Nan Zhang

ORCID: 0000-0002-6441-8022
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Magnesium Alloys: Properties and Applications
  • Calcium Carbonate Crystallization and Inhibition
  • Aluminum Alloys Composites Properties
  • Corrosion Behavior and Inhibition
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Hydrogen Storage and Materials
  • Orthopaedic implants and arthroplasty
  • Additive Manufacturing and 3D Printing Technologies
  • Spine and Intervertebral Disc Pathology
  • Minerals Flotation and Separation Techniques
  • Graphene and Nanomaterials Applications
  • Chemical and Physical Properties in Aqueous Solutions
  • MXene and MAX Phase Materials
  • Connective tissue disorders research
  • Musculoskeletal pain and rehabilitation
  • Nanoparticle-Based Drug Delivery
  • Bone fractures and treatments
  • Metal and Thin Film Mechanics
  • Crystallization and Solubility Studies
  • Advanced Sensor and Energy Harvesting Materials
  • Cervical and Thoracic Myelopathy
  • Phytochemistry and Bioactive Compounds
  • Advanced Welding Techniques Analysis

Dalian University
2021-2025

Harbin Medical University
2018-2024

Second Affiliated Hospital of Harbin Medical University
2018-2024

Affiliated Zhongshan Hospital of Dalian University
2024

Southwest Jiaotong University
2012-2023

Qiqihar Medical University
2017-2023

Tsinghua University
2023

Xi'an University of Technology
2019-2023

Xi’an University
2019-2023

Chinese Academy of Sciences
2021-2023

In this work, a certain amount of dopamine was firstly dissolved into the solution poly(vinylidene fluoride) (PVDF) and then fibrillar membranes were prepared through an electrospinning technology.

10.1039/c7ta02845h article EN Journal of Materials Chemistry A 2017-01-01

The rapid growth of industrialization has resulted in the release large quantities pollutants into environment, especially dyes and heavy metals, which are environmentally hazardous for humans animals. It is considered as most promising friendly route to develop green materials by using modification method, no negative impact on environment. In this work, material polylactic acid (PLA) was used substrate material, a novel method polydopamine (PDA)-assisted polyethyleneimine (PEI) grafting...

10.1021/acs.langmuir.2c03508 article EN Langmuir 2023-03-01

Surgical repair of bone defects remains challenging, and the search for alternative procedures is ongoing. Devices made Mg have received much attention owing to their good biocompatibility mechanical properties. We developed a new type scaffold Mg-Zn-Ca alloy with shape that mimics cortical can be filled morselized bone. evaluated its durability efficacy in rabbit ulna-defect model. Three types scaffold-surface coating were evaluated: group A, no coating; B, 10-μm microarc oxidation C,...

10.1007/s10856-018-6145-2 article EN cc-by Journal of Materials Science Materials in Medicine 2018-08-17

Abstract Clear cell renal carcinoma (ccRCC) presents a unique profile characterized by high levels of angiogenesis and robust vascularization. Understanding the underlying mechanisms driving this heterogeneity is essential for developing effective therapeutic strategies. This study revealed that ubiquitin B (UBB) downregulated in ccRCC, which adversely affects survival ccRCC patients. UBB exerts regulatory control over vascular endothelial growth factor A (VEGFA) directly interacting with...

10.1038/s41388-024-03003-6 article EN cc-by Oncogene 2024-03-11

Regeneration of long-bone segmental defects remains a challenge for orthopedic surgery. Current treatment options often require several revision procedures to maintain acceptable alignment and achieve osseous healing. A novel hollow tubular system utilizing magnesium-strontium (Mg-Sr) alloy with autogenous morselized bone filled inside repair was developed. To improve the corrosion biocompatible properties, two coatings, Ca-P Sr-P were prepared on surface implants. Feasibility applying these...

10.1016/j.bioactmat.2020.11.026 article EN cc-by-nc-nd Bioactive Materials 2020-12-02

Aim: We synthesized MgO NPs via sol-gel reaction and investigated them as carriers to deliver Mg2+ the affected joint for osteoarthritis (OA). Materials & methods: The physicochemical properties of samples were characterized by transmission electron microscope (TEM), dynamic light scattering (DLS) x-ray diffraction (XRD). release was monitored ICP-MS. potential cytotoxicity evaluated using MTT assay. efficacy biosafety in a rabbit OA model. Results: can prolong time from 0.5 h 12 h. No...

10.1080/17435889.2024.2382421 article EN Nanomedicine 2024-08-07

MgO@SiO 2 nanocapsules were synthesized, and the silica coating prevents rapid degradation of nanocrystal controlled magnesium release, which helps to alleviate cartilage damage inflammation caused by OA.

10.1039/d4na00900b article EN cc-by-nc Nanoscale Advances 2025-01-01

A hydrothermal (HT) coating was applied to the biomedical Mg-Zn-Ca alloy surface by microarc oxidation (MAO) and heat treatment. Then, corrosion resistance biocompatibility of coated evaluated in vitro vivo. The rate (CR) HT-coated implants significantly lower experiment. In addition, this CR increased over time vivo but stable, albeit higher, vitro. proliferation, adhesion, live activity bone marrow stem cells (BMSCs) were greater on Mg Serum Mg2+ always within normal range rabbits with...

10.1021/acsomega.9b03889 article EN publisher-specific-oa ACS Omega 2020-02-25

Protein is one of the most abundant natural polymeric materials, but only a few studies on nanoproteins have been conducted. In this paper, novel approach based ultrasound-assisted enzymatic hydrolysis was employed for preparation microkeratin and nanokeratin from wool. The system included solution containing enzyme (esperase) reductant (L-cysteine) treated ultrasonically to remove scales amorphous regions within Results showed that reaction effective at 50 °C pH 7, when incubated 3 h,...

10.1016/j.ultsonch.2020.105201 article EN cc-by-nc-nd Ultrasonics Sonochemistry 2020-05-31

In this work, a novel nucleating agent (NA) based on substituted‐aryl phosphate salts was introduced into poly(L‐Lactide) (PLLA). The nonisothermal and isothermal crystallization behaviors of nucleated PLLA samples were investigated through differential scanning calorimetry (DSC), wide angle X‐ray diffraction, polarized optical microscope (POM). Furthermore, the effect annealing treatment cold also investigated. results show that PLLA, whether for melt (including process) or occurring during...

10.1002/pat.3047 article EN Polymers for Advanced Technologies 2012-05-03

The oil and gas production from deepwater has been challenged due to limited knowledge of mineral solubility inhibitor efficiency at the extreme conditions ultrahigh temperature, pressure, TDS (total dissolved solids) contributed by mixed salts. calcite (CaCO3) was measured for temperatures up 250 °C pressures 1450 bar (21 000 psi) in presence electrolytes. A set stability constants selected based upon experimental measurements, which, together with current Pitzer coefficients activity...

10.1021/ie302190e article EN Industrial & Engineering Chemistry Research 2013-01-08

An ideal behavior of a tissue engineering scaffold is that it degrades and reshapes at rate matches the formation new tissues. However, this situation may not occur as often undergoes too slow or fast degradation. To test promise active control degradation, in work, photo/water dual-degradable porous was designed fabricated using 3D fiber deposition (3DF) system from linear biopolymer (named PLANB) combined o-nitrobenzyl linkages hydrolysable ester bone polymer chains. The chemical...

10.1039/c6tb02884e article EN Journal of Materials Chemistry B 2016-11-25
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