- Venous Thromboembolism Diagnosis and Management
- Hydrocarbon exploration and reservoir analysis
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related molecular mechanisms research
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Geological and Geophysical Studies
- Nutrition and Health in Aging
- Methane Hydrates and Related Phenomena
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Hydraulic Fracturing and Reservoir Analysis
- Pleural and Pulmonary Diseases
- CO2 Sequestration and Geologic Interactions
- Asthma and respiratory diseases
- Central Venous Catheters and Hemodialysis
- Nosocomial Infections in ICU
- Acute Ischemic Stroke Management
- Clinical Nutrition and Gastroenterology
- Intensive Care Unit Cognitive Disorders
- Diagnosis and Treatment of Venous Diseases
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Geological and Geochemical Analysis
Sichuan University
2014-2025
West China Hospital of Sichuan University
2012-2025
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
China University of Petroleum, Beijing
2021-2024
Chinese PLA General Hospital
2019-2024
University of Petroleum
2021
First Affiliated Hospital of GuangXi Medical University
2020
Guangxi Medical University
2020
Sichuan Cancer Hospital
2014
The optimal risk assessment model (RAM) to stratify the of venous thromboembolism (VTE) in medical inpatients is not known. We examined and compared how well Padua Prediction Score (PPS) Caprini RAM VTE inpatients.We undertook a retrospective case-control study among admitted large general hospital China during 4-year period. In total, 902 cases were confirmed have hospitalization controls selected randomly match by service.The increased significantly with an increase cumulative PPS or...
Subjects with chronic respiratory symptoms and preserved pulmonary function (PPF) may have small airway dysfunction (SAD). As the most common means to detect SAD, spirometry needs good cooperation its reliability is controversial. Impulse oscillometry (IOS) complete deficiency of higher sensitivity. We aimed explore diagnostic value IOS SAD in symptomatic subjects PPF.The evaluation symptoms, results 209 PPF were assessed. ROC curves analyzed.209 included. who reported sputum had R5-R20 Fres...
Astragaloside IV (AS-IV) is an inartificial saponin separated from astragalus membranaceus, which has exhibited key anti-tumor regulation in some cancers. Circular RNAs (circRNAs) are important regulators malignant development of gastric cancer (GC). Herein, we focused on the molecular mechanism AS-IV with circRNA dihydrolipoamide S-succinyltransferase (circDLST) GC. CircDLST, microRNA-489-3p (miR-489-3p), and eukaryotic translation initiation factor 4A1 (EIF4A1) levels were detected by...
We previously showed that microRNAs (miRNAs) in plasma are potential biomarkers for cigarette smoking-related lung fibrosis. Here, we want to find out promising miRNAs early detection of chronic obstructive pulmonary disease (COPD).Plasma profiling was performed COPD patients, asthma and matched healthy controls. There a >2-fold changes all signature between the control samples, with P values < 0.05. Pathway analysis, taking into account enriched target mRNAs these miRNAs, also carried out....
The appropriate selection of hospitalized patients for venous thromboembolism(VTE) prophylaxis is an important unresolved issue. We sought to validate the Caprini model, a famous individual VTE risk assessment model(RAM), in Chinese patients.We performed retrospective case-control study among unselected admitted comprehensive hospital China. A total 347 were confirmed have during hospitalization, and 651 controls randomly selected match according medical service. Both retrospectively...
Pleural effusion is observed in a subset of patients with acute pulmonary embolism (APE) and may be linked to clinical outcome, but findings from previous studies have been inconsistent. This study aimed investigate the prevalence significance pleural Chinese APE.Clinical data hospitalized APE were retrospectively collected was determined. The relationship between presence outcome analyzed by Cox proportional hazards regression Kaplan-Meier survival analysis.The enrolled 635 APE. 57.01%...
<h3>ABSTRACT</h3> <h3>Background</h3> Fat embolism syndrome (FES) is a rare life-threatening complication, which commonly affects the lung. Currently, most widely accepted criteria for diagnosis of FES are Gurd and Wilson Criteria established nearly 40 years ago, but without pulmonary images involved. Our study aims to analyse computed tomography (CT) findings seen in FES. <h3>Case presentation</h3> This report enrolled four cases with lung involvement. The mainly symptoms signs included...
