A5022385837- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Cardiovascular Health and Risk Factors
- Vaccine Coverage and Hesitancy
- Global Public Health Policies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Diabetes and associated disorders
- COVID-19 epidemiological studies
- Lipoproteins and Cardiovascular Health
- Health Promotion and Cardiovascular Prevention
- Climate Change and Health Impacts
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diabetes Management and Education
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Health disparities and outcomes
- Aging, Health, and Disability
- Long-Term Effects of COVID-19
- Adipokines, Inflammation, and Metabolic Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Body Composition Measurement Techniques
- Frailty in Older Adults
- Dietary Effects on Health
Instituto Nacional de Pediatria
2022-2025
Universidad Nacional Autónoma de México
2022-2025
NIMS University
2023
Post-acute sequelae after SARS-CoV-2 infection (PASC) remains a concerning long-term complication of COVID-19. Here, we aimed to characterize the epidemiology PASC in Mexico during 2022 and identify potential associations covariates with prevalence using nationally representative data. We analyzed data from Mexican National Health Nutrition Survey (ENSANUT) 24,434 participants, representing 85,521,661 adults ≥20 years. was defined both Institute for Care Excellence (NICE) definition score...
To estimate diabetes-related mortality in Mexico 2020 compared with 2017-2019 after the onset of coronavirus disease 2019 (COVID-19) pandemic.This retrospective, state-level study used national death registries Mexican adults aged ≥20 years for 2017-2020 period. Diabetes-related was defined using ICD-10 codes listing diabetes as primary cause death, excluding certificates COVID-19 death. Spatial and negative binomial regression models were to characterize geographic distribution...
Abstract Background In 2020, Mexico experienced one of the highest rates excess mortality globally. However, extent non-COVID deaths on mortality, its regional distribution and association between socio-demographic inequalities have not been characterized. Methods We conducted a retrospective municipal individual-level study using 1 069 174 death certificates to analyse COVID-19 non-COVID-19 classified by ICD-10 codes. Excess was estimated as increase in cause-specific 2020 compared with...
Vaccination has been effective in ameliorating the impact of COVID-19. Here, we report vaccine effectiveness (VE) nationally available COVID-19 vaccines Mexico.
With the widespread transmission of Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored role immunity, primary infection severity, and variant predominance in risk reinfection severe COVID-19 during Mexico.
Abstract Background Prediabetes has been associated with increased all-cause and cardiovascular mortality. However, no large-scale studies have conducted in Mexico or Latin America examining these associations. Methods We analyzed data from 114,062 adults without diabetes (diagnosed undiagnosed) the City Prospective Study. Participants were followed until January 1st, 2021, for cause-specific defined prediabetes according to American Diabetes Association (ADA, HbA1c ≥5.7% <6.5%)...
Differences in the prevalence of four diabetes subgroups have been reported Mexico compared to other populations, but factors that may contribute these differences are poorly understood. Here, we estimate and evaluate their correlates with indicators social disadvantage using data from national representative surveys.
ABSTRACT OBJECTIVE To characterize the epidemiology of post-acute sequelae after SARS-CoV-2 infection (PASC) in Mexico during 2022 and identify potential predictors PASC prevalence using nationally representative data. METHODS We analyzed data from Mexican National Health Nutrition Survey (ENSANUT) totaling 24,434 participants, representing 85,521,661 adults ≥20 years. was defined both World Organization definition a score ≥12. Estimates were stratified by age, sex, rural vs. urban setting,...
Abstract Aging is believed to occur across multiple domains, one of which body composition; however, attempts integrate it into biological age (BA) have been limited. Here, we consider the sex‐dependent role anthropometry for prediction 10‐year all‐cause mortality using data from 18,794 NHANES participants generate and validate a new BA metric. Our data‐driven approach pointed sex‐specific contributors estimation: WHtR, arm thigh circumferences men; weight, circumference, subscapular triceps...
Characterizing prediabetes phenotypes may be useful in guiding diabetes prevention efforts; however, heterogeneous criteria to define have led inconsistent prevalence estimates, particularly low- and middle-income countries. Here, we estimated trends Mexico across different definitions their association with prevalent cardiometabolic conditions.We conducted a serial cross-sectional analysis of National Health Nutrition Surveys (2016-2022), totalling 22 081 Mexican adults. After excluding...
ABSTRACT BACKGROUND Vaccination has been effective in ameliorating the impact of COVID-19. However, estimation vaccine effectiveness (VE) is still unavailable for some widely used vaccines and underrepresented groups. Here, we report on a nation-wide COVID-19 vaccination program Mexico. METHODS We test-negative design within national surveillance system to assess VE BNT162b2, mRNA-12732, Gam-COVID-Vac, Ad5-nCoV, Ad26.COV2.S, ChAdOx1 CoronaVac vaccines, against SARS-CoV-2 infection, related...
