A new type of coronavirus named as SARS-CoV-2 pandemic has begun to threaten human health. As with other types coronaviruses, affects children less frequently, and it been observed that the disease is mild. In pathogenesis a standard viral infection, pathogen's contact mucosa initially followed by an innate immunity response. T cells are primary decisive element in adaptive capability. For this reason, immune response mediated thymus process regulates responsible for preventing invasive...

Aim Nutritional B12 deficiency is a treatable cause of neurodevelopmental delay in infants. We report 21 infants with developmental regression and brain atrophy as revealed using cranial magnetic resonance imaging (MRI), secondary to severe vitamin deficiency. Methods Twenty‐one aged 4–24 months deficiencies who were admitted our clinic between May 2013 2018 included the study. MRI, bone marrow aspiration Denver‐II Developmental Screening Test performed all Results The mean age was 12.3...

Abstract Introduction: Obesity is usually related to insulin resistance and glucose metabolism disorders. The relationship between epicardial adipose tissue atrial electromechanical delay has been described in previous studies. Aim: This study aims demonstrate the effects of metformin on patients using for resistance. Materials methods: A total 30 were included study. Pre-treatment post-treatment evaluated. Results: There was a statistically significant decrease thickness after 3 months...

Neonatal sepsis is a clinical condition that results in serious morbidity and mortality unless urgently diagnosed treated. Obtaining the of blood cultures to determine causative agent time-consuming process. The CRP/albumin ratio an inflammatory marker has started be used recent years. aim our study was investigate relationship between Gram-negative bacterial neonates.This conducted on 112 premature neonates with sepsis. patients were divided into two groups according culture as...

Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematous lesions. The aim of this study to evaluate the moisture sebum content infants with AD its relationship between disease severity.For cross-sectional case-control we included 49 aged 2 24 months 34 healthy same age sex as control group. Skin were measured bio- impedance method recorded. prick tests, total IgE levels food-specific (milk, egg) performed.There was significant...

Background and Objective: Childhood obesity is one of the worldwide health problems with an increasing prevalence accompanied by severe morbidity mortality. It a serious predisposing risk factor especially for development cardiovascular diseases arrhythmias. Electromechanical delay (EMD) known to be predictor atrial fibrillation (AF). Our study aims investigate whether EMD, which AF, prolongs in obese children or not.The included 59 patients aged between 8-18 years 38 healthy as control...

The prevalence of childhood obesity is increasing and leads to co-morbidities such as hypertension. However, it still not clear why some obese individuals are hypertensive others not. Nesfatin-1 a recently discovered anorexigenic peptide which also has effects on blood pressure (BP). Our aim was evaluate the relationship between obesity-related hypertension Nesfatin-1.This cross-sectional study comprised 87 children. patients were divided into two groups; (n=30) normotensive (n=57) obese....

Kırık S, Güneş H, Yurttutan Sarışık N, Acıpayam C, Y. Hemophagocytic lymphohistiocytosis associated with oxcarbazepine. Turk J Pediatr 2019; 61: 297-300. (HLH) is a rare life-threatening multisystem disorder. Reports of the disorder as side effect drugs are extremely rare. We report case 3-year-old boy history epileptic seizures in which oxcarbazepine was added to treatment for last 35 days and dose had been increased. For 10 he fever, hepatosplenomegaly, rash, edema other systemic symptoms....

Background: There are limited efficacy and safety data for buprenorphine/naloxone treatment in adolescents, little is known about the incidence prevalence of liver function abnormalities young patients using buprenorphine/naloxone. Objectives: To assess changes enzyme levels associated with co-medication psychotropic agents among opioid dependent subjects aged 15–18 years. Methods: Liver (ALT AST) were evaluated 59 adolescent before following eight weeks treatment. Results: The frequency...

The aim of this study was to examine the effects atomoxetine on heart rhythm using 12-lead electrocardiography (ECG) and 24 h Holter monitoring.Children adolescents who were diagnosed with attention deficit-hyperactivity disorder according DSM-IV-TR referred a pediatric cardiology clinic for cardiologic examination before after 4 or 5 weeks treatment. Cardiac examination, complete blood count, biochemistry, thyroid function tests, ECG monitoring performed routinely in all patients. Each...

Objective To investigate the relationship between brain masculinization and retinal thickness in children with congenital adrenal hyperplasia (CAH). Methods Forty-five patients CAH aged 4 18 years 30 age-matched healthy controls were included this prospective study. Macular area was examined optical coherence tomography (OCT); central subfield (CST), cube volume (CV) macular (MT) measured each subject. A gender identity questionnaire (GIQ) used for evaluation of happiness index. Results...

