José Ignacio Santos

ORCID: 0000-0002-6653-043X
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About
Contact & Profiles
Research Areas
  • Child Nutrition and Water Access
  • Viral gastroenteritis research and epidemiology
  • Vaccine Coverage and Hesitancy
  • Evolutionary Game Theory and Cooperation
  • Pneumonia and Respiratory Infections
  • Influenza Virus Research Studies
  • Opinion Dynamics and Social Influence
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial Infections and Vaccines
  • Advanced Welding Techniques Analysis
  • Welding Techniques and Residual Stresses
  • Virology and Viral Diseases
  • Antibiotic Resistance in Bacteria
  • Neonatal and Maternal Infections
  • Parasites and Host Interactions
  • Streptococcal Infections and Treatments
  • Non-Destructive Testing Techniques
  • Archaeology and ancient environmental studies
  • Vitamin C and Antioxidants Research
  • Pleistocene-Era Hominins and Archaeology
  • Antibiotic Use and Resistance
  • Child and Adolescent Health
  • Complex Network Analysis Techniques
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Respiratory viral infections research

Universidad de Burgos
2014-2024

Universidad Nacional Autónoma de México
2002-2024

Federal Institute of Education, Science and Technology Alagoas
2023

Hospital General de México
2001-2020

George Washington University
2019

World Health Organization Regional Office for the Americas
2019

Milken Institute
2019

Center for Global Health
2019

Hospital Infantil de México Federico Gómez
1993-2008

Mexican Social Security Institute
2008

The increasing geographical spread and disease incidence of arboviral infections are among the greatest public health concerns in Americas. region has observed an trend dengue last decades, evolving from low to hyperendemicity. Yellow fever also intensified this period, expanding sylvatic-restricted activity urban outbreaks. Chikungunya started spreading pandemically 2005 at unprecedented pace, reaching Americas 2013. following year, Zika emerged with explosive outbreak, carrying devastating...

10.2105/ajph.2018.304849 article EN American Journal of Public Health 2019-01-24

In a multicenter study, hepatitis A virus (HAV) seroprevalence was surveyed in six countries Latin America which 12,000 subjects were stratified for age. The highest rates of recorded the Dominican Republic (89.0%) and Mexico (81.0%), with lower Brazil (64.7%), Chile (58.1%), Venezuela (55.7%), Argentina (55.0%). HAV children between 1 5 years age less than 50%, except Republic. 5-10-year-old group, have also decreased compared previous reports. This suggests that epidemiology is shifting...

10.4269/ajtmh.1999.61.825 article EN American Journal of Tropical Medicine and Hygiene 1999-11-01

Abstract Background Malnutrition in children can be a consequence of unfavourable socioeconomic conditions. However, some families maintain adequate nutritional status their despite living poverty. The aim this study was to ascertain whether family-related factors are determinants stunting young Mexican extreme poverty, and these differ between rural or urban contexts. Methods A case-control conducted one poverty level areas Mexico. Cases comprised stunted aged 6 23 months. Controls were...

10.1186/1471-2458-4-57 article EN cc-by BMC Public Health 2004-11-30

Seventy-six children < or =2 years old were prospectively followed for 1 year in a peri-urban community of Mexico City to determine asymptomatic infection and acute diarrhea associated with diarrheagenic Escherichia coli pathotypes (DEPs). By use pathogen-specific multiplex PCR, DEPs sought 795 stool samples, which 125 (16%) positive DEP; these, 4 represented shedding episodes parasite coinfections. Most single-DEP infections (85/117) (P 0.001), the 32 DEP episodes, 41% atypical...

10.1128/jcm.01166-08 article EN Journal of Clinical Microbiology 2008-11-20

Project control is a crucial phase within project management aimed at ensuring —in an integrated manner— that the objectives are met according to plan. Earned Value Management —along with its various refinements— most popular and widespread method for top-down control. For under uncertainty, Monte Carlo simulation statistical/machine learning models extend earned value framework by allowing analysis of deviations, expected times costs during progress. Recent advances in explainable machine...

