A5012361702- COVID-19 Clinical Research Studies
- Human Health and Disease
- COVID-19 Impact on Reproduction
- Inflammasome and immune disorders
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Virology and Viral Diseases
- Kawasaki Disease and Coronary Complications
- Healthcare Systems and Public Health
- Hypothalamic control of reproductive hormones
- Estrogen and related hormone effects
- Business Strategy and Innovation
- COVID-19 and Mental Health
- Immunodeficiency and Autoimmune Disorders
- Viral Infections and Vectors
- Cytokine Signaling Pathways and Interactions
- Vaccine Coverage and Hesitancy
- Reproductive System and Pregnancy
- Pediatric health and respiratory diseases
- Telomeres, Telomerase, and Senescence
- Livestock and Poultry Management
- Syphilis Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- Thyroid Disorders and Treatments
Kyiv City Clinical Oncology Center
2018-2023
Bogomolets National Medical University
2019-2022
University of Warmia and Mazury in Olsztyn
2018
The coronavirus infection (COVID-19) pandemic has seen a progressive increase in childhood morbidity worldwide. Continuous mutation of the SARS-CoV-2 virus causes wave-like course COVID-19 pandemic, which is characterized by an undulating and predominance different variants virus. There are many reports that clinical picture may vary depending on circulating strain [7-11, 13-16]. Based this, we decided to analyze evaluate presence pattern between epidemic characteristics prevailing...
Background. Studying COVID-19 prevalence among children is important for constant monitoring of the epidemiological situation, determination most vulnerable categories children, and planning preventive measures. The aim our research was a retrospective study Ukraine in 2020. Materials methods. A from different regions conducted, based on official statistical reports Ministry Health Ukraine. measured as number cases per 100,000 children. Results. Among population Ukraine, with confirmed...
Coronavirus disease (COVID-19), which was first recorded in China December 2019, quickly spread to other countries and a short period of time, the local outbreak escalated into pandemic. There are significantly more cases COVID-19 morbidity mortality European than East Asia, where detected. Such population differences unique, especially for SARS-CoV-2 due both socio-behavioral features gene pool different countries. For infectious diseases, such as COVID-19, an important point is genetic...
Актуальність. Незважаючи на наявність безпечної й ефективної вакцини, кір залишається однією з головних причин смерті серед дітей у всьому світі. У 2017–2018 роках різних країнах світу та в нашій країні зокрема спостерігається зростання кількості хворих кір. В Україні 41-й тиждень від початку 2018 року захворіли 33 165 осіб, яких 13 184 дорослі 19 981 дитина. Метою роботи було вивчення клінічних особливостей кору під час спалаху рр. Матеріали методи. Були досліджені діти, які проходили...
In December 2019, the Chinese city of Wuhan reported first cases pneumonia from a new type beta coronavirus named SARS-CoV-2. early days COVID-19 outbreak, paediatric patients were thought to be immune virus; however, further studies have shown people all ages susceptible virus.
Background The SARS-CoV-2 virus, the causative agent of coronavirus disease (COVID-19), mutated during its replication and spread among population. These mutations led to new viral variants, which differed in their characteristics manifestations, contributing wave-like progression COVID-19. Centers for Disease Control Prevention classified variants based on public health risk include interest such as ? ?, concern including high consequence, being monitored. Objective To conduct a comparative...
Determining the levels of effectiveness in accessibility medical services and financial provision care to population within framework clustered structures a capable network health institutions requires systematic comprehensive approach solving this problem. With help listed actions, an determining is formed, which can become useful tool development theoretical methodological principles direction. The analysis conducted using such allows not only assess existing system, but also provides...
In this study, we tested the hypothesis that modulation of endogenous gonadotropin-releasing hormone (Gnrh) neuronal network activity alters mRNA expression nuclear receptor subfamily 5 group A member 1 (Nr5a1), through one component Wnt pathway signaling - catenin beta (Ctnnb1) (its co-activator), and its co-repressor 0, B (Nr0b1) in female rat pituitary gland vivo. Adult ovariectomized rats were given a serial infusion Gnrh, kisspeptin-10, Gnrh + antagonist (Antide), or kisspeptin-10...
