A5089868494- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Digital Imaging in Medicine
- Digital Radiography and Breast Imaging
- MRI in cancer diagnosis
- Dental Radiography and Imaging
- Image Enhancement Techniques
University of Colorado Denver
2022-2025
University of Colorado Anschutz Medical Campus
2022
Background and purposeRobust scatter mitigation by 2D anti-scatter grids (2D-ASG) in proton therapy cone beam computed tomography (CBCT) may improve target visualization (CT) number fidelity, allowing online dose verifications plan adaptations. However, grid artifact-free implementation of 2D-ASG depends on the CBCT system characteristics. Thus, we investigated feasibility a gantry-mounted evaluated its impact image quality.Materials methodsA prototype support platform were developed for...
X-ray scattering adversely affects cone-beam computed tomography (CBCT) image quality, generating artifacts, causing inaccurate tissue density representation, and reducing contrast. This study evaluated the performance of a 2-dimensional antiscatter grid (2D grid) prototype in dental CBCT system. A focused 2D was fabricated from tungsten integrated with detector Residual scatter transmitted through corrected using measurement-based correction method. Phantom imaging experiments were...
Quantitative accuracy is critical for expanding the role of cone beam CT (CBCT) imaging from target localization to quantitative treatment monitoring and plan adaptations in radiation therapy. Despite advances CBCT image quality improvement methods, gap between multi-detector (MDCT) remains.
The concept of using kilovoltage (kV) and megavoltage (MV) beams concurrently has potential applications in cone beam computed tomography (CBCT) guided radiation therapy, such as single breath hold scans, metal artifact reduction, simultaneous imaging during MV treatment delivery. However, cross-scatter generated delivery degrades CBCT image quality. To address this, a 2D antiscatter grid cross scatter correction method were investigated. 3D printed, tungsten prototype was utilized to reduce...
Cone beam computed tomography (CBCT) has potential advantages for developing portable, cost-effective point-of-care CT systems intracranial imaging, such as early stroke diagnosis, hemorrhage detection, and intraoperative navigation. However, large volume imaging with flat panel detector based CBCT significantly increases the scattered radiation fluence which reduces its image quality utility. To address these issues, a compact concept enhanced was investigated imaging. The new system...
Simultaneous use of kilovoltage (kV) and megavoltage (MV) beams has numerous potential applications in cone beam computed tomography (CBCT)-guided radiotherapy, such as fast MV+kV CBCT for single breath-hold scan, tumor localization with kV imaging during MV therapy delivery, metal artifact suppression. However, the introduction results a large MV-cross scatter fluence incident on Flat Panel Detector (FPD), thus, deteriorating low contrast visualization Hounsfield Unit (HU) accuracy. In this...
Abstract Background Online dose calculations before the delivery of radiation treatments have applications in verification, online adaptation treatment plans, and simulation‐free planning. While by directly utilizing CBCT images are desired, dosimetric accuracy can be compromised due to relatively lower HU images. Purpose In this work, we propose a novel imaging pipeline enhance CBCT‐based pelvis region. Our approach aims improve images, thereby improving overall prior delivery. Methods An...
Energy sensitive and photon counting detectors can provide improved tissue visualization material quantification capabilities in Cone Beam Computed Tomography (CBCT) systems. However, their implementation CBCT systems is more challenging, which part due to high fluence of scattered X-rays wide cone angle geometry. Specifically, scatter contamination lower energy spectrum challenges reconstruction fidelity images by using X-rays. To address this problem, we investigated a robust rejection...
. Two-dimensional antiscatter grids' (2D-ASGs) septal shadows and their impact on primary transmission play a critical role in cone-beam computed tomography (CBCT) image noise artifact characteristics. Therefore, numerical simulation platform was developed to evaluate the effect of 2D-ASG's quality, as function grid geometry CBCT system properties.
Poor tissue visualization and quantitative accuracy in CBCT is a major barrier expanding the role of imaging from target localization to treatment monitoring plan adaptations radiation therapy sessions. To further improve image quality CBCT, 2D antiscatter grid based scatter rejection was combined with raw data processing pipeline iterative reconstruction. The culmination these steps referred as qCBCT. qCBCT include implementation, measurement residual scatter, lag, beam hardening correction...
Online dose calculations before radiation treatment have applications in delivery verification, plan adaptation, and planning. We propose a novel CBCT imaging pipeline to enhance accuracy. Our approach aims improve HU accuracy images for more precise calculations. A quantitative was implemented, combining data correction strategies scatter rejection, achieving high CT number evaluated the pipeline's effect using pelvis anatomy phantoms found that dosimetric errors CBCT-based were minimal. In...