Panagiotis Barmpalexis

ORCID: 0000-0002-6765-512X
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • Advancements in Transdermal Drug Delivery
  • Analytical Methods in Pharmaceuticals
  • biodegradable polymer synthesis and properties
  • Crystallization and Solubility Studies
  • Analytical Chemistry and Chromatography
  • Oral microbiology and periodontitis research
  • Salivary Gland Disorders and Functions
  • Spectroscopy and Chemometric Analyses
  • Dental Implant Techniques and Outcomes
  • Microencapsulation and Drying Processes
  • Phytochemistry and Biological Activities
  • Advanced Polymer Synthesis and Characterization
  • Protein purification and stability
  • Polymer crystallization and properties
  • Polysaccharides Composition and Applications
  • Periodontal Regeneration and Treatments
  • Phytochemicals and Antioxidant Activities
  • Nanoparticle-Based Drug Delivery
  • Essential Oils and Antimicrobial Activity
  • Bone Tissue Engineering Materials
  • Injection Molding Process and Properties
  • Proteoglycans and glycosaminoglycans research
  • Dental Radiography and Imaging

Aristotle University of Thessaloniki
2015-2025

Hanyang University
2019

FHNW University of Applied Sciences and Arts
2019

Pharmathen (Greece)
2013

The aim of the present work is to evaluate preparation sunscreen emulsions based on chitosan (CS) nanoparticles with annatto, ultrafiltrated (UF) saffron, and saffron. Ionic gelation was used for nanoparticles, while their morphological characteristics physicochemical properties were evaluated via Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), dynamic light scattering (DLS). Results showed that prepared ranged from ~150...

10.3390/molecules23092107 article EN cc-by Molecules 2018-08-22

The application of mesoporous carriers in formulations amorphous solid dispersions (ASDs) has been suggested to enhance the stability drugs. However, do not demonstrate satisfactory inhibitory effects on precipitation active pharmaceutical ingredients (APIs), and inclusion an appropriate polymer within ASDs becomes imperative maintaining drug supersaturation. aim this study was evaluate ternary olanzapine (OLN) with Syloid 244FP find polymeric carrier. polymer's selection criteria were based...

10.3390/polym16060802 article EN Polymers 2024-03-13

The present study evaluates the preparation of risperidone controlled release microspheres as appropriate long-acting injectable formulations based on a series novel biodegradable and biocompatible poly(lactic acid)⁻poly(propylene adipate) (PLA/PPAd) polymer blends. Initially, PPAd was synthesized using two-stage melt polycondensation method (esterification polycondensation) characterized by 1H-NMR, differential scanning calorimetry (DSC), powder X-ray diffraction (XRD) analyses. DSC XRD...

10.3390/pharmaceutics10030130 article EN cc-by Pharmaceutics 2018-08-13

The treatment of osseous defects around teeth is a fundamental concern within the field periodontology. Over years, method grafting has been employed to treat bone defects, underscoring necessity for custom-designed scaffolds that precisely match anatomical intricacies cavity be filled, preventing formation gaps could allow regeneration soft tissues. In order create such patient-specific scaffold (bone graft), it imperative have highly detailed 3D representation defect, so resulting aligns...

10.3390/jpm14020207 article EN Journal of Personalized Medicine 2024-02-14

The present study evaluates the crystal growth rate of amorphous drugs when dispersed in different ternary polymeric solid dispersions (ASDs) presence surfactants. Specifically, ASDs aprepitant (APT, selected as a model drug) were prepared via melt-quench cooling by evaluating three commonly used matrix/carriers, namely hydroxypropyl cellulose (HPC), poly(vinylpyrrolidone) (PVP) and copolymer Soluplus® (SOL), two suitable surfactants, d-alpha tocopheryl polyethylene glycol 1000 succinate...

10.1016/j.ijpx.2021.100086 article EN cc-by-nc-nd International Journal of Pharmaceutics X 2021-06-05

We prepared and studied a series of triblock copolymers based on poly(ethylene glycol) (PEG) poly(lactic acid) (PLA). PLA blocks were in situ by ring-opening polymerization (ROP) lactide (LA) onto the two sites PEG. While our recent work similar with varying LA/PEG molar ratios fixed PEG [Bikiaris, N. D. Mater. Today Commun. 2024, 38, 107799], herein, we kept this ratio quite low, at 640/1, employed different molecular weights, Mn, initial 1, 4, 6, 8 kg/mol. The triblocks demonstrated high...

10.1021/acs.jpcb.5c00171 article EN cc-by The Journal of Physical Chemistry B 2025-03-19
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