A5101414797- Obstructive Sleep Apnea Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- High Altitude and Hypoxia
- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Cancer-related molecular mechanisms research
- Atomic and Subatomic Physics Research
- Vascular Tumors and Angiosarcomas
- Radiation Therapy and Dosimetry
- Alzheimer's disease research and treatments
- Viral Infections and Vectors
- Cardiac tumors and thrombi
- Estrogen and related hormone effects
- Phytoestrogen effects and research
- Air Quality Monitoring and Forecasting
- Diverse Approaches in Healthcare and Education Studies
- Redox biology and oxidative stress
- Inflammation biomarkers and pathways
- Pleural and Pulmonary Diseases
- Acute Myocardial Infarction Research
- Ferroptosis and cancer prognosis
- Sarcoma Diagnosis and Treatment
Tianjin Medical University General Hospital
2012-2024
Chinese People's Liberation Army
2024
Taiyuan Central Hospital
2022
Inner Mongolia University for Nationalities
2021
Tianjin Medical University
2009-2019
Creative Commons
2019
Nanjing Medical University
2019
Abstract Background Patients with sepsis low albumin levels and high red blood cell distribution width have poor prognoses. Red to ratio (RAR) has recently attracted attention as an innovative inflammation biomarker. We aimed explore the association between RAR prognosis of patients sepsis. Methods This retrospective observational study included 402 meeting sepsis-3 standards admitted Yantai Yuhuangding Hospital’s intensive care units (ICUs) January 2020 December 2022. The relationship...
Bloodstream infections are globally occurring life-threatening diseases that impose significant societal and economic burdens. This study explored the red cell distribution width (RDW) to albumin ratio (RAR), a novel index derived from RDW, investigate its relationship with prognosis of bacteremia using propensity score matching (PSM). retrospective observational cohort included patients admitted Yantai Yuhuangding Hospital's intensive care units June 2019 December 2022. PSM was performed...
Abstract Background The associations between short- and long-term exposure to ambient fine particulate matter with an aerodynamic diameter ≤ 2.5 µm (PM ) allergic symptoms in middle-aged elderly populations remain unclear, particularly China, where most cities have severe air pollution. Methods Participants (n = 10,142; age 40–75 years) were recruited from ten regions China 2018 2021 for the Predictive Value of Inflammatory Biomarkers Forced Expiratory Volume 1 s (FEV Chronic Obstructive...
The coexistence of chronic obstructive pulmonary disease (COPD) and sleep apnea (OSA) is termed overlap syndrome (OS). COPD OSA both have increased risks developing cardiovascular diseases. This study aimed to explore if patients with OS exhibited a higher prevalence complications, vascular endothelial dysfunction abnormalities in the cellular immune function T lymphocytes.Totally 25 stable (COPD group), (OSA (OS 20 healthy adults (control group) were enrolled between January 2017 December...
Purpose: COPD-OSA (chronic obstructive pulmonary disease–obstructive sleep apnea) overlap syndrome is associated with more frequent COPD acute exacerbations than without OSA. With the application of high-resolution computed tomography (HRCT) in COPD, bronchiectasis commonly detected and disease severity. Sleep respiratory also bronchiectasis; however, correlation between OSA coexisted (COPD-Bx) has not been reported yet. Patients Methods: A total 124 consecutive patients stable were...
Abstract Background Clinical characteristics of patients with pulmonary thromboembolism have been described in previous studies. Although very old are a special group based on comorbidities and age, they do not receive attention. Objective This study aims to explore the clinical mortality predictors among relatively large population. Design participants The included total 7438 from national, multicenter, registry study, China pUlmonary REgistry Study (CURES). Consecutive acute were enrolled...
Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular (CVD), their coexistence is known as overlap syndrome (OS). Endothelial dysfunction the initial stage CVD; however, underlying mechanisms linking OS CVD not well understood. The aim this study was to explore whether can lead more severe inflammation endothelial apoptosis by promoting dysfunction, assess intervention effects antioxidant tempol. Male Wistar rats (n=66) were exposed...
