Lan Liu

ORCID: 0000-0002-6489-212X
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About
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Research Areas
  • Nasolacrimal Duct Obstruction Treatments
  • Maternal Mental Health During Pregnancy and Postpartum
  • Gynecological conditions and treatments
  • Neurological Disease Mechanisms and Treatments
  • Acupuncture Treatment Research Studies
  • Child and Adolescent Health
  • Angiogenesis and VEGF in Cancer
  • Nerve injury and regeneration
  • Gestational Diabetes Research and Management
  • Sinusitis and nasal conditions
  • Ocular Diseases and Behçet’s Syndrome
  • Ovarian function and disorders
  • Gestational Trophoblastic Disease Studies
  • Neurogenetic and Muscular Disorders Research
  • Ocular Surface and Contact Lens
  • Diabetic Foot Ulcer Assessment and Management
  • Toxoplasma gondii Research Studies
  • Maternal and Perinatal Health Interventions
  • Ectopic Pregnancy Diagnosis and Management
  • Assisted Reproductive Technology and Twin Pregnancy
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Wound Healing and Treatments
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Evolution and Genetic Dynamics
  • COVID-19 epidemiological studies

Scholar Rock (United States)
2024

National Institutes for Food and Drug Control
2022

Putian University
2004-2020

XinHua Hospital
2018-2020

Shanghai Jiao Tong University
2018-2020

Songjiang District Central Hospital
2020

Shanghai First People's Hospital
2020

Hunan University
2018

Nanjing Maternity and Child Health Care Hospital
2016

Nanjing Medical University
2016

In 2010, Nicaragua became the first developing nation to add 13-valent pneumococcal conjugate vaccine (PCV-13) its national immunization schedule, using a "3+0" dosing schedule. We assessed changes in incidence rates of health facility visits for childhood pneumonia and infant mortality after PCV-13 introduction Department León, Nicaragua.We collected visit diagnoses from all 107 public facilities León between 2008 2012. compared hospitalizations, ambulatory during prevaccine (2008-2010)...

10.1097/inf.0000000000000269 article EN The Pediatric Infectious Disease Journal 2014-01-20

Background and purpose At 12 months in the phase 2 TOPAZ study, treatment with apitegromab was associated both an improved motor function patients Type or 3 spinal muscular atrophy (SMA) a favorable safety profile. This manuscript reports extended efficacy nonambulatory group of study at 36 months. Methods Patients who completed primary (NCT03921528) could enroll open-label extension, during which received 20 mg/kg by intravenous infusion every 4 weeks. were assessed periodically via...

10.3389/fneur.2024.1419791 article EN cc-by Frontiers in Neurology 2024-07-22

Owing to the outbreak of novel coronavirus (SARS-CoV-2) worldwide at end 2019, development a SARS-CoV-2 vaccine became an urgent need. In this study, we developed type 9 adeno-associated virus vectored candidate expressing dimeric receptor binding domain (RBD) spike protein (S protein) and evaluated its immunogenicity in murine model. The candidate, named AAV9-RBD virus, was constructed by inserting signal peptide N-terminus two copies RBD, spaced linker, into genome virus. vitro assays...

10.3389/fcimb.2022.802147 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-03-03

Offspring obesity is one of long-term complications gestational diabetes mellitus (GDM). The aim this study to identify proteins differentially expressed in the umbilical vein blood plasma, which could become markers for early diagnosis childhood obesity.Umbilical plasma samples were collected from 30 control and GDM patients 2007-2008 whose offspring suffering at 6-7 years old. Multiplexed isobaric tandem mass tag labeling combined with LC-MS/MS was used proteins. Ingenuity pathway analysis...

10.1002/prca.201600046 article EN PROTEOMICS - CLINICAL APPLICATIONS 2016-07-06

In this paper, a delayed viral infection model with nonlinear immune responseand general incidence rate is discussed. We prove the existence and uniqueness of equilibria. study effect three kinds time delays on dynamics model. By using Lyapunov functional LaSalle invariance principle, we obtain conditions global stabilities infection-free equilibrium, immune-exhausted equilibrium endemic equilibrium. It shown that an increase viral-infection delay virus-production may stabilize but response...

10.3934/dcdsb.2016.21.133 article EN Discrete and Continuous Dynamical Systems - B 2015-11-01

Objective To investigate ultrasonographic characteristics and diagnostic approaches of unruptured tubal pregnancy (UTP). Methods One hundred forty-six cases early pregnancy, which were confirmed surgically, analyzed. Results Among 146 UTP, 130 diagnosed by ultrasonography. Furthermore, 16 UTP missed A total patients had a mass detected ultrasonography, among whom the ipsilateral ovary distinguishable in 102. The embryo sac type was found 40.00% (52/130), while heterogeneous 60.00% (78/130)...

10.1177/0300060519894436 article EN cc-by-nc Journal of International Medical Research 2020-05-01

Artificial insemination with the husband's semen (AIH) is an economical and noninvasive method of infertility treatment. However, AIH's pregnancy rate much lower than in vitro fertilization (IVF) as its multiple complex uncertainty factors. Semen quality has been one main factors which affect outcome AIH.The relevant parameters 1,142 AIH cycles were retrospectively studied, including general among clinical pregnancy, biochemical non-pregnancy group, age, duration, type, body mass index...

10.21037/tau-20-1385 article EN Translational Andrology and Urology 2020-12-01

Objective: To manifested the clinic features in two cases of cytomegalovirus(CMV) retinitis Chinese patients non-Hodgkin lymphoma with normal CD4 counts. Methods: Two presented floaters and vision reduction affected eyes. The patient underwent eye examination blood investigation, vitreous was extracted for CMV-DNA polymerase chain reaction (PCR). treated intravenous intravitreal ganciclovir. Results: Funduscopy showed typical yellow white lesions retina Blood investigation HIV(-), CMV-...

10.5455/ijmr.20140301065114 article EN International Journal of Medical Research 2013-01-01

Diabetic foot is a common complication in diabetic patients.Infections and poor prognosisof wounds are plaguing the majority of world's clinicians patients.Vacuum sealing drainage(VSD) could drain wound,prevent bacterial invasion which contribute to clean wound as quickly possible.Furthermore,continuous negative pressure can significantly improve state local microcirculation.Therefore,VSD with particular mechanisms processes plays multiple roles on treatment foot. Key words: Vacuum...

10.3760/cma.j.issn.1673-4157.2012.05.008 article EN Intern J Endocrinol Metab 2012-09-20

Objective To evaluate the clinical effect of dacryocystorhinostomy under nasal endoscope combined with lacrimal duct catheterization. Methods The retrospective comparative study was used to analyze 120 patients chronic dacryocystitis in our hospital from June, 2012 May, 2016, whom 60 were treated traditional dacryocystorhinostomy, and catheterization. Half year after operation re-examined for patency their passages postoperative complication. The disappearance tearing unobstructed set...

10.3760/cma.j.issn.1008-1372.2018.01.025 article EN 2018-01-20
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