Zahra Shakeran

ORCID: 0000-0002-6829-870X
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About
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Research Areas
  • Transgenic Plants and Applications
  • Plant tissue culture and regeneration
  • Hepatitis B Virus Studies
  • Nanoparticles: synthesis and applications
  • Moringa oleifera research and applications
  • Nanoparticle-Based Drug Delivery
  • Hepatitis C virus research
  • RNA Interference and Gene Delivery
  • Drug-Induced Hepatotoxicity and Protection
  • Nanoplatforms for cancer theranostics
  • Medicinal Plant Research
  • Chromosomal and Genetic Variations
  • Seed Germination and Physiology
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Polymer Surface Interaction Studies
  • Essential Oils and Antimicrobial Activity
  • Advanced Biosensing Techniques and Applications
  • Bacteriophages and microbial interactions
  • Bee Products Chemical Analysis
  • Diverse Scientific Research Studies
  • Ethnobotanical and Medicinal Plants Studies
  • Virus-based gene therapy research
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced biosensing and bioanalysis techniques
  • Pomegranate: compositions and health benefits

University of Isfahan
2014-2024

Isfahan University of Technology
2020-2024

Aarhus University
2022

Hairy roots induced by Agrobacterium rhizogenes are distinguished their high growth rate, genetic stability, and lateral branching. Datura metel is an important medicinal plant whose hairy used for the production of atropine, a tropane alkaloid applied as anticholinergic parasympathetic agent. To increase yield biotic (Bacillus cereus Staphylococcus aureus) abiotic (AgNO_3 nanosilver) elicitors were added to root cultures D. then analyzed through high-performance liquid chromatography. All...

10.3906/biy-1405-25 article EN TURKISH JOURNAL OF BIOLOGY 2015-01-01

Nanocarriers have demonstrated promising potential in the delivery of various anticancer drugs and improving efficiency treatment. In this study, silver nanoparticles (AgNPs) were green-synthesized using extracts different parts pomegranate plant, including peel, flower petals, calyx. To obtain most efficient extract used for green synthesis AgNPs, all three types synthesized characterized. Then, (3-Aminopropyl) triethoxysilane-functionalized mesoporous silica (MSNs-APTES) decorated with...

10.1016/j.ejpb.2024.114349 article EN cc-by-nc-nd European Journal of Pharmaceutics and Biopharmaceutics 2024-06-05

Co-delivery of anticancer drugs and biologics can provide synergetic effects outperform single delivery therapies. Here, a nanoparticle (NP) system for co-delivery methotrexate (MTX) STAT3 siRNA has been developed tested in vitro. Mesoporous silica nanoparticles (MSNs) were functionalized with chitosan (ch) by covalent grafting mediated aminopropyl triethoxysilane (APTES) via glutaraldehyde as the linker. MTX to MCF7 cells was demonstrated flow cytometric analysis confocal laser scanning...

10.1080/21691401.2022.2030746 article EN cc-by Artificial Cells Nanomedicine and Biotechnology 2022-02-08

The (-)-hyoscyamine, atropine and scopolamine (hyoscine) are three valuable tropane alkaloids while is the most important member of this group for pharmaceutical industry due to its higher demand compared hyoscyamine atropine. Scopolamine an anticholinergic reagent with several therapeutic applications. In current study, hairy roots culture

10.22099/mbrc.2017.25776.1275 article EN PubMed 2017-12-01

Aims Diagnosis of Staphylococcus aureus is important in various diseases from hospital-acquired infections to foodborne diseases. This work reports two new luminescent affiprobes for specific detection S. aureus. Methods and Results To develop advanced affiprobes, enhanced green fluorescent protein (EGFP) was flanked by single double repeats ZpA963 affibody using molecular biology studies. The recombinant proteins including monomeric (fA1) dimeric (fA2) were expressed the bacterial...

10.1111/jam.14799 article EN Journal of Applied Microbiology 2020-08-01

Abstract Green synthesis methods are environmentally friendly, cost effective and nonhazardous for biomedical applications in comparison with other methods. The aim of the study was green silver nanoparticles using medicinal animal dung extract as a reducing, capping stabilizing agent first time among nanoparticles. Female donkey’s capable to reduce ions stabilize them. Silver average sizes 36 nm were synthesized characterized by UV-Vis, FT-IR, XRD TEM. Moreover, analyzed terms anticancer...

10.21203/rs.3.rs-412407/v1 preprint EN cc-by Research Square (Research Square) 2021-04-15
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