The present research was to assess the relationship between ABCB1 (G2677T/A, C3435T) polymorphisms and lipid homeostasis as well risk of liver injury induced by atorvastatin in in-patients from China. levels (total cholesterol, high-density lipoprotein, triglycerides) metabolic enzymes hepar (glutamic-pyruvic transaminase, glutamic-oxalacetic alkaline phosphatase, γ-glutamyl transpeptidase) plasma for 162 patients were measured at baseline after approximately 6 months treatment....
Objective To explore the measurement of (1, 3)-β-D -glucan bronchoalveolar lavage fluid (BALF) for diagnosis pulmonary fungal infections. Methods A total 135 patients in General Hospital Tianjin Medical University from February 2010 to 2011 were enrolled. There 34 cases confirmed or clinically diagnosed infections, 53 bacterial pneumonia, and 48 non-infection diseases. All underwent BAL BALF samples obtained. 3)-β-D-glucan content (G test), plasma tested data analyzed statistically by...
Background:Menopausal hormone therapy (MHT) has been receiving increasing attention in developed countries.The purpose of this study was to investigate understanding menopause and acceptance MHT Qinhuangdao, China. Material/Methods:We analyzed data from 186 perimenopausal patients on topics including menopausal symptoms adherence treatment.We also surveyed 100 medical staff menopausal-related knowledge. Results:Group A consisted 41 treated with for more than 1 cycle, group B 49 who had...
Background & Objectives: Sepsis is a leading cause of mortality and critical illness[1]. ALI/ARDS remain common complications sepsis, which intimately connected with the structure function mitochondrion[2]. Hydrogen gas (H2) exerts significant role in treatment sepsis[3]. Objective to evaluate effects H2 on mitochondrial morphology sepsis-induced acute lung injury mice Materials Methods: 104 male ICR mice, weighing 20-25g aged 6 weeks, were randomly divided into 4 groups (n=26 each): sham...
Evidence demonstrates that the immune microenvironment is extensively associated with chemotherapy response of ovarian cancer (OV). Herein, this study aimed at establishing a cisplatin prediction model for OV on basis genes.The expression profiles cisplatin-sensitive and cisplatin-resistant specimens were integrated from multiple public datasets. The abundance scores 22 cells estimated CIBERSORT algorithm. Differentially expressed genes (DEGs) determined between groups. Thereafter, was...
Objective To study effects of metformin on the cultured eutopic endometrial cells from patients with endometriosis (EMS). Methods From January to July 2012, a total 50 samples EMS were included into group. At same time, another 88 form cases who underwent operation because cervical lesions, uterine septum, ovarian teratoma, cyst control There no significant differences general information (eg. age) between two groups (P>0.05). The cell model was established. incubated without or...
Objective To improve the understanding of pulmonary embolism with normal D-dimer level through analysis 22 cases.Methods cases patients in Tianjin Medical University General Hospital admitted from January 2004 to April 2011 were retrospectively analyzed.These had and confirmed as by chest CT or ventilation perfusion lung scan.Results The basic diseases included hypertension,coronary heart disease,previous history deep venous thrombosis embolism.Wells score:low clinical probability (＜2...
There are no uniform diagnostic criteria for right ventricular dysfunction in patients with acute pulmonary embolism,domestic and international guidelines always make comprehensive evaluation by a variety of inspection methods.Whether thrombolytic therapy is better than anti-coagulation sub-massive embolism patients,there has been considerable controversy.The article summarizes information about diagnosis treatment embolism. Key words: Pulmonary embolism; Right ; Diagnosis; Treatment
Objective To compare therapeutic efficacy of thrombolysis and anticoagulation in acute pulmonary embolism,and to analyze the trend rate. Methods The clinical data 190patients with embolism our hospital were retrospectively analyzed. They divided into group group. rate, effective bleeding rate recurrence compared between two groups. Results rates on three stages 2001-2003 (A), 2004-2006(B), 2007-2009(C)were 45.7%, 31.3 %, 15.3 which gradually decreased.There was statistical significance A,B C...