Geny Fierros-Zárate

ORCID: 0000-0002-6582-1489
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • interferon and immune responses
  • Helicobacter pylori-related gastroenterology studies
  • Eosinophilic Esophagitis
  • Cytokine Signaling Pathways and Interactions
  • Galectins and Cancer Biology
  • Bacteriophages and microbial interactions
  • Immunotherapy and Immune Responses
  • Listeria monocytogenes in Food Safety
  • Herpesvirus Infections and Treatments
  • RNA Interference and Gene Delivery
  • HIV/AIDS Research and Interventions
  • Hepatitis B Virus Studies
  • Advanced biosensing and bioanalysis techniques
  • Reproductive tract infections research
  • HIV Research and Treatment
  • T-cell and Retrovirus Studies
  • Genital Health and Disease
  • Identification and Quantification in Food
  • Virus-based gene therapy research
  • Salmonella and Campylobacter epidemiology

Instituto Nacional de Salud Pública
2001-2024

The Helicobacter pylori infection of gastric mucosa is one the most common infectious diseases and associated with a variety clinical outcomes, including peptic ulcer disease cancer. pylori-induced damage to mucosal cells controlled by bacterial virulence factors, which include VacA CagA. Outer membrane vesicles are constantly shed bacteria can provide an additional mechanism for pathogenicity releasing non-secretable factors then interact epithelial cells. present report shows that external...

10.1111/j.1574-6968.2006.00305.x article EN FEMS Microbiology Letters 2006-06-15

Cervical cancer is the second most common cause of death from in women worldwide, and development new diagnostic, prognostic, treatment strategies merits special attention. Many efforts have been made to design drugs develop immunotherapy gene therapy treat cervical cancer. HPV genotyping has potentially valuable applications triage low-grade abnormal cytology, assessment prognosis followup intraepithelial neoplasia, for invasive It known that during associated with infection, a cascade...

10.1155/2013/912780 article EN cc-by Obstetrics and Gynecology International 2013-01-01

Salmonella enterica non-typhoidal is a major contributor to diarrheal diseases, with over 2600 serovars identified across diverse environments. In Mexico, Newport and Anatum have shown marked increase, especially in foodborne disease, posing public health problem. We conducted cross-sectional study from 2021 2023 using active epidemiological surveillance assess contamination ground beef pork at butcher shops nationwide. It involved isolation, phenotypic antimicrobial resistance, comparative...

10.3390/microorganisms12122485 article EN cc-by Microorganisms 2024-12-03

Interferon tau (IFN-τ) is a promising alternative antiviral and immunotherapeutic agent in wide variety of diseases including infectious, neurodegenerative, autoimmune cancer due to its low toxicity comparison with other type I interferon´s.The objective our study was established the effect bovine IFN-τ on human (SiHa) murine (BMK-16/myc) cells transformed HPV 16 evaluates antitumor tumor model positive.We determine that has antiproliferative effects, pro-apoptotic activity induces...

10.7150/jca.15502 article EN cc-by-nc Journal of Cancer 2016-01-01

Human papillomavirus (HPV) is a DNA virus that infects epithelial cells and has been implicated in the development of cervical cancer.Few therapeutic strategies have designed for treatment intraepithelial neoplasia, precursor cancer.In these early stages, HPV E2 protein most important viral factor involved gene expression plays crucial roles during vegetative cycle cells.Papillomavirus binds specifically to palindromic ACCN 6 GGT sequences, referred as binding sites (E2BS), which are...

10.7150/jca.15536 article EN cc-by-nc Journal of Cancer 2016-01-01

The mechanisms of signal transduction by interferon-tau (IFN-τ) are widely known during the gestation ruminants.In trophoblast cells, IFN-τ involves activation JAK-STAT pathway, and it can have effects on other cell types, such as tumor cells.Here we report that HPV16-positive BMK-16/myc treated with ovine IFN-τ, results in canonical non-canonical pathway.The MAPK signaling pathway was activated, detected proteins MEK1, MEK2, Raf1, STAT3, STA4, STAT5 STAT6.Moreover, induced expression MHC...

10.7150/jca.33527 article EN cc-by-nc Journal of Cancer 2020-01-01
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