Resumo Fundamentos A resistência à insulina (RI) é um distúrbio importante em crianças obesas, pois está intimamente relacionado a doenças cardiovasculares. O tecido adiposo epicárdico (TAE) desempenha papel no desenvolvimento da RI devido moléculas bioativas secretadas, sendo que o processo inflamatório dessas pode causar atraso eletromecânico atrial (AEA). Objetivo objetivo do nosso estudo foi determinar relação entre TAE e AEA com obesas. Métodos incluiu 94 pacientes obesos. IR calculada...

Background/aim: Necrotizing enterocolitis (NEC) is a commonly seen life-threatening condition in newborns characterized by ischemic necrosis. This study aimed to investigate anakinra's effects, an interleukin-1 receptor antagonist, on oxidative stress, inflammation, and tissue necrosis NEC rat model. Materials methods: Forty Wistar albino pups were divided into four groups randomly as follows; group 1, control group; 2, anakinra-treated 3, 4, anakinra treatment group. The rats given...

Abstract This study aimed to investigate anxiety, depression levels, and emotional/behavioral problems of children adolescents while being treated in the COVID-19 unit. The present included 50 who were positive, aged 7–18 years, age- gender-matched healthy controls. sociodemographic data form Revised Child Anxiety Depression Scale–Child Version (RCADS-C) applied all children, families asked form, Scale–Parent (RCADS-P), Strengths Difficulties Questionnaire (SDQ). There was no significant...

Introduction: Upper respiratory tract infections (URTI) are the most common of childhood. The purpose our study is to develop a clinical scoring method distinguish viral and bacterial in patients who were diagnosed with URTI. Methods: This was conducted pediatric 220 URTI whose ages between 5 15. previous studies about nonbacterial reviewed determine signs symptoms evaluate study. These signs, throat swab culture results recorded. Results: Throat positive at 93 (42%). According this clinic...

Aim: Familial Mediterranean fever (FMF); is an auto-inflammatory disease characterized by recurrent attacks. Inflammation continues even in the attack-free period. Monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) inflammatory marker that has recently begun use. The aim of study was evaluate relationship between MHR and FMF children. Material Methods: Sixty-two children with period 60-age sex-matched- healthy controls included study. Patients divided into subgroups...

Aim: A thrombosis and inflammation marker, Signal peptide-CUB (complement C1r/C1 s)-EGF (epidermal growth factor)-like domain-containing protein 1 (SCUBE-1) is expressed in endothelial cells activated platelets. We aimed to investigate the levels of this marker patients with Thalassemia major (TM), a disease which causes tendency thrombosis.Methods: Twenty TM age gender-matched twenty healthy controls were included prospective case-control study. Other markers such as D-dimer homocysteine...

Gender identity, psychosexual function, psychiatric adjustment and quality of life have been investigated in congenital adrenal hyperplasia(CAH) patients.We aimed to investigate gender identity problems the disorders associated factors children adolescents with CAH patients.Forty-five were included study. Psychiatric comorbidity was assessed using Schedule for Affective Disorders Schizophrenia School Age Children - Present Lifetime Version. Diagnostic Statistical Manual Mental Disorders,...

Klippel-Trenaunay Weber Sendromu (KTWS) kutanöz vasküler malformasyonlar, kemik ve yumuşak doku hipertrofisi varisli damarlar ile karakterize konjenital bir sendromdur. KTWS'de hem periferik de viseral tutulum görülebilir bu önemli morbidite mortalite kaynağı olabilir. Pulmoner emboli, tromboflebit, kanama, staz dermatiti ülserasyon gibi komplikasyonların önlenmesinde erken tanı önemlidir. Kliniğimize olası KTWS tanısı 9 günlük yenidoğan sunuldu. Çocuklukta hastalığın teşhisi önemlidir venöz...

Amaç: Akut Gastroenteritler (AGE) çocukluk çağının sık görülen enfeksiyonlarındandır. Çalışmamızın amacı AGE tanısıyla kliniğe yatırılan vakaların klinik bulgularını ve laboratuvar değerlerini incelemektir. Gereç Yöntem: Çalışmamıza kliniğimizde Ocak 2016 2019 tarihleri arasında yatan 0-17 yaş aralığında, ishali 14 gün veya daha kısa süreli olan 130 hasta alındı. Hastalar, etkenlere göre paraziter viral AGE'li olmak üzere iki gruba ayrıldı. Hastaların demografik, verileri dosyalarından elde...

Amaç: Maraş otu (MO), tütün türlerinden olan Nicotina Rustica L. yaprakları ile meşe ve asma odunun küllerinden elde edilen, ağızda çiğnenerek kullanılan toz formunda dumansız ürünlerindendir. Bölgemizde halk arasında yaygın kullanımından dolayı çocuk vakaların erişimi kolay olmakta özellikle küçük yaş gruplarında ciddi intoksikasyon kliniği hastalar acilimize başvurmaktadırlar. Çalışmamızın amacı, acil servisimize MO’ ya bağlı zehirlenme başvuran olguların değerlendirilmesi genel hatları bu...

The authors declare no conflict of interest.