A5021958966- Antibiotic Use and Resistance
- Pharmaceutical Practices and Patient Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical studies and practices
- Patient Satisfaction in Healthcare
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Drug-Induced Adverse Reactions
- Antibiotic Resistance in Bacteria
- Patient Safety and Medication Errors
- Poisoning and overdose treatments
- COVID-19 Clinical Research Studies
- Intravenous Infusion Technology and Safety
- Complementary and Alternative Medicine Studies
- Health Systems, Economic Evaluations, Quality of Life
- Pneumocystis jirovecii pneumonia detection and treatment
- Healthcare Operations and Scheduling Optimization
- Microscopic Colitis
- Emergency and Acute Care Studies
- Cardiac pacing and defibrillation studies
- Drug-Induced Hepatotoxicity and Protection
- Pneumonia and Respiratory Infections
- COVID-19 and healthcare impacts
- Intramuscular injections and effects
- Urinary Bladder and Prostate Research
Fiona Stanley Hospital
2016-2024
Fremantle Hospital
2024
Fiona Stanley Fremantle Hospitals Group
2024
Emerald Group Publishing (United Kingdom)
2023
Society of Hospital Pharmacists of Australia
2021
The University of Queensland
2020
Royal Perth Hospital
2012-2015
Royal Navy
2014
Derriford Hospital
2014
Virginia Mason Medical Center
2003
The global problem of antibiotic resistance is threatening us.Since 2001, the proportion methicillin-resistant Staphylococcus aureus (MRSA) infections in community has doubled. Antibiotic use and AustraliaAustralia one highest users antibiotics developed world, with around 22 million prescriptions written every year primary care.The defined daily dose Australia nearly 23/1000 population/day compared less than 15 for Denmark, Netherlands Sweden (Fig. 1). [2][4][5] In hospitalsThe...
Acute kidney injury is a common complication present in critically ill patients and often managed by replacement therapy. Prolonged intermittent therapy (PIKRT) modality of utilized intensive care settings, but dosing recommendations pharmacokinetic data for antimicrobial removal during PIKRT are limited. Metronidazole, 5-nitroimidazole agent, commonly prescribed anaerobic protozoal infections. Although generally well tolerated, adverse effects including severe neurotoxicity have been...
Infliximab has been proven effective for treatment of active Crohn's and fistulizing disease. We reviewed our experience with infliximab in patients disease to determine if its combination immunomodulators leads better response longer periods quiescence.We performed a retrospective chart review 122 who received infusions. Data were collected on patient demographics, clinical infliximab, fistula response, prednisone dose, infusion reactions/side effects, concomitant immunomodulator therapy,...
Abstract Penicillin allergy is a significant burden on patient, prescribing and hospital outcomes. There has been increasing interest in the incorporation of penicillin testing (i.e. delabelling) into antimicrobial stewardship (AMS) programmes to reduce labels improve prescribing. In particular, there focus point‐of‐care assessment direct oral challenge for low‐risk phenotypes. The National Antibiotic Allergy Network provided guide assist AMS clinicians with programmes, particular challenge,...
The coronavirus disease 2019 (COVID-19) pandemic has greatly impacted healthcare services around the world. Pharmacists are front-line professionals and integral members of team. deployment a specialized 'COVID pharmacist' within our institution demonstrated that skills pharmacist can be adapted, expanded utilized to alleviate pressure doctor shortages, reduce worker exposure infected patients, contribute therapeutic decisions work collaboratively tackle challenges faced during this...
Western Australia (WA) was in a unique position to experience coronavirus disease 2019 (COVID-19) highly vaccinated and geographically isolated population.To describe the COVID-19 Omicron at only quaternary hospital WA following border opening from 3 March 11 May 2022.A total of 158 adults with microbiologically confirmed were admitted respiratory or intensive care unit (ICU).Admission numbers, severity, prevalence deterioration risk factors, immunisation status, severity infection,...
Little is known about the use of complementary medicines by people living with HIV in Australia since advent more effective combination antiretroviral therapy. We conducted an anonymous survey 1211 adult patients receiving therapy from one eight specialist clinics across Australia, aiming to identify current patterns ingestible medicines. Data collected included reasons for use, information sources and rates disclosure medical practitioners pharmacists. Ingestible medicine was used up 53%...
Prevention of urinary tract infection (UTI) after spinal cord injury is an important goal. Intravesical hyaluronic acid with chondroitin sulphate (HA+CS) has been effective in preventing UTI other settings. We aimed to demonstrate safety and feasibility a standard treatment course 7 intravesical HA+CS instillations over 12 weeks, patients acute (Arm A) chronic B) (SCI).Follow-up adverse events, quality life bladder management difficulty (BMD) complication (BC) T-scores at baseline B only),...
To evaluate the impact of adaptation an existing electronic referral application for use in antimicrobial stewardship prospective audit and feedback rounds (antimicrobial rounds).Retrospective, single-centre observational study between March 2015 February 2016.A new quaternary centre.Adults referred outside intensive care haematology units.Adaptation used by medical allied health staff. A questionnaire-style form was designed to capture patient clinical details using a combination free text...
<b><i>Background:</i></b> Prolonged intermittent renal replacement therapy (PIRRT) eliminates many drugs, and without dosing data, for new antibiotics like ceftolozane/tazobactam, suboptimal concentrations treatment failure are likely. <b><i>Objectives:</i></b> Herein, we describe the effect of PIRRT on plasma pharmacokinetics ceftolozane/tazobactam administered in a critically ill 55-year-old patient with polymicrobial sternal wound...
Prolonged intermittent renal replacement therapy (PIRRT) is an increasingly adopted method of in critically ill patients. Like continuous therapy, PIRRT can alter the pharmacokinetics (PK) many drugs. In this setting, dosing data for antibiotics like benzylpenicillin are lacking. order to enable clinicians prescribe safely and effectively, knowledge effects on plasma PK required. Herein, we describe 2 patients treatment penicillin-susceptible <i>Staphylococcus aureus</i>...
We examined adherence to antimicrobial stewardship prospective audit and feedback rounds in a rehabilitation service compared with the remainder of acute hospital, explored reasons for this. Between October 2014 December 2015, we retrospectively assessed rate non-adherence advice from between along source patient referral. Compared service, hospital medical staff were almost twice as likely not adhere provided on (13.8% vs. 7.6%, p < 0.0001, relative risk 1.8 [95% confidence interval 1.3,...
Although common, antimicrobial allergy labels (AAL) rarely reflect immunologically-mediated hypersensitivity and can lead to poorer outcomes from alternative agents. Antimicrobial stewardship programs are ideally placed assess AAL early as a means of improving use.To quantify the prevalence in patients referred for review their impact on antibiotic prescribing, patient mortality, hospital length stay, readmission rates multidrug-resistant infections.We conducted retrospective analysis adult...