- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Congenital Heart Disease Studies
- Nutrition and Health in Aging
- Cardiovascular Function and Risk Factors
- Transplantation: Methods and Outcomes
- Intensive Care Unit Cognitive Disorders
- Fuel Cells and Related Materials
- Aortic Disease and Treatment Approaches
- Hip and Femur Fractures
- Maternal and fetal healthcare
- Cardiovascular Issues in Pregnancy
- Electrolyte and hormonal disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sepsis Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Reconstructive Surgery and Microvascular Techniques
- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Blood donation and transfusion practices
- Cardiac Valve Diseases and Treatments
- Surgical site infection prevention
- Acute Kidney Injury Research
University of Michigan
2020-2024
Michigan Center for Translational Pathology
2024
Advocate Christ Medical Center
2014-2020
Advocate Heart Institute
2016-2020
University of Illinois Chicago
2014-2019
Illinois College
2017-2019
Christie's
2019
Bon Secours Heart & Vascular Institute
2017
Rush University Medical Center
2016-2017
Committee on Publication Ethics
2017
There is a need to better assess the cumulative effect on morbidity and mortality in patients undergoing durable left ventricular assist device (LVAD) implantation. This study evaluates patient-centered performance metric (days alive out of hospital [DAOH]) for LVAD therapy.
The prognostic nutritional index (PNI) is a simple metric that uses serum albumin and total lymphocyte count to provide basic indicator for status. It has recently garnered attention as prognosticator of outcomes in many types cancer. We investigated the utility PNI marker poor following left ventricular assist device (LVAD) implantation. Two hundred eighty-eight consecutive patients implanted with continuous-flow LVADs were included. Prognostic was calculated all (PNI = [10 × {g/dl}] +...
Background : It has been shown that malnutrition affects clinical outcomes in patients with advanced heart failure and nutrition status, as determined by the Mini Nutritional Assessment (MNA), can be used an independent predictor of mortality. The aim this study was to evaluate prognostic utility short‐form MNA (MNA‐SF) a surrogate failure. Methods Data retrospectively gathered from assessments 162 were analyzed. Results As defined MNA, cohort included 40 (24.7%) classified malnourished, 106...
Advanced heart failure is associated with a wide range of physiological derangements, including muscular deterioration, weight loss, and cardiac cachexia. These conditions, as well poor nutrition status, have been shown to affect the quality outcomes in patients who undergo left ventricular assist device (LVAD) implantation. Noting that handgrip strength has be an effective indicator functional strength, nutrition, we investigated its use tool for prediction length stay (LOS) undergoing LVAD...
The use of left ventricular assist devices (LVADs), implantable pumps used to supplement cardiac output, has become an increasingly common and effective treatment for advanced heart failure. Although modern continuous-flow LVADs improve quality life survival more than medical management failure, device malfunction remains a concern. Improved noninvasive methods assessment LVAD function are needed detect complications. An electronic stethoscope was record sounds from the HeartMate II axial...
Left ventricular assist devices (LVADs) have become an increasingly popular and effective means for treating advanced heart failure. LVAD implantation requires extensive surgery postoperative rehabilitation. The Functional Independence Measure (FIM) has been used to quantify functional gains in numerous patient populations, including those with stroke spinal cord injury. This study investigated improvements patients undergoing using the FIM score.To assess failure who underwent...
Background: The association between extreme body mass index (BMI) and outcomes in left ventricular assist device (LVAD) patients has not been well established.With the commercial use of LVADs a larger number with BMI >40 have undergone implantation.The purpose this study was to evaluate short long-term LVAD obesity.Methods: A retrospective review all (n=383) at our center who received as primary implant 2005-2015 performed.Demographics, preoperative laboratory values, postoperative were...
The neutrophil-to-lymphocyte ratio (NLR) has been used to predict mortality in a wide range of cardiovascular diseases including acute decompensated heart failure and non-ST-elevation myocardial infarction. We investigated the prognostic utility NLR patients with advanced who received left ventricular assist devices (LVADs). Two hundred seventy-three implanted LVADs at our institution were divided into tertiles based on their retrospectively analyzed. Outcomes, survival right (RV) failure,...
Hemodynamic support with continuous-flow left ventricular assist device (CF-LVAD) therapy has proven a reliable treatment for advanced heart failure. Although modern LVADs are highly durable, failure and infection can be resolved surgical exchange of pump components. In this study, we investigated the incidence outcomes LVAD HeartMate II HeartWare HVAD. Data were obtained from 677 patients who underwent CF-LVAD implantation between 2005 2016. Patients exchanged included. The primary length...
Diabetes mellitus is associated with adverse outcomes in patients cardiovascular diseases, including heart failure. Left ventricular assist devices (LVADs) are increasingly used as life-saving therapy for advanced The effects of pre-LVAD diabetes on long-term after LVAD implantation not well understood. In this study, we retrospectively evaluated the effect existing post-LVAD outcomes. Data 288 recipients from 2006 through 2013 were reviewed. Patients stratified accordance their histories...
Left ventricular assist device (LVAD) implantation for advanced heart failure is known to improve survival, functional capacity, and quality of life. Most patients implanted with LVADs suffer from moderate severe malnutrition deconditioning due their disease. The Mini Nutritional Assessment (MNA) the short form survey (MNA-SF) are 2 well-validated clinical tools, previously used assess patient nutrition status in numerous conditions. Earlier work has demonstrated that low scores can...
Left ventricular assist devices (LVADs) are increasingly being used as life-saving therapy in patients with end-stage heart failure. The changes spirometry following LVAD implantation and subsequent unloading of the left ventricle pulmonary circulation unknown. In this study, we explored long-term after placement. retrospective compared baseline preoperative function test (PFT) results to post-LVAD spirometric measurements. Our indicated that tests were significantly reduced placement...
Background: Malnutrition is known to negatively impact the clinical course of advanced heart failure and associated with increased mortality following left ventricular assist device (LVAD) implantation. Appropriate assessment nutrition requirements in these patients critical their care, yet there has been little discussion on how best determine resting energy expenditure (REE) hospital setting. We investigated use indirect calorimetry a group failure. Materials Methods : Results from...
Vitamin D is an important hormone that regulates cardiac myocyte function. Low levels contribute to the development of cardiovascular disease and have been implicated in immune function inflammatory cascade. Patients who undergo left ventricular assist device (LVAD) implantation are at risk for driveline infection, stroke, gastrointestinal (GI) bleeding. We investigated whether serum 25-hydroxy (25-OH) vitamin affect clinical outcomes after LVAD.212 patients underwent LVAD between 2010 2015...
Introduction: The neutrophil to lymphocyte ratio (NLR) has proven be a robust predictor of mortality in wide range cardiovascular diseases. This study investigated the predictive value NLR patients supported by extracorporeal membrane oxygenation (ECMO) systems. Methods: included 107 who underwent ECMO implantation for cardiogenic shock. Median preoperative was used divide cohort, with Group 1 <14.2 and 2 ≥14.2. Survival, primary outcome, compared between groups. Results: cohort composed...
Despite modifications and a procedure to externally replace the distal portion of percutaneous lead, damage wiring insulation causing an electrical short ground, referred as shield (STS), has become important factor in longevity HeartMate II left ventricular assist device (LVAD). Device exchange been suggested treatment option. The aim this study was evaluate long-term clinical outcomes patients with STS supported on ungrounded cable. A retrospective review all (n = 479) implanted at our...