A5018578457- Extracellular vesicles in disease
- Bacterial Infections and Vaccines
- Cardiovascular Disease and Adiposity
- Microbial infections and disease research
- Pediatric Hepatobiliary Diseases and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Liver Disease and Transplantation
- Amoebic Infections and Treatments
- Cancer Immunotherapy and Biomarkers
- Liver Disease Diagnosis and Treatment
- Immune cells in cancer
- Gut microbiota and health
Université d'Angers
2020-2023
Université Bretagne Loire
2020-2023
Inserm
2020-2023
Montreal Clinical Research Institute
2023
Laboratoire Stress Oxydant et Pathologies Métaboliques
2020
Mycoplasmoses animales
2018
Université Claude Bernard Lyon 1
2018
VetAgro Sup
2018
The role of extracellular vesicles (EVs) from faeces (fEVs) and small circulating EVs (cEVs) in liver diseases such as non-alcoholic fatty (NAFLD) steatohepatitis (NASH) has not been demonstrated. fEVs cEVs healthy donors, NAFLD NASH patients were isolated characterized. effects evaluated intestinal, endothelial, Kupffer stellate cells. Non-muscular myosin light chain kinase (nmMLCK) deficient mice used vivo. Bacterial origins analysed by 16s rDNA gene sequencing. composed prokaryotic...
Release of extracellular vesicles (EV) by Gram-negative and positive bacteria is being frequently reported. EV are nano-sized, membrane-derived, non-self-replicating, spherical structures shed into the environment that could play a role in bacteria-host interactions. Evidence production belonging to class Mollicutes, which wall-less, mainly restricted genus Acholeplasma scanty for Mycoplasma comprises major human animal pathogens. Here release six (sub)species clinical importance was...
Rationale: Metabolic syndrome (MetS) is a cluster of interrelated risk factors for cardiovascular diseases and atherosclerosis. Circulating levels large extracellular vesicles (lEVs), submicrometer-sized released from plasma membrane, MetS patients were shown to induce endothelial dysfunction, but their role in early stage atherosclerosis on vascular smooth muscle cells (SMC) remain be fully elucidated. Objective: To determine the mechanisms by which lEVs lead progression setting MetS....