A5076434048- Spaceflight effects on biology
- Advanced Glycation End Products research
- Lipoproteins and Cardiovascular Health
- Cardiac electrophysiology and arrhythmias
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammatory mediators and NSAID effects
- Autophagy in Disease and Therapy
- Skin Protection and Aging
- Tryptophan and brain disorders
- Cancer, Lipids, and Metabolism
- Hair Growth and Disorders
- Exercise and Physiological Responses
- Dermatologic Treatments and Research
- Probiotics and Fermented Foods
- Occupational Health and Performance
- Atherosclerosis and Cardiovascular Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Clostridium difficile and Clostridium perfringens research
- melanin and skin pigmentation
- Personality Traits and Psychology
- Facial Rejuvenation and Surgery Techniques
- Gut microbiota and health
- Allergic Rhinitis and Sensitization
- Neuroendocrine regulation and behavior
- Immune Response and Inflammation
Surgical Specialties (Canada)
2024
University of Brescia
2024
Fondazione G.B. Bietti
2024
Universidad Complutense de Madrid
2023-2024
Hospital Clínico San Carlos
2023-2024
Ministry of Law and Justice
2023-2024
Italian Society of Physiotherapy
2024
Institute of Aviation Medicine
2023
University of Pavia
2003-2014
Alessandro Manzoni Hospital
2006-2010
In this narrative review, we sought to provide a comprehensive overview of the mechanisms underlying cutaneous senescence, framed by twelve traditional hallmarks aging. These include genomic instability, telomere attrition, epigenetic alterations, loss proteostasis, impaired macroautophagy, deregulated nutrient sensing, mitochondrial dysfunction, cellular stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. We also examined how topical interventions...
Aims Levels of the secreted glycophosphoprotein osteopontin (OPN) have been associated with presence and extent coronary artery disease (CAD). The present study assessed relationship between plasma OPN concentrations prognosis in patients chronic stable angina (CSA).
Aviophobia (AP), or fear of flying, is a common situational phobia that can profoundly impact an individual's personal, social, and professional life. Investigating personality traits through the framework five-factor model (FFM) their relationship to AP may offer valuable insights with potential applications in preventive therapeutic interventions. Here, we conducted case-control analysis comparing "big five" dimensions between individuals frequent fliers (FFs). We specifically selected FFs...
Background: Melasma is a chronic hyperpigmentary disorder exacerbated by sun exposure, characterized asymptomatic hyperpigmented macules and patches. Its pathogenesis involves ultraviolet B (UVB)-induced activation of melanogenesis pathways, including arachidonic acid (AA) metabolism, alpha-melanocyte-stimulating hormone (α-MSH) secretion, melanin synthesis. This study aimed to evaluate the efficacy multi-ingredient skin-lightening formulation (3% tranexamic acid, 2% ascorbyl glucoside, 2.5%...
Autophagy is a major clearance mechanism that degrades organelles and large protein aggregates to maintain cell survival homeostasis. Although induction of autophagy can promote longevity in experimental models, the question as whether increased basal levels be associated with human remains open. In this pilot study, we investigated association between serum concentrations beclin-1, key regulator autophagy, exceptional (EL). Serum beclin-1 was measured three study groups: 79 healthy...
Background: Hyaluronic acid (HA), glucosamine (Glc), and chondroitin sulfate (CS) are key ingredients commonly incorporated into dietary chondroprotective supplements for the management of osteoarthritis (OA). Despite their widespread use, there is a paucity published data regarding efficacy safety, necessitating rigorous investigation in clinical settings. To address this knowledge gap, we conducted randomized, single-blind pilot study to evaluate effects two commercially available...
Background 1,4-butanediol diglycidyl ether (BDDE) is the most common cross-linker used to produce hyaluronic acid (HA)-based dermal fillers. However, BDDE may have cytotoxic and potentially mutagenic effects, raising safety concerns. Consequently, manufacturers are developing new HA filler formulations with reduced levels mitigate potential biological risks. Here, we sought evaluate clinical outcomes of lip augmentation performed using an HA-based a content (Agex Fill Volume®; Biodue SpA,...
Cellulite, which appears as orange peel-type or cottage cheese-like dimpling of the skin on thighs and buttocks, is a complex, multifactorial, cosmetic disorder subcutaneous fat layer overlying superficial skin. Adiponectin an adipocyte-derived hormone mainly produced by that shows important protective anti-inflammatory vasodilatory effects. We hypothesized adiponectin expressed in adipose tissue (SAT) might play role pathogenesis cellulite. reasoned reduction expression - humoral...
The term "WORKbiota" has been used to describe the impact of occupational exposure and work types on human microbiota composition. Airline pilots, construction workers, fitness instructors encompass three diverse professional groups, each with distinct environments lifestyle factors that may significantly influence their intestinal "WORKbiota."The current preliminary investigation was aimed compare relative abundance specific gut microbes among airline shed light any significant differences....