Evidence from low- and middle-income countries regarding the effect of smoking in people with diabetes is lacking. Here, we report association mortality a large cohort Mexican adults diabetes. Participants mellitus (self-reported diagnosis, use antidiabetic medications or HbA1c ≥ 6.5%) aged 35–74 years when recruited into Mexico City Prospective Study were included. Cox regression confounder-adjusted rate ratios (RRs) associated baseline status estimated. Among 15,975 women 8225 men but no...
ABSTRACT BACKGROUND Excess all-cause mortality rates in Mexico 2020 during the COVID-19 pandemic were among highest globally. Recent reports suggest that diabetes-related deaths also higher, but contribution of diabetes as a cause excess compared to prior years has not yet been characterized. METHODS We conducted retrospective, state-level study using national death registries from Mexican adults ≥20 for 2017-2020 period. Diabetes-related classified ICD-10 codes listed primary death,...
ABSTRACT BACKGROUND With widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored role hybrid immunity, primary infection severity, and variant predominance on risk reinfection severe COVID-19 during periods in Mexico. METHODS We analyzed Mexico individuals with ≥90 days from a previous using national surveillance registry cases March 3 rd , 2020, until August 13 th 2022. Immunity-generating events included infection, partial...
Prediabetes has been associated with increased all-cause and cardiovascular mortality. However, no large-scale studies have conducted in Mexico or Latin America examining these associations.
To validate AnthropoAge, a new metric of biological age (BA), for prediction all-cause mortality and age-related outcomes characterize population-specific aging patterns using multinational longitudinal cohorts.
ABSTRACT OBJECTIVE Older adults have heterogeneous aging rates. Here, we explored the impact of biological age (BA) and accelerated on frailty in community-dwelling older adults. METHODS We assessed 735 from Coyocan Cohort. BA was measured using AnthropoAge, with AnthropoAgeAccel, both Fried’s phenotype index. association (AnthropoAgeAccel ≥0) at baseline characterized body composition physical function. also as a risk factor for progression after 3-years follow-up. RESULTS higher prevalence...
ABSTRACT BACKGROUND Effective cardiovascular disease (CVD) risk management is a cornerstone of optimal diabetes care. Here, we estimated the prevalence and determinants CVD factor control amongst individuals with diagnosed in Mexico. METHODS We analyzed data from ≥20 years 2016-2023 Mexican National Health Nutrition Surveys. glycemic, blood pressure (BP), non-current smoking, combined control. LDL-C was assessed using SCORE2-Diabetes categories. BP-lowering, cholesterol-lowering,...
Older adults have highly heterogeneous aging rates.
ABSTRACT BACKGROUND Remnant cholesterol (RC) and insulin resistance (IR) have been independently associated with cardiovascular risk. OBJECTIVES We evaluated the mediating role of IR in risk conferred by RC on atherosclerotic disease (ASCVD) mortality. METHODS Analysis National Health Nutrition Examination Survey (NHANES-III/IV), including 16,201 individuals ≥20 years without diabetes complete mortality data. levels were calculated using total cholesterol, non-HDL-c, LDL-c estimated...
ABSTRACT OBJECTIVE Characterizing prediabetes phenotypes may be useful in guiding diabetes prevention efforts; however, heterogeneous criteria to define have led inconsistent prevalence estimates, particularly low- and middle-income countries. We estimated trends untreated Mexico across different definitions its association with prevalent cardiometabolic conditions. METHODS conducted a serial cross-sectional analysis of National Health Nutrition Surveys (2016-2021), totaling 21,442 Mexican...
Background: Cigarette smoking increases the already elevated risk of mortality observed in adults with type 2 diabetes but prospective data on association between and among Mexican are lacking. Methods: We analyzed from MCPS, which surveyed 150,000 1998-2004. performed Cox proportional hazard models Fine Gray sub distribution to estimate adjusted relative for all-cause cause-specific mortality, respectively. Results: Among 25,141 individuals diabetes, 50.7% were never smokers, 26% former...
Background: Identifying phenotypes at risk of diabetes may be useful in guiding prevention efforts. Here, we estimated the prevalence glucose metabolism disturbances Mexico and association different prediabetes criteria with cardiometabolic conditions. Methods: We conducted a serial cross-sectional analysis National Health Nutrition Surveys (2016-2021), excluding individuals diagnosed or undiagnosed diabetes. Prediabetes was defined using ADA (FPG 100-125 mg/dL and/or HbA1c 5.7-6.4%), WHO...
Background: Diabetes subgroups are a promising framework for characterizing diabetes heterogeneity but data on the epidemiology and sociodemographic profile of these in Mexican population sparse. Methods: We conducted serial cross-sectional analysis National Health Nutrition Survey Mexico (2016-2021). (obesity related [MOD], severe-insulin deficient [SIID], resistant [SIRD], age-related [MARD]) were classified using self-normalizing neural networks HbA1c, time since diagnosis, HOMA2-IR,...