A5014598123- Bone Tissue Engineering Materials
- Laser-Ablation Synthesis of Nanoparticles
- 3D Printing in Biomedical Research
- Bacterial biofilms and quorum sensing
- Antimicrobial agents and applications
- Electrospun Nanofibers in Biomedical Applications
- Laser Applications in Dentistry and Medicine
- Cellular Mechanics and Interactions
- