A5018907352- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- Neurological disorders and treatments
- Pericarditis and Cardiac Tamponade
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Analog and Mixed-Signal Circuit Design
- Health Systems, Economic Evaluations, Quality of Life
- Radiopharmaceutical Chemistry and Applications
- Ion channel regulation and function
- Cardiovascular Function and Risk Factors
- Cardiac tumors and thrombi
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
Russian Scientific Center of Surgery
2015-2023
Ente Ospedaliero Cantonale
2023
Sechenov University
2023
Na Homolce Hospital
2015
Pacing remote from the latest electrically activated site (LEAS) in left ventricle (LV) may diminish response to cardiac resynchronization therapy (CRT). We tested whether proximity of LV pacing (LVPS) LEAS, determined by non-invasive three-dimensional electrical activation mapping [electrocardiographic Imaging (ECGI)], increased likelihood CRT response.Consecutive patients underwent ECGI and chest/heart computed tomography 6-24 months post-implant. Latest distance LVPS (dp) were assessed....
AimsThe aim of the present study was to estimate accuracy a novel non-invasive epicardial and endocardial electrophysiology system (NEEES) for mapping ectopic ventricular depolarizations.
Background The underlying mechanisms of Brugada syndrome (BrS) are not completely understood. Recent studies provided evidence that the electrophysiological substrate, leading to electrocardiogram abnormalities and/or ventricular arrhythmias, is located in right outflow tract ( RVOT ). purpose this study was examine epicardial and endocardial local unipolar electrograms by simultaneous noninvasive mapping patients with BrS. Methods Results Local were analyzed using a novel n oninvasive e pi‐...
Radiofrequency catheter ablation of atrial fibrillation (AF) is one the most complex procedures. Both patients and operators are exposed to scattered radiation. This study evaluated safety efficacy intracardiac echo (ICE)-guided pulmonary vein isolation (PVI) without fluoroscopy.We retrospectively analyzed data 481 consecutive with paroxysmal AF undergoing radiofrequency PVI CARTO 3 system (Biosense Webster, Diamond Bar, CA, USA). ICE-guided fluoroscopy CT/MRI integration (Nonfluoro group)...
The aim of this study was to assess the use a novel noninvasive epicardial and endocardial electrophysiology system (NEEES) for mapping ventricular arrhythmias. Eight patients (2 females, mean age 50 ± 17 years) with ischemic (n = 3) nonischemic 5) cardiomyopathy inducible arrhythmias during were enrolled. Noninvasive performed using NEEES based on body-surface electrocardiograms computed tomography imaging data. Arrhythmia patterns analyzed phase mapping. Macro-reentrant VT circuits...
Patients with atrial fibrillation (AF) routinely undergo different imaging modalities for the evaluation of left (LA) appendage to rule out thrombus prior AF ablation procedure. Recently, uninterrupted novel oral anticoagulants were introduced patients undergoing minimize peri-procedural thromboembolism risk. We performed a retrospective analysis evaluate safety rivaroxaban and whether transesophageal (TEE) or intracardiac echocardiography (ICE) is necessary ablation. Data from 332...
Background A novel noninvasive epicardial and endocardial electrophysiology system ( NEEES ) to identify electrical rotors focal activity in patients with atrial fibrillation AF was recently introduced. Comparison of data results from invasive mapping is lacking. Methods Six male (59 ± 11 years) persistent underwent cardiac the , which included creation isopotential phase maps. Then catheter using a PentaRay NAV CARTO 3 system. Signals acquired by were analyzed customized software that...
Accurate localization of the origin focal ventricular arrhythmias is a prerequisite to successful catheter ablation. However, arising from complex anatomic sites render mapping and ablation difficult. On 12-lead surface electrocardiography (ECG), QRS morphology may be difficult discern because their vicinity, in particular if right outflow tract, aortic sinus cusps, aortomitral continuity (AMC).
Tabled 1KEY TEACHING POINTS•Specific electrogram (EG) abnormalities may be identified by electrocardiographic imaging (ECGI) in the right ventricular outflow tract (RVOT) Brugada syndrome (BrS) patients even with normal surface electrocardiography.•Fractioned EG and ST segment elevation were found epicardium while only was endocardium of RVOT.•Phase mapping based on ECGI showed that excitation pattern underlying polymorphic tachycardia BrS can represented a single epicardial reentrant wave,...