Purpose - to characterize the epigenetic factors of COVID-19 in women childbearing age, residents Kharkiv region who have had coronavirus infection, identified as a result clinical and epidemiological studies. Materials methods. This research investigates potential risk for onset progression age region. An original, comprehensive questionnaire designed capture wide range health socio-biological was disseminated among 100 contracted virus. Follow-up examinations interviews were conducted with...
<b>Background:</b> COVID-19 caused by SARS-CoV-2 remains a major public health problem. Previous studies demonstrated that interferon lambda 4 (IFNL4) has antiviral activity against viral infections of the upper respiratory tract, including some coronaviruses. However, we have limited data about association these genetic variants with infection, especially among children recurrent (RRI). <b>Objectives:</b> The aim this study was to identify relationship between ss469415590 polymorphism gene...
Research objective: to determine the risk factors for spread of coronavirus infection among women fertile age.Materials and methods. Authors analyzed medical records (case histories questionnaires) 60 age who were treated disease. After analysis social divided into groups. Analysis disease was determined by calculating odds ratio according Wald at p < 0.05.Results. Evaluation COVID-19 chances depending on nature work different ages showed that with intense increases 2.5 times in group up...
Доброякісний рецидивуючий менінгіт Молларе — рідкісне захворювання, що характеризується повторними епізодами асептичного менінгіту зі спонтанним одужанням. Аналіз опублікованих випадків свідчить, захворювання переважно зустрічається в дорослих. Існують лише поодинокі повідомлення про дітей. У даній статті наведений клінічний випадок у хворої, якої спостерігалося 5 епізодів починаючи з 3-річного віку.
Актуальність. Пандемія коронавірусної хвороби COVID-19, спричинена новим коронавірусом SARS-CoV-2, на сьогодні є глобальною проблемою, однак досить обмеженими дані щодо особливостей перебігу інфекції COVID-19 у дітей. Мета: провести узагальнюючий аналіз демографічних, епідеміологічних і клінічних дітей різного віку з різних регіонів України. Матеріали та методи. З дотриманням принципів біоетики проведено багатоцентрове ретроспективне відкрите когортне дослідження 669 випадків дітей,...
<b>Introduction:</b> clinical features for SARS-CoV-2 of pediatric patients is limited and requires further research. <b>Objectives:</b> The aim our study was to determine describe the clinical, demographic, epidemiological of COVID-19 hospitalized children in Ukraine. <b>Materials methods:</b> A retrospective 130 patients, age from 1 month 18 years Kyiv Children9s Clinical Hospital Infectious Diseases diagnosed with laboratory-confirmed carried out. <b>Results:</b> majority presented a...
Aim. The purpose of this study was to find out the clinical and epidemiological features measles in children during outbreak 2017–2018.Materials methods. A retrospective 230 case histories suffering from hospitalized Kyiv Children's Clinical Hospital conducted two epidemic outbreaks 2005–2006 2017–2018.Results. In 2017–2018, majority with (62.9 %) were school age children. Compared 2006, mean patients has increased significantly, proportion first year life significantly decreased percentage...
Purpose - to study the features of vitamin D status and effect D3 supplementation on 25(OH)D in serum school-age children with COVID-19, taking into account genotype rs2228570 polymorphism receptor (VDR) gene. Materials methods. The pilot, prospective, open-label included 36 schoolchildren aged 9-16 who experienced asymptomatic (12 children) mild / moderate (24 COVID-19. In all were studied content blood its dynamics under influence 1000 IU per day for 12 weeks, genotypes frequency...
<b>Introduction:</b> Recurrent respiratory infections (RRI) represent a widespread condition in childhood. Now we have limited data about the course of SARS-CoV-2 infection among children with RRI. <b>Objectives:</b> The aim our study was to describe clinical features COVID-19 RRI comparison occasionally ill Ukraine. <b>Materials and methods:</b> Study 150 pediatric patients from different regions Ukraine, aged 4 18. Group 1 – 79 (52,6%) more than eight episodes per year, group 2 - 71...