Hafiza A. Sharaf

ORCID: 0000-0002-6803-1802
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About
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Research Areas
  • Drug-Induced Hepatotoxicity and Protection
  • Nigella sativa pharmacological applications
  • Curcumin's Biomedical Applications
  • Fatty Acid Research and Health
  • Chemotherapy-induced organ toxicity mitigation
  • Pharmacological Effects of Medicinal Plants
  • Heavy Metal Exposure and Toxicity
  • Seed and Plant Biochemistry
  • Lipid metabolism and biosynthesis
  • Circadian rhythm and melatonin
  • Aldose Reductase and Taurine
  • Carcinogens and Genotoxicity Assessment
  • Antioxidant Activity and Oxidative Stress
  • Moringa oleifera research and applications
  • Genomics, phytochemicals, and oxidative stress
  • Cannabis and Cannabinoid Research
  • Essential Oils and Antimicrobial Activity
  • Natural Antidiabetic Agents Studies
  • Selenium in Biological Systems
  • Genetically Modified Organisms Research
  • Hops Chemistry and Applications
  • Nanoparticles: synthesis and applications
  • Ginseng Biological Effects and Applications
  • Aluminum toxicity and tolerance in plants and animals
  • Macrophage Migration Inhibitory Factor

National Research Centre
2015-2025

National Water Research Center
2006-2010

Abstract Background The second most common cancer in the world is breast cancer. Chemotherapy used to treat cancer, but instances of multidrug resistance, targets that are not selective, and physicochemical issues raise doubts about its efficacy. So, exploration chemopreventive agents from efficient natural sources has been required. chia quinoa seeds have health-promoting activities include cardio-protective, antidiabetic, anticancer effects. Given paramount importance their oils potential...

10.1186/s42269-023-01161-3 article EN cc-by Bulletin of the National Research Centre/Bulletin of the National Research Center 2024-01-05

Methotrexate (MTX) has been used in high doses for cancer therapy and low autoimmune diseases. It is proven that methotrexate-induced hepatotoxicity occurs even at relatively doses. known garden cress anti-inflammatory, antioxidant, hepatoprotective properties. This study investigates the potential alleviating effect of oil (GCO) against MTX-induced rats. The chemical composition GCO was assessed using GC/MS analysis. Liver damage studied biomarkers, molecular, histological Also, effects on...

10.1038/s41598-025-89550-8 article EN cc-by Scientific Reports 2025-02-20

Microalgae provide a wealthy natural resource of bioactive compounds, which have many biological activities. Monosodium glutamate is food additive that acts either as preservatives or tastiness enhancer. It was confirmed monosodium poses serious responsibility in the pathogenesis anovulatory infertility. Therefore, idea this research directed to reveal efficiency Chlorella vulgaris and Spirulina platensis extracts against ovarian dysfunction resulted due consumption. Adult female albino mice...

10.1016/j.jgeb.2018.05.001 article EN cc-by-nc-nd Journal of Genetic Engineering and Biotechnology 2018-06-28

This study was designed to evaluate the oxidative damage, genotoxicity, and DNA damage in liver of rats treated with titanium nanoparticles (TiO2-NPs) an average size 28.0 nm ξ-potential - 33.97 mV, estimate protective role holy basil essential oil nanoemulsion (HBEON). Six groups Male Sprague-Dawley were orally for 3 weeks as follows: control group, HBEO or HBEON-treated (5 mg/kg b.w), TiO2-NPs-treated group (50 TiO2-NPs plus HBEON. Samples blood tissues collected different analyses. The...

10.1007/s12011-022-03228-0 article EN cc-by Biological Trace Element Research 2022-04-13

Chia oil is high in omega-3 fatty acids, which have been linked to a lower risk of many diseases, including cancer. Oil encapsulation method that holds promise for maintaining content while enhancing solubility and stability. The purpose this study prepare nanoencapsulated investigate its suppressive effects on rat chemically induced breast cancer.The was extracted from commercial seeds their acids were analyzed using Gas Chromatography-mass spectrometry (GC/MS). Sodium alginate used as...

10.1007/s11033-022-07885-1 article EN cc-by Molecular Biology Reports 2022-09-05

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

10.4103/2394-5079.168078 article EN Hepatoma Research 2015-01-01

Decrease in the ozone layer leads to increase amount of dangerous ultraviolet radiation that reaches earth’s surface. Exposure tissue damage. This study aimed investigate possible protective effects curcumin on testicular damage induced by Ultraviolet Irradiation (UVR) histologically, histochemically and morphometrically. 60 albino rats were divide into 5 groups (twelve each) first group served as control. The second was exposed C rays for ½ an hour (900 joule) three consecutive days. third...

10.4172/2157-7099.1000159 article EN Journal of Cytology & Histology 2013-01-01

Antimicrobial Activity of Extracellularly Synthesized Silver Nanoparticles using Lactobacillus Species Obtained from VIZYLAC CapsulePratik R. Chaudhari,Shalaka A. Masurkar, Vrishali B. Shidore, Suresh P. Kamble

10.7324/japs.2017.70204 article EN Journal of Applied Pharmaceutical Science 2017-01-01

Curcumin is a major component of the curcuma species, commonly used as yellow coloring and flavoring agent in foods.Curcumin has been demonstrated to have potent antioxidant, anti-inflammatory activity shown anticancer properties many rodent models.There perception that since compounds are natural, they devoid toxicity safe use.Some active supplements inherent toxicity.In this study, five doses (0.5, 5, 10, 25 50 mg/kg/daily) curcumin spice were orally administered male rats daily for four...

10.2495/etox060171 article EN WIT transactions on biomedicine and health 2006-08-24

Abstract Quinoa seeds ( Chenopodium quinoa Willd.) have grown in interest due to their naturally occurring phytochemicals and antioxidants. It was stated that it has a powerful anticancer effect against human colorectal cancer. Gas chromatography-mass spectrometry used analyze the oil fatty acids. Sodium alginate as loading agent encapsulating nanoemulsion, its acute oral toxicity assessed rats. The nanoemulsion's ability scavenge free radicals evaluated using DPPH radical-scavenging assay....

10.21203/rs.3.rs-4063717/v1 preprint EN cc-by Research Square (Research Square) 2024-03-15
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