A5026173634- Microbial Inactivation Methods
- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Toxin Mechanisms and Immunotoxins
- Polyomavirus and related diseases
- Plant tissue culture and regeneration
- Cell Image Analysis Techniques
- Reconstructive Facial Surgery Techniques
- Plant Virus Research Studies
- Reconstructive Surgery and Microvascular Techniques
- Plant Disease Management Techniques
- Bacillus and Francisella bacterial research
- AI in cancer detection
- Electrostatic Discharge in Electronics
- Dermatologic Treatments and Research
- Surgical Sutures and Adhesives
- Digital Imaging in Medicine
- Surgical site infection prevention
- Cutaneous lymphoproliferative disorders research
- Vascular Tumors and Angiosarcomas
- Antenna Design and Analysis
- Microfluidic and Bio-sensing Technologies
- Diabetic Foot Ulcer Assessment and Management
- Melanoma and MAPK Pathways
- Sarcoma Diagnosis and Treatment
St George’s University Hospitals NHS Foundation Trust
2012-2024
St George's Hospital
2016-2023
St George's, University of London
2022
National Health Service
2022
St George's Hospital
2015-2016
South West London and St George's Mental Health NHS Trust
2012
London Clinic
2009
American Society of Plastic Surgeons
2005
Chelmsford and Essex Hospital
2005
Broomfield Hospital
2003
(ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery electrical pulses to tumour.To investigate effectiveness ECT in metastases melanoma and identify factors that affect (beneficially or adversely) outcome.Thirteen cancer centres International Network Sharing Practices on Electrochemotherapy consecutively prospectively uploaded data a common database. consisted intratumoral intravenous injection...
Background. Electrochemotherapy describes the use of electric pulses to enhance chemotherapy uptake, and has proven highly efficient in treating cutaneous metastases. Patients referred for electrochemotherapy present with diverse clinical pictures, from multiple small lesions large, ulcerated lesions. Post-electrochemotherapy pain been observed some patients. The objectives this study were evaluate scores before after electrochemotherapy, investigate if patients at risk post-procedure could...
Abstract Background Electrochemotherapy ( ECT ) is currently used to treat unresectable superficial tumours of different histotypes through the combination cytotoxic chemotherapy and local application electric pulses. In 2006, a collaborative project defined ESOPE (European Standard Operating Procedures Electrochemotherapy) guidelines standardize procedure. The International Network for Sharing Practices (Insp aims refine improve clinical practice. Limiting patient exposure systemic would be...
Introduction Cutaneous squamous cell carcinoma (cSCC) is a frequent skin cancer with high risk of recurrence characterized by tumor infiltration and, in advanced cases, poor prognosis. ECT (electrochemotherapy) an alternative treatment option for locally or recurrent cSCC that unsuitable surgical resection. In this study, we aimed to evaluate the data InspECT (International Network Sharing Practice on ECT) registry referral centers and clarify indications use as modality cSCC. Materials...
This prospective registry-based study aims to describe electrochemotherapy (ECT) modalities in basal cell carcinoma (BCC) patients and evaluate its efficacy, safety, predictive factors. The International Network for Sharing Practices of Electrochemotherapy (InspECT) multicentre database was queried BCC cases treated with bleomycin-ECT between 2008 2019 (n = 330 from seven countries, 623 BCCs [median number: 1/patient; range: 1-7; size: 13 mm, 5-350; 85% were primary, 80% located the head...
Electrochemotherapy has been proven to be an efficient treatment for cutaneous metastases of various cancers. Data on breast cancer (BC) patients with were retrieved from the INSPECT database. Patients divided by their receptor status: HER2+, HR+ (ER/PgR+), and TN (triple negative). Groups similar histological subtype location nodules. Most previously treated surgery/systemic therapy/radiotherapy. We found no differences in three groups terms response ratio (OR per patient 86% 80% HR+, 76%...
Skin metastases are an important co-morbidity in melanoma. Despite broad adoption, electrochemotherapy implementation is hindered by a lack of treatment indications, uncertainty regarding procedural aspects, and the absence quality indicators. An expert consensus may harmonize approach among centres facilitate comparison with other therapies.An interdisciplinary panel was recruited for three-round e-Delphi survey. A literature-based 113-item questionnaire proposed to 160 professionals from...
Electrochemotherapy (ECT) is an effective local treatment for cutaneous tumors. The aim of this study was to compare the effectiveness ECT in ulcerated vs. non-ulcerated tumors and investigate effect on tumor-associated symptoms.Twenty cancer centers International Network Sharing Practices (InspECT) prospectively collected data. performed following ESOPE protocol. Response evaluated by lesion size development. Pain, symptoms, performance status (ECOG-Index) health (EQ-5D questionnaire) were...
Electrochemotherapy (ECT) effectively controls skin metastases from cutaneous melanoma.
Abstract Basal cell carcinoma (BCC) is an increasingly common cancer. For high-risk BCCs, there are several treatment options, with similar efficacies. The current best practice in deciding upon a particular for patient-centred approach. At present, few resources available patients to assist their choice. This reduces patient autonomy and increases the burden on clinicians within clinic. Patient decision aids (PDAs) have been shown increase facilitate shared decision-making. Currently, no...
Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma with an indolent early course that may be misdiagnosed for benign skin pathology. In this case-report we highlight instance of DFSP arising from keloid scar de novo and present reconstruction local pedicled LD flap. We subsequently appraise the related literature discuss diagnostic challenges.