- Inhalation and Respiratory Drug Delivery
- RNA Interference and Gene Delivery
- Lipid Membrane Structure and Behavior
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Biopolymer Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Drug Delivery Systems
- Cancer Treatment and Pharmacology
- Advancements in Transdermal Drug Delivery
- Spacecraft and Cryogenic Technologies
- Neonatal Respiratory Health Research
Alexandria University
2017-2020
Damanhour University
2019-2020
Liquid crystalline assembly for potential combinatorial chemo-herbal drug delivery to lung cancer cells Hadeer M Abdelaziz,1,2 Ahmed O Elzoghby,1,3–5 Maged W Helmy,1,6 Magda Samaha,1,3 Jia-You Fang,7–9 May S Freag1,4,5,10 1Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, 21521, Egypt; 2Department Pharmaceutics, Damanhur Damanhur, 3Department Industrial 4Division Engineering in Medicine, Department Brigham and Women's Hospital, Harvard Medical...
Localized drug delivery to lung cancer can overcome the limitations of systemic nanocarriers including low amounts reaching tissues and severe off-target toxicity. The current work presented novel inhalable nanocomposites as noninvasive platforms for therapy. Nanoparticulate liquid crystals (LCNPs) based on monoolein were developed synergistic co-encapsulation cytotoxic chemotherapeutic drug, pemetrexed, phytoherbal resveratrol (PEM-RES-LCNPs). For active tumor targeting, lactoferrin (LF)...