded theory approaches. Data analysis revealed dilemmas faced by...
Thirteen non-diabetic renal transplant recipients had various aspects of carbohydrate and lipid metabolism studied before after conversion from cyclosporin A to azathioprine. No patient a glucose tolerance test result diagnostic diabetes mellitus conversion, there was no change in fasting or immunoreactive insulin values conversion. There was, however, fall the area under curve Furthermore, serum cholesterol triglyceride concentrations fell significantly concentration high density...
The Strengths and Difficulties Questionnaire (SDQ) is widely used as an international standardised instrument measuring child behaviour. primary aim of our study was to examine whether behavioral symptoms measured by SDQ were elevated among children with autism spectrum disorder (ASD) attention deficit hyperactivity (ADHD) relative the rest population, predictive value for outcome parent-reported clinical diagnosis ASD/ADHD. A secondary extent overlap in between diagnosed these two...
Increasing evidence suggests that postnatal paternal depression is associated with adverse emotional, behavioural and cognitive outcomes in children. Despite this, few studies have determined the prevalence of fathers' depressive symptoms during first years their children's lives explored what factors are related to these symptoms. We estimated examined risk a nationally representative sample fathers children aged between 9 months 7 old from Millennium cohort study. The were maternal...
A total of 143 Peritoneal Equilibration Tests (PETs) were performed in 104 CAPD patients over a period 18 months. normal range (95% confidence limits) was constructed from 100 tests (68 consecutive new patients, 32 routine on problem-free patients) using 2-dimensional plot solute transfer (D/Pcreat) and ultrafiltration volume. These two parameters correlated inversely (r = -0.59, P < 0.0001) allowing calculation regression line. In the short term (< 3 months) D/Pcreat stable across wide...
The increased proportion of UK children diagnosed with autism spectrum disorder (ASD) has been attributed to improved identification, rather than true increase in incidence.To explore whether the diagnosis ASD and/or associated behavioural traits had over a 10-year period.A cross-cohort comparison using regression compare prevalence and time. Participants were aged 7 years assessed 1998/1999 (n=8139) 2007/2008 (n=13 831).During 1998/1999, 1.09% (95% CI 0.86-1.37) reported as having compared...
Six patients with hypothyroidism and hypertension whose blood pressure fell to normal when treated thyroxine (172 +/- 7.2/112 2.1 140 3.2/84+/- 1.6 mmHg, P < 0.001) are described. Plasma renin activity (1.76 0.63 ng angiotensin I.ml-1.h-1) was low before treatment. Hypertension plasma is consistent sodium retention. in the hypothyroid patient only requires further evaluation if it persists after adequate treatment thyroxine.
Objective: To compare social and behavioural outcomes between children formally diagnosed with autism spectrum disorders (ASD) those of who displayed autistic traits at preschool age, but remained undiagnosed as teenagers. Method: A secondary analysis data from a birth cohort study, the Avon Longitudinal Study Parents Children ( N = 13,944), in SW England. clinically ASD were identified their medical records n 71). comparison group, age 3–4, without diagnosis also 142). Social adolescence...