A5034372271- Nanoparticle-Based Drug Delivery
- Advanced Polymer Synthesis and Characterization
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Block Copolymer Self-Assembly
- Eosinophilic Disorders and Syndromes
- Hydrogels: synthesis, properties, applications
Queen Mary University of London
2019-2020
University of Sheffield
2016
RAFT-synthesized polymers are typically colored and malodorous due to the presence of sulfur-based RAFT end-group(s). In principle, end-groups can be removed by treating molecularly dissolved copolymer chains with excess free radical initiators, amines, or oxidants. Herein we report a convenient method for removal from aqueous dispersions diblock nano-objects using H2O2. This oxidant is relatively cheap, has minimal impact on morphology, produces benign side products that readily via...
Covalently crosslinked nanogels are widely explored as drug delivery systems and sensors. Radical polymerization provides a simple, inexpensive, broadly applicable approach for their preparation, although the random nature of reaction requires careful study final chemical composition. We demonstrate how different reactivities monomers influence total degree incorporation into polymer matrix role played by experimental parameters in maximizing efficiency. Nanogels based on...