A procedure was developed for in vitro propagation of Curculigo latifolia through shoot tip culture. Direct regeneration and indirect scalp induction were obtained from grown on MS medium supplemented with different concentrations combinations thidiazuron indole-3-butyric acid. Maximum response direct terms percentage explants producing shoot, number, length combination (0.5 mg L −1 ) acid (0.25 after both 10 14 weeks cultures. Indole-3-butyric exhibited a synergistic effect regeneration....

Curculin, which is extracted from fruits of Curculigo latifolia has been found to have a sweet taste with sweetness-modifying characteristics of natural sweeteners and has shown be good low-calorie sweetener. In vitro growth performance of C. latifolia cultures limited by contamination browning. This study was aimed minimize the effect phenolic components, eliminate identify suitable explants for in vitroregeneration latifolia. Our results showed that use ascorbic acid, citric...

Interleukin 12 (IL-12) is considered as an important molecule for cancer immunotherapy with significant roles in hindering tumor activity, mostly mediated by tumor-associated macrophages and anti-angiogenic factors. Mesenchymal stem cells (MSCs) have been come out promising carriers to increase the accumulation of drug/gene sites. As a vehicle, MSCs various advantages, including tumor-specific propensity migratory ability; however, they limited transfection efficiency, compared other cells....

Curculin, a sweet protein found in Curculigo latifolia fruit has great potential for the pharmaceutical industry. This interestingly been to have both taste and taste-modifying capacities comparable with other natural sweeteners. According our knowledge this is first reported case on isolation of microsatellite loci genus. Hence, current development markers C. will facilitate future population genetic studies breeding programs valuable plant. In study 11 were developed using 3' 5' ISSR...

Parkinson's disease (PD) is a severely debilitating for which no suitable treatment has been found so far. In recent years, nanoparticles (NPs) have shown therapeutic potential in PD. Thus, the current research, first time, we investigated effects of vitamin E and TiO2 (TiO2-NPs) on rat model PD.In this experimental study, after preparation induction PD, rats were administrated with TiO2-NPs. One day receiving last dose treatments, killed substantia nigra was extracted from brain its cell...

Ulcerative colitis (UC), a common gastrointestinal disorder in affluent nations, involves chronic intestinal mucosal inflammation. This research investigated the effects of combined probiotic treatment

Abstract Objectives Ulcerative colitis (UC) is a common gastrointestinal (GI) disorder characterized by chronic inflammation. Current treatments primarily focus on symptom management, but they have inherent limitations. Global attention increasingly directed towards exploring herbal remedies as complementary approaches. This study aims to investigate the effects of hydroalcoholic extract jujuba an experimental model ulcerative colitis. Methods In this study, 15 male BALB/c mice were divided...

Background: One of the most important factors in reducing birth rate is male infertility, and one main reasons for infertility scrotal hyperthermia (SH). Therefore, this study aimed to investigate protective effect coenzyme Q10 (CoQ10) along with Fe2O3 nanoparticles on semen parameters rats SH. Materials Methods: Forty-eight adult Wistar were divided into eight groups: healthy control, control group receiving nanoparticles, CoQ10, plus SH group, nanoparticle, CoQ10. After killing rats, was...

The effect of an extremely low-frequency magnetic field (ELF-MFs) on the expression levels NOTCH1 and its regulatory circular RNA (circ-RNA) in gastric cancer has not yet investigated. This study aimed to find changes circ-RNA, hsa_circ_0005986, human adenocarcinoma cell line (AGS) normal fibroblast (Hu02) cells fallowing exposure discontinuously flux densities (MFDs) 0.25, 0.5 ,1 2 millitesla (mT) for 18h comparison unexposed cells. In addition, various MFDs viability tumor was evaluated by...

Two Bacillus subtilis strains L10 and G1, previously isolated from fermented pickles, were tested for antibacterial activity against Vibrio harveyi using a well-diffusion agar assay. Antibiotic biosynthesis genes then detected in both bacterial included the following genes: bacA, bacB bacD bacilysin production, ppsE/fenB gene plipastatin/fengycin albF albA subtilosin srfAB sfP surfactin production. Based on these results, two B. could be considered as potential biological control agents aquaculture.

Extremely low-frequency magnetic field (ELF-MF) exposure, as a targeted tumor therapy, presents several potential advantages. In this research, we investigated effects of different ELF-MF intensities on cell viability and expression levels the mammalian target rapamycin (mTOR) hsa_circ_100338 in normal fibroblast (Hu02) human gastric adenocarcinoma (AGS) lines.In experimental study, lines AGS Hu02, were cultured under exposure ELFMF with flux densities (MFDs) 0.25, 0.5, 1 2 millitesla (mT)...

This study was carried out to evaluate 40 kenaf accessions for forage yield and quality at Universiti Putra Malaysia in 2009. Forage traits were measured the initial flowering stage. The showed highly significant variation most of trait studied. Plant dry matter ranged from 5286 kg ha-1 (Everglade 41) 16801 (IX51). Crude protein content leaf 13.6% (G46) 22.3% (75-71) it higher than stem which is 2.7 % (FDW-75-8) 7.5 (K465/117). Leaf ADF significantly different among accessions, where FDW...

Cervical cancer (CC) is a common among women, often treated with Doxorubicin (Doxo). Research underway to explore the use of oncolytic virus (OV) therapy as means improve drug efficacy and enhance immune system's tumor-fighting capabilities. Hence, our study purposes evaluate therapeutic potential Newcastle disease (NDV) in increasing antitumor Doxo mouse models CC. TC1 cells were administered C57BL/6 mice (Female) range 6 8 weeks age (n = 40) induce tumor growth. After development, four...

Background: Attention to the electromagnetic exposure as a targeted tumor therapy has been recently increasing. Objectives: The aim of current study was investigate effect continuous and discontinuous fields on cell viability well phosphatase tensin homolog (PTEN) circular (circ)-RNA CDR1as genes expression in normal gastric cancer (GC) lines. Methods: After preparing lines (AGS) cells (HU02 line), they were exposed magnetic flux densities 0.25, 0.5, 1, 2 mT continuously discontinuously (1h...