A5066258774- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Microbial Metabolism and Applications
- COVID-19 Clinical Research Studies
- Helicobacter pylori-related gastroenterology studies
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Identification and Susceptibility Testing
- melanin and skin pigmentation
- Vibrio bacteria research studies
- Antibiotic Use and Resistance
- S100 Proteins and Annexins
- Phagocytosis and Immune Regulation
- RNA modifications and cancer
- Circular RNAs in diseases
- Biochemical and Structural Characterization
- Antifungal resistance and susceptibility
- Urinary Tract Infections Management
- Antimicrobial agents and applications
- Essential Oils and Antimicrobial Activity
- Medical and Biological Ozone Research
- Immunotherapy and Immune Responses
- Food Industry and Aquatic Biology
- Herbal Medicine Research Studies
- Cancer-related molecular mechanisms research
Menoufia University
2015-2024
Objectives The aims of the study were to determine bacterial pathogens frequently causing burn infections and their antimicrobial susceptibility patterns, estimate prevalence multidrug resistance (MDR) among isolated pathogens, evaluate different risk factors for development wound infection. Background Infection in patients remains significant source morbidity mortality. aggressive use antimicrobials has improved survival but led an increased colonization infection that resist current...
Background: Nosocomial infection with multidrug resistant biofilm formingAcinetobacter baumanii is a serious problem in healthcare settings worldwide concern.Objectives: To study the prevalence and antimicrobial resistance profiles of Acinetobacter isolates detect formation correlate FimH bap genes drug resistance.Methodology: This was retrospective performed medical microbiology immunology department, faculty medicine, Menoufia university hospitals.Acinetobacter baumannii were isolated from...
Despite significant advancements in the molecular characterization of hepatocellular carcinoma (HCC), no oncogene addiction has been discovered. Long noncoding RNAs (lncRNAs) have a lot promise as cancer biomarkers. LINC00152 and UCA1 shown potential diagnostic, prognostic, therapeutic targets for human cancers.To investigate diagnostic prognostic serum (HCC).The expression levels blood samples from 120 patients (60 with HCC, 60 liver cirrhosis) 40 healthy subjects were assessed using...
Vitiligo is an acquired depigmented skin disorder. It has a genetic and autoimmune background. Human beta defensin-1(HBD-1) plus its gene polymorphism were linked to some disorders.To elucidate the possible role of HBD-1 in pathogenesis non-segmental vitiligo (NSV) through evaluation serum levels single nucleotide (SNP) patients having NSV, addition, correlating results with extent those patients.A current case-control study included 50 NSV controls. The authors used Area Scoring Index...
Reports examine quinolone resistance mechanisms among
Background: Colistin is the last treatment option for infections caused by carbapenem resistant Gram-negative bacilli (CRGNB).The increasing spread of chromosomally encoded and plasmid-mediated colistin resistance made susceptibility assessment a necessity.Objectives: Assessment in CRGNB broth micro dilution method (BMD), as standard disk elution (CBDE), substitute procedure with genotypic determination plasmid mediated (mcr) genes.Methodology: were collected identified conventional...
Background: Staphylococcus aureus (S. aureus) is a world-wide nosocomial and community-acquired infectious agent.This study aimed to determine the prevalence rate of S. infections with assessment their antibiotic susceptibility patterns virulence profiles using available phenotypic genotypic methods.Methodology: isolates were collected identified by conventional methods.Antimicrobial testing was done interpreted according Clinical Laboratory Standards Institute guidelines (2022) followed...
Background: P. aeruginosa is a worrisome multidrug (MDR) or even extensively drug-resistant (XDR) nosocomial pathogen. Ceftolozane/tazobactam(C/T) and ceftazidime/avibactam (CAZ/AVI), novel combinations, were recently approved for the treatment of MDR Gram-negative pathogens. Objective: To assess in vitro activity C/T & CAZ/AVI against MDR/XDR isolates , detect synergistic plus aztreonam (ATM) metallo-β- lactamase )MβL( producers to determine virulence profile studied isolates. Methods:...
The emergence of methicillin-resistant
Background: Neonatal bloodstream infections caused by multidrug-resistant Klebsiella pneumoniae present a major public health challenge in developing countries, with efflux pumps being key resistance mechanism Gram-negative pathogens. This study aimed to detect NICUs, analyze antimicrobial susceptibility patterns, and assess the role of resistance. Methods: A total 44 isolates were collected from blood 205 clinically suspected neonates out 405 admitted cases NICU at Menoufia University...
S100A8 single nucleotide polymorphism (SNP) and blood level are related to many inflammatory disorders with no available conclusion in psoriasis.The aim of this study was evaluate the possible role psoriasis pathogenesis through analyzing its (rs3806232) gene serum vulgaris patients, addition correlate detected results severity those patients.This case-control conducted on 50 patients having vulgaris, 26 controls. Severity evaluated using area index (PASI) score. SNP were by ELISA polymerase...
Background: Vulvovaginal candidiasis (VVC) is one of the most common forms superficial fungal infections.Azoles are first line antifungals used in treatment and prevention VVC.Objectives: This study aimed to determine prevalence rate VVC with evaluation potential risk factors.Also, assess azoles susceptibility patterns association biofilm formation detect candidal virulence genes (HWP1, ALS1 INT1) ERG11 gene expression.Methodology: Evaluation vaginal infection factors was achieved by a...
Objectives: To assess glycerol antibacterial activity against both Gram positive and negative microorganisms, detect impact of increasing concentration in bacterial cultures on extra/ intracellular Glycerol-3-phosphate (G3P) concentration, evaluate antiseptic efficacy different glycerol/alcohol formulations monitor HCWs tolerability to these recommend the best preparation vitro. Background: The progressively rising nosocomial infections have enforced need for novel infection prevention...
Introduction. The host genetic background is a crucial factor that underlies the interindividual variability of COVID-19 fatality and outcomes. Angiotensin-converting enzyme-2 (ACE-2) interferon-induced transmembrane protein-3 (IFITM-3) have key role in viral cell entrance priming. evoked immune response will also provide predictive prognosis for infection. This study aimed to explore association between ACE-2 IFITM-3 genotypes their corresponding allele frequencies with disease severity...
Background:The global allocation and high level of frequency with the consequence related pathologies make eradication Helicobacter pylori is a very useful advance to test treat.In addition, determination genotype H. isolates helps us comprehend correlation between assumed virulence genes clinical disease out come.Objectives: To determine prevalence infections in patients complaining gastric disorders, best phenotypic method for detection antimicrobial susceptibility patterns among isolated...
Background and Aim: Coronaviruses are dangerous human animal pathogens.It is characterized by fast spread, starting as an epidemic through China, followed a worldwide pandemic.This study aimed to determine the prevalence of laboratory proven blood stream bacterial co-infection in hospitalized adult COVID-19 Egyptian patients recognize antibiotic susceptibilities identified pathogens together with evaluation predictors for case severity.Methods:The involved 142 patients.The diagnosis was...