A5003273804- Pesticide Exposure and Toxicity
- Bacillus and Francisella bacterial research
- Disaster Response and Management
- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Health and Conflict Studies
- Bacteriophages and microbial interactions
- Esophageal and GI Pathology
- Chemical Safety and Risk Management
- Hepatitis C virus research
- Microbial Inactivation Methods
- Poisoning and overdose treatments
- Ovarian function and disorders
- Hepatitis B Virus Studies
- Chemotherapy-induced organ toxicity mitigation
- Radiation Dose and Imaging
- Carcinogens and Genotoxicity Assessment
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Viral Infections and Outbreaks Research
- Hernia repair and management
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Intestinal and Peritoneal Adhesions
- Selenium in Biological Systems
University of Health Science
2024-2025
Sağlık Bilimleri Üniversitesi
2017-2024
Turkish Armed Forces
2004-2018
Gülhane Askerî Tıp Akademisi
2006-2012
Military Medical Academy
2009-2012
Palmetto Hematology Oncology
2009
Milli Savunma Üniversitesi
2007
Sulphur mustard (SM) is an highly toxic and vesicant chemical weapon that was used in various military conflicts several times the history. The severity of ocular, dermal, pulmonary symptoms may appear following a characteristic asymptomatic period are depending on SM concentration exposure duration. aim this study to present clinical features share intensive care unit (ICU) experiences for medical management gas victims.Thirteen Free Syrian Army soldiers near Al-Bab region North Syria were...
Abstract Objectives The Pasteur effect in cellular energy metabolism is defined as the switch to anaerobic glycolysis due alterations ambient oxygen concentration or inhibition of electron transport chain (ETC) and oxidative phosphorylation. This study aimed determine Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection on leukocytes among Disease 2019 (COVID-19) patients at various stages. Methods A total 90 cases were analyzed asymptomatic, mild, moderate, severe COVID-19...
Although some information is available regarding immune activation in familial Mediterranean fever (FMF), little known about either peripheral blood T cell marker expression or the proliferative response to phytohaemagglutinin (PHA). In present study, we aimed investigate percentages of lymphocyte subsets, cellular markers (CD25, CD69, HLA-DR), PHA and serum levels soluble interleukin-2 receptor (sIL-2R) interleukin (IL)-10 patients with FMF. Forty FMF were enrolled into study. Control...
Aim. There are no studies that examine the circulating acylation-stimulating protein (ASP) levels in patients with polycystic ovary syndrome (PCOS). The present study was designed to determine ASP PCOS and evaluate effect of metformin on plasma fasting concentrations.Methods. Twenty women 20 healthy controls matched for age body mass index (BMI) were included study. We determined other biochemical parameters before after treatment.Results. Baseline ASP, complement 3 (C3), waist-to-hip ratio...
Among the most readily available chemical warfare agents, sulfur mustard (SM), also known as gas, has been widely used weapon. SM causes debilitating effects that can leave an exposed individual incapacitated for days to months; therefore delayed toxicity is of much greater importance than its ability cause lethality. Although not fully understood, acute related reactive oxygen and nitrogen species, oxidative stress, DNA damage, poly(ADP-ribose) polymerase (PARP) activation energy depletion...
Disaster is defined as the holistic state of natural or human-induced events that develop suddenly, whose controllability requires a systematic approach, which interrupts stops social life and causes loss life, property often cannot be overcome with local capacity. Biological disasters can well naturally infectious diseases epidemiological emergencies. Considering potential 21st century, biological have played role in influenza infections such Swine Flu (H1N1), Bird Influenza (H5N1),...
Chemical warfare agents are toxic weapons and emergency prehospital medical care providers should be well prepared, trained, equipped to give response. Personnel need aware of the following issues regarding management a chemical attack, event recognition, incident command control, safety protection, decontamination, isolation area (hot zone, warm cold zone), sampling detection, psychological management, communication, triage, treatment, transportation, recovery activities fatality...
A gas chromatographic-mass spectrometric method was developed, validated and demonstrated by measuring the levels of nitrogen mustard hydrolysis products in urine collected from dosed rats. The recovery values for trimethylsilyl derivatives EDEA MDEA are between 82-95% 88-112%, respectively. In vivo studies performed using three different doses (0.5 mg/kg, 1.0 2.0 mg/kg) HN2 base mustard. concentrations were 43.1-232.2 ng/mL. limit detection (S/N = 3) 2.5 ng/mL 1.6 MDEA, respectively,...
Background: Sulfur mustard (SM) is a vesicant chemical warfare agent. Ocular, dermal, and respiratory systems are the primary targets of SM exposure. The aims this study were to perform quantitative analysis β-lyase metabolites as 1,1'-sulfonylbis[2-(methylthio) ethane] (SBMTE) in urine samples casualties investigate relationship between measured SBMTE levels severity characteristic symptoms poisoning.Methods: A bioanalytical method which based on titanium (III) chloride reduction was...
Because of spore formation, Bacillus anthracis is considered the most resistant biological warfare agent known. The present study aimed to assess and compare well-known decontamination routes inactivate spores on daily-use environmental tools contaminated previously. To simulate agent, atrophaeus was used. Various samples (such as tile, fabric clothing, wood, protective suit, glass, paper, soil, water, plastic, metal) that may be after a incident were used test carriers inoculated with B....
Purpose: The aim of this study was to compare the medical chemical, biological, radiological, and nuclear CBRN awareness emergency healthcare professionals from two different centres.Methods: survey conducted among 67 including physicians, nurses, technicians, paramedics departments cities. A questionnaire that designed in order evaluate demographic data age, gender, job description, education level knowledge/experience about filled by participants during face-toface interviews. All were...
Mustard, a vesicant warfare agent, has cytotoxic, mutagenic, and cytostatic effects via alkylation of DNA inhibition replication. Since symptoms appear following latent period, it can cause some subacute chronic to occur delay in the treatment. Therefore, main approach should be use protective preparation reduce skin toxicity. Thus, this study was conducted guinea pigs (350-400 g) shaved areas 10 x cm. Mechlorethamine HCl (100 mg), nitrogen mustard derivative, ethanol applied by spraying on...
Abstract Introduction: During the 2004 North Atlantic Treaty Organization (NATO) Summit, essential counter-measures, including medical preparedness, were taken to cope with any suspected terrorist case or events use of chemical biological (CB) weapons.The Summit was held in Istanbul, a city that bridges two continents, and involved participation many Heads State, Prime Ministers, Defense Ministers from 26 NATO countries. Methods: First responders, Chemical, Biological, Radiological, Nuclear...