A5041283743- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Insects and Parasite Interactions
- Galectins and Cancer Biology
- Dermatology and Skin Diseases
- Helicobacter pylori-related gastroenterology studies
- Herbal Medicine Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Transgenic Plants and Applications
- Asthma and respiratory diseases
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
National Taiwan University
2008-2013
Abstract Although cockroaches are known to produce allergens that can cause IgE‐mediated hypersensitivity reactions, including perennial rhinitis and asthma, the various cockroach have not yet been fully studied. Many proteins from German show high IgE reactivity, but never comprehensively characterized. To identify these potential allergens, were separated by 2‐DE IgE‐binding analyzed nanoLC‐MS/MS or N ‐terminal sequencing analysis. Using a combination of proteomic techniques bioinformatic...
Previous studies have demonstrated that valosin-containing protein (VCP) is associated with H. pylori-induced gastric carcinogenesis. By identifying the interactome of VCP overexpressed in AGS cells using a subtractive proteomics approach, we aimed to characterize cellular responses mediated by and its functional roles pylori-associated cancer. immunoprecipitations followed proteomic analysis identified 288 putative interacting proteins, 18 VCP-binding proteins belonged PI3K/Akt signaling...
Background Pen c 13, identified as a 33-kDa alkaline serine protease, is major allergen secreted by Penicillium citrinum. Detailed knowledge about the epitopes responsible for IgE binding would help inform diagnosis/prognosis of fungal allergy and facilitate rational design hypoallergenic candidate vaccines. The goal present study was to characterize 13. Methodology/Principal Findings Serum samples were collected from 10 patients with mold positive 13 skin test results. IgE-binding on rPen...
This article was originally published in Proteomics 2010, 10 , 3854–3867, DOI 10.1002/pmic.201000348
MEETING ABSTRACTS: Abstracts from the Fifth Georg Rajka International Symposium of Atopic Dermatitis, Kyoto, Japan, May 11-13, 2008: Part 1: 6. Role Allergens and Food Allergy in Dermatitis