10.1016/j.cie.2023.109261 article EN cc-by Computers & Industrial Engineering 2023-04-23

A child with infant botulism became apneic and died while receiving ampicillin gentamicin therapy. As aminoglycosides have been implicated in the induction and/or exacerbation of neuromuscular blockade, we used an animal model to test hypothesis that potentiate blockade botulinum toxin. In range aminoglycoside doses utilized these experiments, both tobramycin enhance impairment death toxin-exposed mice. These results support recently published clinical observations may weakness caused by...

10.1542/peds.68.1.50 article EN PEDIATRICS 1981-07-01

OBJECTIVE. Gastrointestinal parasites continue to be an important cause of morbidity and stunting among children in developing countries. We evaluated the effect vitamin A zinc supplementation on infections by Giardia lamblia, Ascaris lumbricoides, Entamoeba histolytica. METHODS. randomized, double-blind, placebo-controlled trial was conducted 707 who were 6 15 months age from periurban areas Mexico City, Mexico, between January 2000 May 2002. Children, assigned receive either every 2...

10.1542/peds.2006-2187 article EN PEDIATRICS 2007-10-01

ABSTRACT The identification of immune response mechanisms that contribute to the control diarrheal disease in developing countries remains an important priority. We addressed role fecal chemokines and cytokines resolution Escherichia coli Giardia lamblia infections. Stools collected from 127 Mexican children 5 15 months age enrolled a randomized, double-blind, placebo-controlled, vitamin A supplementation trial were screened for enteropathogenic (EPEC), enterotoxigenic E. (ETEC), . Fecal...

10.1128/iai.00767-09 article EN Infection and Immunity 2009-12-29

The seroprevalence of hepatitis B was investigated in over 12 000 subjects six countries Latin America: Argentina, Brazil, Chile, the Dominican Republic, Mexico, and Venezuela. Each study population stratified according to age, gender, socioeconomic status. Antibodies against core antigen (anti-HBc) were measured order determine infection. highest overall found Republic (21.4%), followed by Brazil (7.9%), Venezuela (3.2%), Argentina (2.1%), Mexico (1.4%), Chile (0.6%). In all an increase...

10.1590/s1020-49891999001100002 article EN Revista Panamericana de Salud Pública 1999-12-01

ABSTRACT Sixty-three children in periurban Mexico City were examined for the occurrence of asymptomatic norovirus (NoV) infection from June to August 1998. NoV was detected 48 161 stool specimens (29.8%), with 31 (49.2%) having at least one positive stool. Asymptomatic occurred commonly during summertime a Mexican pediatric population.

10.1128/jcm.00065-06 article EN Journal of Clinical Microbiology 2006-08-01

Journal Article Assessment of the Virulence Factors Group B Streptococci: Correlation with Sialic Acid Content Get access Ann O. Shigeoka, Shigeoka From Departments Pathology, Pediatrics, and Obstetrics Gynecology, University Utah School Medicine, Salt Lake City, Search for other works by this author on: Oxford Academic PubMed Google Scholar Neal S. Rote, Rote Jose I. Santos, Santos Harry R. Hill The Infectious Diseases, Volume 147, Issue 5, May 1983, Pages 857–863,...

10.1093/infdis/147.5.857 article EN The Journal of Infectious Diseases 1983-05-01

Este trabajo compara dos técnicas de modelado sistemas complejos: la simulación basada en agentes y dinámica sistemas. Esta comparación se lleva a cabo dentro del marco general proceso científico. Los autores concluyen que principal diferencia entre las metodologías encuentra el abstracción cada una ellas realiza para construir modelo formal partir sistema complejo observado. inicial extiende restantes etapas Finalmente, indican los principales factores propiedades generales un hacen u otra...

10.5944/empiria.16.2008.1391 article ES cc-by-nc-sa Empiria Revista de metodología de ciencias sociales 2008-10-02

Using an indirect immunofluorescence assay on stool samples, we found a 6.4% prevalence of cryptosporidiosis among 403 children less than five years age with acute diarrhea in Mexico City over one-year period. The was highest (11.4%) during the rainy summer months. Most Cryptosporidium parvum cases occurred infants one year age. more common malnourished (P < 0.05) and nonbreast-fed six months 0.01). Neither dwelling characteristics nor presence domestic animals at home were associated C....

10.4269/ajtmh.1997.56.254 article EN American Journal of Tropical Medicine and Hygiene 1997-03-01
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