A5065280099- Salivary Gland Tumors Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- Autoimmune and Inflammatory Disorders
- Tumors and Oncological Cases
- Autoimmune Bullous Skin Diseases
- Cutaneous Melanoma Detection and Management
- Ear and Head Tumors
- Cell Adhesion Molecules Research
- Systemic Lupus Erythematosus Research
- Cancer-related molecular mechanisms research
- Bone Tumor Diagnosis and Treatments
- Oral and gingival health research
- Sarcoma Diagnosis and Treatment
- Cancer and Skin Lesions
- Infectious Diseases and Mycology
- Cancer Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Nonmelanoma Skin Cancer Studies
- Barrier Structure and Function Studies
- Head and Neck Cancer Studies
- Skin and Cellular Biology Research
- Cutaneous lymphoproliferative disorders research
- Oral microbiology and periodontitis research
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2004-2025
Universidade de São Paulo
2016-2025
Fundação Faculdade de Odontologia
2001-2025
AC Camargo Hospital
2008-2022
Universidade Brasil
2011-2022
Instituto de Medicina Avançada
2003-2022
Institut de Virologie
2021
Hospital do Espírito Santo
2020
Instituto de Patologia da Coluna
2018
University of Hong Kong
2018
We associated clinical-pathological features of 142 OSCC with the expression pattern GLUT1 and GLUT3 in order to estimate their prognostic value. Methods: Clinical-pathological overall survival data patients Oral Squamous Cell Carcinoma (OSCC) were retrospectively reviewed from A.C.Camargo hospital records. A tissue microarray (TMA) was built for immunohistochemical (IHC) analysis GLUT 1 3. IHC results evaluated according staining number positive cells. Results: over expressed 50.3% OSSC...
Background: Lupus erythematosus (LE) is a multifactorial autoimmune disease, which may affect the oral mucosa in either its cutaneous and systemic forms, with varied prevalence. Methods: Forty‐six patients confirmed diagnosis of LE, presenting lesions were included study. Oral mucosal analyzed clinically, their histopathological features investigated inflammatory infiltrate constitution was assessed using immunohistochemistry against following clusters differentiation: CD3, CD4, CD8, CD20,...
Background: Actinic cheilitis (AC), is the very superficial, incipient form of actinically induced squamous cell carcinoma lower lip. Few studies actinic analyzed entire lip vermilion searching for microscopic areas progressing carcinoma. Methods: Twenty patients with biopsy proved presenting diffuse clinical changes were submitted to vermilionectomy Surgical specimens sectioned every 3 mm, studied histopathologically and findings compared biopsy. Histological classified as ‘AC’, in situ...
In assessing the impact of climate change on infrastructure, it is essential to consider interactions between atmosphere, vegetation and near-surface soil. This paper presents an overview these processes, focusing recent advances from literature those made by members COST Action TU1202 – Impacts engineered slopes for infrastructure. Climate- vegetation-driven processes (suction generation, erosion, desiccation cracking, freeze–thaw effects) are expected in incidence severity, which will...
Abstract Introduction Ameloblastomas are neoplasms that have inspired great controversy and clinical interest; their incidence, radiographic features, treatment behavior still discussed quite often in the literature. In 2017, classification of these lesions underwent modifications terminology with introduction prospective views based on updates current genetic studies. Objective To describe most important features new classification, as well to evaluate prevalence characteristics 136...
Oral mucosal melanoma is rare and reported to be more aggressive than its cutaneous counterpart. Due the rarity of this entity, data on epidemiology, tumor behavior, treatment, follow-up, survival patients are mainly based single case reports. The few existing series show that oral mucosa has peak between 41 60 years age, male female ratio 2:1. Preferred sites include hard palate maxillary alveolar crests. Risk factors have not been clearly identified, surgical treatment still choice for...