Background: The outcomes of ventricular tachycardia (VT) ablation in patients with structural heart disease (SHD) are not ideal. High-power radiofrequency (RFA) may have a long-term beneficial effect this patient cohort.Objective: To evaluate the safety, early and efficacy high-power RFA for VT concomitant SHD multicenter prospective registry.Methods: Our study included total 63 (66,7% them were men; median age was 61.0 [51.0-66.5] years) ischemic drug-resistant who scheduled (50 W)....
to examine relationship between anatomical changes of the left ventricle (LV), dynamics velocity its volume modification, and blood flows in LV patients with mitral regurgitation (MR) before after surgical treatment.We included into this study 58 severe 3-4 degree MR (38 men, 20 women aged 24-69 [mean age 51±9] years) sinus rhythm (96 %) or atrial fibrillation (4 %). The control group 86 healthy volunteers, mean 39±7 years. Transthoracic echocardiographic studies were performed both groups...
Giant left atrium is a rare condition, with reported incidence of 0.3%, and mainly associated rheumatic mitral valve disease predominant regurgitation. has significant hemodynamic effects requires specific management in the most cases. We present an unusual case 65-year-old woman massive atrial enlargement accompanied by frequent right ventricular pacing, who was documented severe pacing-induced dyssynchrony.
Introduction: A novel non-invasive endo- and epicardial mapping system (NEEES) for identification of focal activity rotors in patients with atrial fibrillation (AF) was recently introduced. Comparisons NEEES data to results from invasive endocardial rotor is still lacking. Methods: 6 persistent AF (6 male, age 59.2 ± 11.1) underwent pre-procedural magnetic resonance imaging the heart torso followed by cardiac using NEEES. Data processing consisted merging radiographic obtained In all an...
Purpose: The aim of the present study was to estimate accuracy a novel noninvasive epicardial and endocardial electrophysiology system (NEEES) for mapping ventricular ectopic arrhythmias. Method: This enrolled 20 patients with monomorphic premature contractions (PVC) or tachycardia (VT). All underwent preprocedural computed tomography (CT) magnetic resonance imaging (MRI) heart torso. Up 224 body-surface electrodes were connected NEEES (EP Solutions SA, Switzerland) followed by unipolar ECG...
Purpose: This study assessed phase mapping approach for noninvasive of atrial flutter (AFl) applying a novel epicardial and endocardial electrophysiology system (NEEES) as compared to invasive elepctroanatomical mapping. Method: Patients with persistent AFl underwent cardiac computed tomography or magnetic resonance imaging followed by NEEES (EP Solutions SA, Switzerland) analysis. The noninvasively reconstructed unipolar electrograms (EG) was electroanatomical data obtained the CARTO 3...
Introduction: This study investigated radiofrequency ablation (RFA) of focal atrial tachycardia (AT) originating from the His bundle region. Methods: included 32 patients (22 females, age 58 ± 12 years) with AT localising near bundle. Activation mapping right atrium (RA; n = 32), left (LA; 16) and non-coronary cusp (NCC; 26) was performed during to identify earliest activation site. The site successful RFA served as final confirmation origin. Conclusion: region should be carefully mapped in...
Purpose: Understanding of the basic mechanisms atrial fibrillation (AF) maintenance and termination may help to optimise AF treatment. The objective this study was analyse process in humans.
Background: The detection of rotors in patients with atrial fibrillation (AF) using invasive and noninvasive mapping systems was described multiple studies. However, there is a lack information about the stability over time. Methods: A total 4 (2 male, age 60 ± 12 years, left (LA) diameter 47 8) persistent AF underwent gadolinium enhanced MRI torso, followed by repetitive ECG recordings 3-hours intervals novel body-surface system (EP Solutions, Yverdon-les-Bains, CH). Therefore, up to 224...
Purpose: The aim of this study was to determine the long-term outcomes (all-cause mortality, sudden cardiac death (SCD), and incidence appropriate inappropriate implantable cardioverter defibrillator (ICD) therapy) after extensive left ventricular septal myectomy in patients with diffuse-generalized form obstructive hypertrophic cardiomyopathy (HOCM). Method: This included 54 consecutive HOCM treated either (group A) or medical therapy B). Group A consisted 22 (50.1±11.8 y.o., 11 females, 1...