A5004622115- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Neurological Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Hormonal Regulation and Hypertension
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Respiratory and Cough-Related Research
- Pediatric health and respiratory diseases
- Biochemical Acid Research Studies
- Human Health and Disease
- Heart Rate Variability and Autonomic Control
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Lipoproteins and Cardiovascular Health
- Nutritional Studies and Diet
- Peripheral Artery Disease Management
- Fatty Acid Research and Health
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Macrophage Migration Inhibitory Factor
- Medical Imaging Techniques and Applications
- Sodium Intake and Health
- Probiotics and Fermented Foods
Bogomolets National Medical University
2015-2025
Duke Medical Center
2016
Clinical Research Institute
2016
National University
2009
The aim – to investigate the clinical features, nature of daily rhythm blood pressure, target organ damage and psycho-emotional state patients with hypertension who were direct participants in military conflict Ukraine.Materials methods. analysis features course was carried out 58 men hostilities Ukraine. Patients divided into groups depending on time onset hypertension, presence or absence signs anxiety depression according HADS hospital scale, previous acubarotrauma. Objective condition,...
Aim The prevalence of ischemia with nonobstructive coronary artery disease increases all over the world which is confirmed by results angiographies. However, physicians diagnose only tip iceberg. latter predominantly connected several factors, namely atypical nonspecific silent manifestation, course disease, high cost investigational procedures for diagnosis establishment, and low awareness medical specialists regarding abovementioned nosology. In current paper, we aimed to propose algorithm...
Multifocal atherosclerosis (MAS) remains one of the key problems modern medicine, despite advances in primary and secondary prevention myocardial infarction (MI) ischemic stroke (IS). MAS worsens prognosis increases risk atherosclerotic plaque (AP) destabilization, especially under influence matrix metalloproteinases (MMPs). Activation sympatho-adrenal serotonergic systems with release dopamine serotonin also plays a significant role pathogenesis this process, influencing regulation vascular...
Patients with combined coronary heart disease and diabetes mellitus make up a growing segment of the population require com¬prehensive treatment approach. concurrent have worse projection. Under these conditions, incidence recurrent myocardial infarction, early disability due to complications, risk death are increased. Therefore, priority task is find ways optimize drug this category patients, taking into account impact drugs on pathogenetic links progression development cardiovascular...
Aim: To investigate the serotonin and von Willebrand factor (vWF) concentrations among unstable angina (UA) patients without with progression toward myocardial infarction (outcome) to assess utility of both as prognostic markers UA complications.
 Materials methods: In observational cohort study, we recruited 103 ischemic heart disease (the median age 65.0 (59.0-69.0) years, 45 females (43.7%)). After full set investigations including high sensitive Troponin I test 28-day follow-up...
Objective: Despite significant advances in the study of pathogenesis, clinical picture and treatment arterial hypertension (AH), role dopaminergic system obese patients remains insufficiently studied. Aim: To evaluate effectiveness use D2 receptor agonists with (AH) nutritional-constitutional obesity (NCO) 3rd degree. Design method: We examined 151 aged 30-60 years (65 men, 86 women) AH NCO. The control group (CG) consisted 78 hypertensive patients. Daily monitoring blood pressure (BP), body...
The aim is to observe and compare the main factors that can improve gut microbiota composition. Materials methods. literature study research was performed in PubMed Google Scholar electronic databases. We assessed more than 300 studies, data from 65 of which were included this review. They are presented three tables: nonpharmacological influence on composition, drugs impact microbiota, medicines prescribed for correction. Results. On one hand, non-pharmacological methods improvement safest...
The aim: To check changes of gut microbiota composition and its metabolites in atherosclerosis (AS) patients with or without atrial fibrillation (AF) special connections between them important clinic laboratory features investigated groups. Materials methods: 300 were investigated. All divided into 3 groups: control group (CG) – 27 AS arrhythmias; mean 149 but comparable 124 AF paroxysm. By 16-S rRNA sequencing was checked composition. level trimethylamine-N-oxide (TMAO), trimethylamine...
At present, antiplatelet agents have been widely used in the treatment of cardiovascular diseases. In this article, based on data numerous clinical studies, effectiveness use inhibitor platelet aggregation Cilostazol is demonstrated, a medication, which by some its features exceeds efficiency acetylsalicylic acid.The uniqueness drug fact that only with proven atherosclerosis peripheral arteries, intermittent claudication. Based results number randomized trials and meta-analysis data, are...
The article presents a specific clinical case and literature data on rare finding in the heart cavity — Lambl’s fila ments. Histologically, these are cells of fibroelastic tissue covered with stroma epithelial layer. They do not have vascular sheath, so they devoid granulation tissue. growths occur both their own prosthetic valves. Very rarely, threads can also be seen areas other than valves such as papillae, atria, chords. These lesions echocardiogram accidentally or connection serious...
The article provides brief data on the renin-angiotensin system, main effects of angiotensin II caused by stimulation receptors type 1 (AT1) and 2 (AT2). Classification AT1-receptor blockers (ARB), their clinical effects, antihypertensive efficacy interaction with some medications as well impact patients` prognosis are given. Information about Irbesartan one representatives ARB class is provided.
У статті проаналізовано результати вивчення впливу гіпотензивної терапії з використанням агоністів дофамінових рецепторів на клініко-гемодинамічні та нейрогуморальні показники у хворих артеріальною гіпертензією із супутнім ожирінням. Особливу увагу приділено такому патогенетичному чиннику, як дофамін, його взаємозв’язкам ренін-ангіотензин-альдостероновою системою, вазодилатаційною функцією ендотелію, дія яких спрямована регуляцію артеріального тиску формування і прогресування ожиріння.
Background. Myocarditis is one of the most dangerous complications both acute phase COVID-19 and long COVID-19, with a rather heterogeneous clinical presentation that ranges from asymptomatic to life-threatening. The diverse high risk further complications, on hand, good prognosis in case appropriate treatment, other demand great attention doctors.
 Case Report. We report 27-year-old male presented cardiologist complaints dyspnea, chest pain, palpitation occurred eight months after mild...
Вивчали жирнокислотний склад тригліцеридів плазми крові методом газорідинної хроматографії, динаміку сегмента ST, порушення серцевого ритму добового моніторування електрокардіографії у хворих з нестабільною стенокардією (прогресуюча) і вплив на них лікування використанням статинів. Виявлені виражені якісні прогресуючою проявлялися збільшенні суми насичених та зменшенням ненасичених жирних кислот. Високий терапевтичний ефект симвастатину аторвастатину можна пояснити визначеним сильним...