A5066620982- Neuroinflammation and Neurodegeneration Mechanisms
- Ginseng Biological Effects and Applications
- MicroRNA in disease regulation
- Galectins and Cancer Biology
- Circular RNAs in diseases
- interferon and immune responses
- Extracellular vesicles in disease
- Tryptophan and brain disorders
- Ubiquitin and proteasome pathways
Guangzhou University of Chinese Medicine
2025
Guangzhou Medical University
2024
State Key Laboratory of Respiratory Disease
2024
Hebei Medical University
2022
Second Hospital of Hebei Medical University
2022
Ginseng, known as the "king of herbs," has long been used in traditional Chinese medicine due to its beneficial properties, including anti-aging, anti-inflammatory, and anti-apoptotic effects. Ginsenosides, active compounds ginseng, have shown promise treating neurodegenerative diseases such Alzheimer's disease (AD). This study investigates therapeutic potential Ginsenoside Ro underlying mechanisms AD treatment. In this study, male APP/PS1 transgenic mice were divided into five groups...
Brahma-related gene 1 (BRG1) has been implicated in the repair of DNA double-strand breaks (DSBs). Downregulation BRG1 impairs DSBs leading to accumulation double-stranded (dsDNA). Currently, role diabetic cardiomyopathy (DCM) not clarified. In this study, we aimed explore function and molecular by which regulates DCM using mice cell models. We found that was downregulated cardiac tissues cardiomyocytes cultured with high glucose palmitic acid (HG/PA), accompanied dsDNA activation cyclic...