Abstract Background The stability of Variable Importance Measures (VIMs) based on random forest has recently received increased attention. Despite the extensive attention traditional data perturbations or parameter variations, few studies include influences coming from intrinsic randomness in generating VIMs, i.e. bagging, randomization and permutation. To address these influences, this paper we introduce a new concept which is defined as self-consistence among feature rankings repeated runs...

<title>Abstract</title> Objective: To explore the relationship between preoperative nutritional index (PNI) and systemic immune inflammatory (SII) levels postoperative delirium (POD) in patients undergoing thoracoscopic surgery, risk factorsfor POD during surgery. Methods: This study selected 106 who underwent surgery under general anesthesia at a tertiary hospital. One day before Mini Mental State Evaluation Scale (MMSE) was used to evaluate cognitive function of surgical patients. The...

Most machine-learning classifiers output label predictions for new instances without indicating how reliable the are. The applicability of these is limited in critical domains where incorrect have serious consequences, like medical diagnosis. Further, default assumption equal misclassification costs most likely violated diagnosis.In this paper, we present a modified random forest classifier which incorporated into conformal predictor scheme. A transductive learning scheme, using Kolmogorov...

Objective Chronic Fatigue (CF) still remains unclear about its etiology, pathophysiology, nomenclature and diagnostic criteria in the medical community. Traditional Chinese medicine (TCM) adopts a unique method, namely ‘bian zheng lun zhi’ or syndrome differentiation, to diagnose CF with set of factors, which can be regarded as Multi-Label Learning (MLL) problem machine learning literature. To obtain an effective reliable tool, we use Conformal Predictor (CP), Random Forest (RF) Problem...

Benefiting from big data, powerful computation and new algorithmic techniques, we have been witnessing the renaissance of deep learning, particularly combination natural language processing (NLP) neural networks. The advent electronic medical records (EMRs) has not only changed format but also helped users to obtain information faster. However, there are many challenges regarding researching directly using Chinese EMRs, such as low quality, huge quantity, imbalance, semi-structure...

In the biomineralization of NiCO₃, secondary structure extracellular proteins changed from α-helices to β structures.

Abstract The Drosophila genome encodes three BEN-solo proteins including Insensitive (Insv), Elba1 and Elba2 that possess activities in transcriptional repression chromatin insulation. A fourth protein—Elba3—bridges to form an ELBA complex. Here, we report comprehensive investigation of these embryos. We assess common distinct binding sites for Insv their genetic interdependencies. While generally requires the complex, Elba3 can associate with independently Elba2. further demonstrate...

Intent detection and slot filling are important modules in task-oriented dialog systems. In order to make full use of the relationship between different resource sharing, solving problem a lack semantics, this paper proposes multitasking learning intent-detection system, based on knowledge-base slot-filling joint model. The approach has been used share information rich external utility intent three-part process. First, model obtains shared parameters features two long short-term memory...

Extant research on design thinking is subjective and limited. This manuscript combines protocol analysis electroencephalogram (EEG) to read thoughts in the core activities of concept generation phase. The results suggest that alpha band power had event related synchronization (ERS) scenario task divergent occupies a dominant position. However, it desynchronization (ERD) analogy inference activities, etc., stronger for mental pressure exercised cognitive processing. In addition,...

Atelectasis typically denotes the partial or complete collapse of lung segments, lobes, lobules in individuals, leading to a compromised respiratory function. The prevalence perioperative atelectasis may be significantly underestimated, particularly among patients subjected general anesthesia.

Abstract Background Transfection in mammalian cells based on liposome presents great challenge for biological professionals. To protect themselves from exogenous insults, tend to manifest poor transfection efficiency. In order gain high efficiency, we have optimize several conditions of transfection, such as amount liposome, plasmid, and cell density at transfection. However, this process may be time-consuming energy-consuming. Fortunately, mathematical methods, developed the past decades,...

In modern advanced genetics and breeding programs, the study of genes related to pigmentation in ducks is gaining much attention popularity. Genes DNA mutation cause variations plumage color traits ducks. Therefore, discovering responsible for different pigment patterns on each side single feathers Chinese important genetic studies. this study, we collected feather images from 340 transported them into Image Pro Plus (IPP) 6.0 software quantify melanin content feathers. Thereafter, a...

Most of state-of-the-art machine learning algorithms cannot provide a reliable measure their classifications and predictions. This paper addresses the importance reliability confidence for classification, presents novel method based on combination unexcelled ensemble method, random forest (RF), transductive (TCM) which we call TCM-RF. The new algorithm hedges predictions RF gives well-calibrated region prediction by using proximity matrix generated with as nonconformity examples. takes...

Abstract Epithelial tissue fusion requires coordinated molecular events at the ends of two epithelial structures. Regulatory mechanisms controlling these remain largely elusive. In Drosophila reproductive system (RS), this unites gonad and genital disc-derived tissues, into a continuous tube. This study unveils pivotal role Hamlet (Ham), PR-domain containing transcription factor, in orchestrating RS. Loss ham leads to sterility disconnection between testes (TE) seminal vesicles (SV)....

Anesthesia management of patients with dilated cardiomyopathy (DCM) has always been a challenge for anesthesiologists. Eighty percent DCM have heart failure as the first symptom, which may be accompanied by arrhythmias, thromboembolism, etc. Thrombosis is significant contributing factor to adverse cardiovascular and cerebrovascular events, its risk severely underestimated in anesthetic DCM.

Hybrid breeding has proven to enhance meat quality and is extensively utilized in goose breeding. Nevertheless, there a paucity of research investigating the molecular mechanisms that underlie hybrid geese. In this study, we employed Sichuan White Goose as maternal line for hybridization with Zhedong Tianfu Meat P3 line. We assessed growth slaughter performance 10-wk-old offspring comparison white purebred offspring. The results indicate geese have significantly improved quality....

The primary feathers of ducks have important economic value in the poultry industry. This study quantified feather phenotype Nonghua ducks, including feathers' length, area, distribution black spots, and symmetry. And genome-wide association analysis was used to screen candidate genes that affect traits. (GWAS) results identified genetic region related length (FL) on chromosome 2. Through Linkage disequilibrium (LD) analysis, regions (chr2: 115,246,393-116,501,448 bp) were further annotated...

Epithelial tissue fusion requires coordinated molecular events at the ends of two epithelial structures. Regulatory mechanisms controlling these remain largely elusive. In Drosophila reproductive system (RS), this unites gonad and genital disc-derived tissues, into a continuous tube. This study unveils pivotal role Hamlet (Ham), PR-domain containing transcription factor, in orchestrating RS. Loss ham leads to sterility disconnection between testes (TE) seminal vesicles (SV). Systematic...