A5060964592- Analytical Chemistry and Chromatography
- Carbon and Quantum Dots Applications
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Analytical chemistry methods development
- Antibiotics Pharmacokinetics and Efficacy
- Biochemical effects in animals
- Dye analysis and toxicity
- Antibiotic Resistance in Bacteria
- Advanced Chemical Sensor Technologies
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced Glycation End Products research
- Electrochemical Analysis and Applications
- Analytical Methods in Pharmaceuticals
- Molecular Sensors and Ion Detection
- Phytochemicals and Antioxidant Activities
- Luminescence and Fluorescent Materials
- Synthesis and Biological Evaluation
University of Sadat City
2022-2024
Mansoura University
2024
Green, one-pot, quick, and easily synthesized nitrogen sulfur co-doped carbon quantum dots (N,S-CDs) were obtained from cheap readily available chemicals (sucrose, urea, thiourea) using a microwave-assisted approach in about 4 min utilized as turn-off fluorescent sensor for estimation of natamycin (NAT). First, the effect N S doping on microwave-synthesized CDs' yield was carefully studied. CDs derived sucrose alone failed to produce high yield; then, increase yield, with heteroatoms carried...
Methylglyoxal (MGO) is a genotoxic α-dicarbonyl compound. Recently, it was found to be formed in glycerol preparations during storage through auto-oxidation. A simple fluorimetric determination of the carcinogenic degradation product glycerol, MGO, developed and validated. The proposed method based on derivatization MGO with 4-carbomethoxybenzaldehyde (CMBA) ammonium acetate yield fluorescent imidazole derivative that can measured at 415 nm after excitation 322 nm. optimized conditions were...
Abstract A green spectrofluorimetric method was introduced for the determination of selected genotoxic impurities; 2-aminopyridine and 3-aminopyridine in different pharmaceutical raw materials dosage forms. The relied on native fluorescence these impurities acidic medium. experimental conditions were carefully studied optimized, validated according to International Council Harmonisation (ICH) guidelines. linear range both analytes 2.50–100 ng/mL with good coefficients 0.9995 0.9992 detection...
Trace levels of cadmium, lead and mercury heavy metals are toxic to the human nervous system. These occur naturally as a result inappropriate agricultural industrial practices. In response this problem, novel modified electrode was constructed for simultaneous determination mercury. The prepared by incorporating zirconium oxide nanoparticles (ZrO 2 NPs) multi-walled carbon nanotubes (MWCNTs) into paste electrode. Transmission electron microscope electrochemical impedance spectroscopy were...
An innovative voltammetric sensor was developed to estimate omarigliptin, a novel long-acting anti-diabetic drug. The utilized carbon paste electrode enhanced with nanocomposite of nanotubes and electrodeposited gold nanoparticles. modified characterized using scanning electron microscopy electrochemical impedance spectroscopy. modification significantly improved the electrode’s sensitivity efficiency decreased its transfer resistance. surface area increased by about 2.8-fold compared bare...
Metformin is the most prescribed drug for diabetes.We aimed to develop a new HPLC method determination of metformin and its main impurity 1-cyanoguanidine in raw material pharmaceutical tablets.The separation was achieved on pentabromobenzyl column using mixture 20% 10.0 mM phosphate buffer (pH 5.5) 80% methanol as mobile phase at flow rate 1.0 mL min -1 UV detection 227 nm.The analysis time less than 4.0 minutes.The linear through concentration ranges 3.0 -80 µg 0.5-10 limits 0.73 0.11...