ABSTRACT Objectives Primary Sjögren's disease (SjD) is a slow‐progressing autoimmune that affects salivary and lacrimal glands, causing dry eyes (xerophthalmia) mouth (xerostomia). Diagnosing SjD involves clinical, serological, histological assessments, but reliable biomarkers are lacking. Methods This study analyzed the metabolic proteomic profiles of 19 female patients (based on ACR‐EULAR criteria) compared to 20 healthy individuals. Saliva blood samples were using mass spectrometry...
Abstract: Mucoceles are common benign lesions of the oral cavity that develop following extravasation or retention mucous material from major minor salivary glands. Most series report a higher incidence mucocele in young patients but no studies exist for this specific age group. The records 104 presenting with who underwent surgery Oral Diseases Clinic Department Dermatology University São Paulo, Brazil, between 1991 and 2006, were reviewed. Of these, 36 (34.6%) 15 years old younger,...
Fgf10 is necessary for the development of a number organs that fail to develop or are reduced in size null mutant. Here we have knocked out specifically neural crest driven by Wnt1cre. The Wnt1creFgf10fl/fl mouse phenocopies many mutant defects, including cleft palate, loss salivary glands, and ocular highlighting origin expressing mesenchyme surrounding these organs. In contrast tissues such as limbs lungs, where expressed mesoderm, were unaffected, was pituitary gland neuroepithelium....
Myoepithelial cells are important components of salivary gland structure, aiding the expulsion saliva from acinar lobules. The aim was to evaluate expression smooth muscle actin (SMA), calponin, caldesmon, CD10, CD29, S100 protein, glial fibrillary acidic protein (GFAP) and p63 in myoepithelial during morphogenesis understand maturation process these their possible use diagnosis lesions.Major minor human glands at various stages development, derived fetuses 8-26 weeks gestation, were studied...
Coutinho‐Camillo C M, Lourenço S V, Nishimoto I N, Kowalski L P & Soares F A (2010) Histopathology 57 , 304–316 Expression of Bcl‐2 family proteins and association with clinicopathological characteristics oral squamous cell carcinoma Aims: To characterize the expression that inhibit (Bcl‐2, Bcl‐x, Bcl‐xL, Bcl‐2‐related protein A1, BAG‐1) or promote (Bak, Bax, Bim/Bod, Bim‐Long, Bad, Bid, PUMA) apoptosis determine possible correlations between these features (OSCC). Methods results:...
Abstract Background Apoptosis is a genetically programmed form of cell death, which caspases are the central components. Methods By tissue microarray 229 cases oral squamous carcinoma (OSCC), we analyzed immunoexpression 3, 6, 7, 8, 9, and 10. Results All proteins that examined were expressed in primary OSCC samples. Caspases 8 9 prominently expressed, 10 occasionally expressed. Disease‐free survival differed significantly between caspase 7 high‐expressing low‐expressing patients, our...
Aims Claudins are integral transmembrane proteins of the tight junctions, critical for maintaining cell adhesion and polarity. Alterations in expression individual claudins have been detected carcinomas appear to correlate with tumour progression. Methods In this study, a panel anti-claudin antibodies (anti-claudins 1, 2, 3, 4, 5 7) was employed map claudin 136 cases oral squamous carcinoma (OSCC) organised tissue microarray. Results were expressed reticular pattern up prickle layer normal...
J Oral Pathol Med (2012) 41 : 584–588 Pyostomatitis vegetans (PSV) is an intraoral pustular eruption considered by most authors to represent the mucous analogous of cutaneous pyoderma gangrenosum and its vegetating presentations (pyodermatitis vegetans). A strong correlation PSV with inflammatory bowel disease (IBD) well documented. The histopathology lesions usually reveals acanthosis, neutrophils and/or eosinophils infiltration intraepithelial or subepithelial abscesses; acantholysis...
Summary Introduction Actinic cheilitis ( AC ) is a lip intraepithelial neoplasia, whose cells present alterations similar to those presented by invasive squamous cell carcinomas SCC s). Objective To conduct clinical and laboratory evaluation histopathology immunohistochemistry of the efficacy actinic treatment using photodynamic therapy PDT with methyl aminolevulinate MAL noncoherent red light. Materials methods Patients detected histopathological examination were submitted two sessions...