Henrik Janning

ORCID: 0000-0002-6497-6972
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Macrophage Migration Inhibitory Factor
  • Aortic Disease and Treatment Approaches

University of Tübingen
2024

BACKGROUND: Aortic stenosis (AS) is driven by progressive inflammatory and fibrocalcific processes regulated circulating valve resident endothelial interstitial cells. The impact of platelets, platelet-derived mediators, platelet-monocyte interactions on the acceleration local valvular inflammation mineralization presently unknown. METHODS: We prospectively enrolled 475 consecutive patients with severe symptomatic AS undergoing aortic replacement. Clinical workup included repetitive...

10.1161/atvbaha.124.321000 article EN Arteriosclerosis Thrombosis and Vascular Biology 2024-09-01
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