A5076803884- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Petroleum Processing and Analysis
- Hydrocarbon exploration and reservoir analysis
- Analytical chemistry methods development
- Enhanced Oil Recovery Techniques
- Advanced Proteomics Techniques and Applications
- Cultural Heritage Materials Analysis
- Cholinesterase and Neurodegenerative Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mindfulness and Compassion Interventions
- Computational Drug Discovery Methods
- Isotope Analysis in Ecology
- Atmospheric chemistry and aerosols
- Textile materials and evaluations
- Forensic and Genetic Research
- Antibiotics Pharmacokinetics and Efficacy
- Protein Hydrolysis and Bioactive Peptides
- Metabolomics and Mass Spectrometry Studies
- Spectroscopy and Chemometric Analyses
- Chalcogenide Semiconductor Thin Films
- Pneumonia and Respiratory Infections
- Protein purification and stability
- Thermodynamic properties of mixtures
- Religion, Spirituality, and Psychology
Merck & Co., Inc., Rahway, NJ, USA (United States)
2022-2025
Purdue University West Lafayette
2016-2023
University of Wisconsin–Madison
2022
State University of New York
2016
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRecent Advances in Petroleum Analysis by Mass SpectrometryEdouard NiyonsabaEdouard NiyonsabaDepartment of Chemistry, Purdue University, West Lafayette, Indiana 47907, United StatesMore Edouard NiyonsabaView Biography, Jeremy M. ManheimJeremy ManheimDepartment ManheimView Ravikiran YeraboluRavikiran YeraboluDepartment YeraboluView and Hilkka I. Kenttämaa*Hilkka KenttämaaDepartment States*Phone: +1 (765) 494 0882. Fax: 9421. E-mail: [email...
Hair and fibers are common forms of trace evidence found at crime scenes. The current methodology microscopic examination potential hair is absent statistical measures performance, examiner results for identification can be subjective. Here, attenuated total reflection (ATR) Fourier transform-infrared (FT-IR) spectroscopy was used to analyze synthetic natural hairs human, cat, dog origin. Chemometric analysis differentiate spectra from the three different species, predict unknown their...
Direct infusion atmospheric pressure chemical ionization mass spectrometry (APCI-MS) was compared to field (FI-MS) for the determination of hydrocarbon class distributions in lubricant base oils. When positive ion mode APCI with oxygen as source gas employed ionize saturated model compounds (M) hexane, only stable [M - H]+ ions were produced. Ion-molecule reaction studies performed a linear quadrupole trap suggested that fragment ionized hexane can hydrocarbons via hydride abstraction...
There is currently a lack of harmonization from health agencies on the control strategies that should be implemented for manufacture synthetic peptide active pharmaceutical ingredients throughout clinical development and commercialization. In this Perspective, we use term "peptide" to refer an α-amino acid polymer with specific defined sequence without regard total number amino acids it contains. U.S., FDA defines "proteins" are subject biological product licensure as follows: "A protein any...
Chemical characterization of complex mixtures large saturated hydrocarbons is critically important for numerous fields, including petroleomics and renewable transportation fuels, but difficult to achieve. Atmospheric pressure chemical ionization (APCI) mass spectrometry has shown some promise in the analysis hydrocarbons. However, APCI causes extensive fragmentation these compounds, which impedes its effectiveness. To prevent this fragmentation, were examined via gas-phase ion–molecule...
Since its invention in the 1950s, field ionization mass spectrometry (FI MS) has been, and currently is, go-to technique employed by petrochemical industry for identification of different types nonvolatile compounds their products. Unfortunately, FI MS several inherent drawbacks, such as poor reproducibility. The performance positive-ion mode atmospheric pressure chemical (APCI with O2 gas sheath/auxiliary a saturated hydrocarbon solvent/reagent was recently compared that found to show...
The amine–thiol solvent system has been used extensively to synthesize metal chalcogenide thin films and nanoparticles because of its ability dissolve various chalcogen precursors. While previous studies this have focused on understanding the dissolution precursors, here we provide an in-depth investigation chalcogens, specifically Se Te. Analytical techniques, including Raman, X-ray absorption, NMR spectroscopy high-resolution tandem mass spectrometry, were identify pathways for Te in...
Linear alkanes are a class of compounds known to negatively affect the physical performance lubricant base oils. The ability rapidly identify and quantify linear in oils would enable oil companies more effectively evaluate their refinery methods for converting crude While mass spectrometry is powerful method elucidation structures complex mixtures, it not innately quantitative. An approach presented here identification quantitation samples by utilizing GC×GC/EI TOF MS. Identification was...
Abstract Biopolymer analysis, including proteomics and glycomics, relies heavily on the use of mass spectrometry for structural elucidation, sequence determination. Novel methods to improve sample workup, instrument performance, data analysis continue be developed address shortcomings associated with preparation, time, quality, interpretation. Here, we present a new method that couples in‐source collision‐induced dissociation (IS‐CID) two‐dimensional tandem (2D MS/MS) as way simplify...
Chemical characterization of complex mixtures large alkanes is critically important for many fields, including petroleomics and the development renewable transportation fuels. Tandem mass spectrometry only analytical method that can be used to characterize such at molecular level. Many ionization methods in involve proton transfer analyte. Unfortunately, very few affinity (PA) values are available alkanes. Indeed, previous research has shown most protonated (MH+) not stable but fragment...
Abstract Biopolymer analysis, including proteomics and glycomics, relies heavily on the use of mass spectrometry for structural elucidation, sequence determination. Novel methods to improve sample workup, instrument performance, data analysis continue be developed address shortcomings associated with preparation, time, quality, interpretation. Here, we present a new method that couples in‐source collision‐induced dissociation (IS‐CID) two‐dimensional tandem (2D MS/MS) as way simplify...
Chemically enhanced oil recovery (cEOR) is an expensive endeavor that yields modest levels of recovery. In order to make it economically viable, improved understanding the process needed. For example, knowledge types compounds in crude are strongly bound reservoir surfaces would facilitate design more efficient cEOR formulations. this research study, fractionation step previously published distillation, precipitation, and mass spectrometry (MS) method was utilized determine or weakly...
The performance of positive-ion mode atmospheric pressure chemical ionization linear quadrupole ion trap orbitrap mass spectrometry (APCI LQIT Orbitrap MS) has been compared to that two-dimensional gas chromatography coupled with electron time-of-flight (GCxGC/EI TOF for the analysis group III heavy base oils. Isooctane was used as solvent in APCI MS experiments. Under these conditions, all compounds were predominantly ionized via protonation. However, protonated alkanes are not stable and...