A5002725372- biodegradable polymer synthesis and properties
- Phase Equilibria and Thermodynamics
- Nanoparticle-Based Drug Delivery
- Polymer Foaming and Composites
- Carbon dioxide utilization in catalysis
- Electrospun Nanofibers in Biomedical Applications
- Chemical Thermodynamics and Molecular Structure
- Polysaccharides Composition and Applications
- Supramolecular Self-Assembly in Materials
- Phytochemicals and Antioxidant Activities
- Advanced Drug Delivery Systems
- Photoreceptor and optogenetics research
- Enzyme Catalysis and Immobilization
- Supramolecular Chemistry and Complexes
- Polymer Surface Interaction Studies
- Protein Interaction Studies and Fluorescence Analysis
- Bone Tissue Engineering Materials
- Polymer crystallization and properties
- Plant biochemistry and biosynthesis
- Advanced Polymer Synthesis and Characterization
- Polydiacetylene-based materials and applications
- Diatoms and Algae Research
- Process Optimization and Integration
- Thermodynamic properties of mixtures
- Graphene and Nanomaterials Applications
Universidade Federal do Rio de Janeiro
2021-2024
Universidade Federal de Santa Catarina
2015-2021
Max Planck Institute for Polymer Research
2019-2020
Abstract Bottom‐up synthetic biology is the science of building systems that mimic structure and function living cells from scratch. To do this, researchers combine tools chemistry, materials science, biochemistry to develop functional structural blocks construct cell‐like systems. The many strategies have been developed in recent decades enabled scientists engineer organelles essential functions behaviors natural cells. Examples include can synthesize their own ATP using light, maintain...
In the present work, nanoparticles of poly(methyl methacrylate-co-butyl acrylate) (P(MMA-co-BA)) and methacrylate-co-vinyl acetate) (P(MMA-co-VAc)) were synthesized by miniemulsion polymerization with in situ encapsulation praziquantel (PZQ) as a hydrophobic drug model. The reactions produced diameters ranging from 67 ± 0.5 to 130 1.1 nm, an efficiency at least 99%. glass transition temperatures (Tg's) copolymer successfully reduced 121.5 −9.3 °C absence PZQ 100.7 −13.7 presence encapsulated...
Many efforts have been devoted to bone tissue regenerate damaged tissues, and the development of new biocompatible materials that match biological, mechanical, chemical features required for this application is crucial. Herein, a collagen-decorated scaffold was prepared via electrospinning using synthesized unsaturated copolyester (poly(globalide-co-pentadecalactone)), followed by two coupling reactions: thiol-ene functionalization with cysteine further conjugation EDC/NHS chemistry...
Abstract When nanoparticles (NPs) are introduced to a biological fluid, different proteins (and other biomolecules) rapidly get adsorbed onto their surface, forming protein corona capable of giving the NPs new “identity” and determine fate. Protein–nanoparticle conjugation can be used in order promote specific interactions between living systems nanocarriers. Non‐covalent conjugates less stable more susceptible desorption media, which makes development engineered nanoparticle surfaces by...
Poly(ε-caprolactone) (PCL) is commonly used in devices for tissue reconstruction due to its biocompatibility and suitable mechanical properties. However, high crystallinity hydrophobicity do not favor cell adhesion difficult polymer bioresorption. To improve these characteristics, the development of engineered scaffolds regeneration, based on poly(globalide-co-ε-caprolactone) (PGlCL) covalently bonded with N-acetylcysteine (PGlCL-NAC) was proposed. The were obtained from blends PCL...
Superparamagnetic iron oxide nanoparticles (SPIONs) have their use approved for the diagnosis/treatment of malignant tumors and can be metabolized by organism. To prevent embolism caused these nanoparticles, they need to coated with biocompatible non-cytotoxic materials. Here, we synthesized an unsaturated copolyester, poly (globalide-co-ε-caprolactone) (PGlCL), modified it amino acid cysteine (Cys) via a thiol-ene reaction (PGlCLCys). The Cys-modified copolymer presented reduced...
Nanomaterials, such as magnetic nanoparticles have attracted significant attention of medical area due to their capacity improve the performance immunoassays. Therefore aim this work was study bovine serum albumin (BSA) conjugation in superparamagnetic (MNPs)/poly(methyl methacrylate) (PMMA) with further characterization and application enzyme-linked immunosorbent (ELISA) assay. The successful BSA MNPs- PMMA confirmed by several techniques, including light scattering, zeta potential,...
Polymersomes are synthetic vesicles that mimic the architecture of cellular compartments such as cell membrane and organelles. These biomimetic facilitate creation cell‐like chemical systems, including microreactors However, construction hierarchical multi‐compartment systems remains challenging typically requires encapsulation pre‐formed within a host compartment. Here, we report formation multicompartment polymersomes with vesicle‐in‐vesicle achieved through self‐division induced by short...
Polymersomes are synthetic vesicles that mimic the architecture of cellular compartments such as cell membrane and organelles. These biomimetic facilitate creation cell‐like chemical systems, including microreactors However, construction hierarchical multi‐compartment systems remains challenging typically requires encapsulation pre‐formed within a host compartment. Here, we report formation multicompartment polymersomes with vesicle‐in‐vesicle achieved through self‐division induced by short...
A Chia (Salvia hispanica) é uma planta cultivada nas Américas do Sul e Central, cuja semente fonte de antioxidantes naturais ácidos graxos essenciais. O presente estudo avaliou a obtenção extratos torta chia, subproduto proveniente da extração óleo chia. Foram aplicadas técnicas baixa pressão como em soxhlet (SOX), ultrassom (US) maceração (MAC) utilizando etanol, hexano acetato etila solventes, para comparar com o processo alta realizado por supercrítica (ESC). As ESC foram realizadas...