Abstract Background Most resting energy expenditure (REE) predictive equations for adults were derived from research conducted in western populations; whether they can also be used Chinese young people is still unclear. Therefore, we this study to determine the best REE equation normal weight adults. Methods Forty-three (21 male, 22 female) healthy college students between age of 18 and 25 years recruited. was measured by indirect calorimetry (IC) method. Harris-Benedict, World Health...
Abstract Backgroud: Severe pneumonia is one of the most common causes for mechanical ventilation. We aimed to early identify severe patients with high risk extubation failure in order improve prognosis. Methods: From April 2014 December 2015, medical records intubated intensive care unit were retrieved from database. Patients divided into success and groups, multivariate logistic regressions performed independent predictors failure. Results: A total 125 eligible included, which 82 43 had...
Nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasomes are the most important factors in ventricular arrhythmia associated with heart failure (VA-HF). However, how relationship between lncRNA and NLRP3 is regulated VA-HF has not been investigated detail. Thus, we aimed to determine effects of SOX2-overlapping transcripts (SOX2-OT) by targeting rats VA-HF.We established (SPF, male, weight: 240 ± 10 g) aortic coarctation constant-current...
Assist/control (A/C) ventilation may induce delirium in patients with acute respiratory distress syndrome (ARDS). We conducted a trial to determine whether initial synchronized intermittent mandatory pressure support (SIMV + PS) could improve clinical outcomes these patients.Intubated moderate ARDS were enrolled and we compared SIMV PS A/C. Identical sedation, analgesia strategies performed. The co-primary early (≤72 h) partial of arterial oxygen fraction inspired (PaO2/FiO2) incidence...
Abstract Background Inpatients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are at increased risk for venous thromboembolism (VTE); however, the prophylaxis VTE is largely underused in China. Identifying high-risk patients requiring thromboprophylaxis critical to reduce mortality and morbidity associated VTE. This study aimed evaluate compare validities Padua Prediction Score Caprini assessment model (RAM) predicting inpatients AECOPD Methods The were...
Background: Severe pneumonia is the predominant cause for acute respiratory distress syndrome (ARDS). Identification of ARDS from patients with severe remains a significant clinical problem due to overlap presentations and symptoms. Early recognition risks great value. Methods: From April 2014 December 2015, at admission were retrieved hospital database, which developed within 7 days further identified. We compared demographic characteristics between without development, followed by analysis...
Pulmonary paragonimiasis is a food-borne zoonosis with wide variety of radiologic findings, which sometimes can be confused tuberculosis and carcinoma. Therefore, differential diagnosis always warranted. A 43-year-old male farmer, productive cough, blood-tinged sputum chest pain, as well patchy consolidation pleural effusions in computer tomography, was misdiagnosed community-acquired pneumonia tuberculosis. Complete blood cell count, smear culture, thoracoscopy, biopsy. The pulmonary...
Abstract Objective This article aimed to validate and compare the prognostic performance of generic scores (Pulmonary Embolism Severity Index [PESI] Hestia) cancer-specific pulmonary embolism (PE)/venous thromboembolism (VTE) scales (Registro Informatizado de la Enfermedad TromboEmbólica [RIETE], POMPE-C, modified Ottawa) in PE patients with active cancer. Methods A retrospective study was conducted among 460 The primary outcome 30-day overall mortality. Secondary outcomes were PE-related...
This study aimed to evaluate the optimal risk assessment model (RAM) stratify of venous thromboembolism (VTE) in hospitalized patients with cancer. We examined and compared VTE predictive ability Khorana score (KS) Caprini RAM cancer patients.We performed a retrospective case-control among admitted comprehensive hospital China from January 2015 December 2016. A total 221 cases were confirmed have during hospitalization controls selected randomly. The KS implemented individual scores each...
Deep fluid activity is widespread in large oil-gas basins around the world. fluids, as links between internal and external factors of a basin, run way organic-inorganic interactions through formation aggregation. Herein, identification characteristics deep fluids sedimentary well their influence on reservoir geothermal resource are summarized. The identified from three aspects, including mineral composition, inclusions, geochemical characteristics. effects activities manifested two key...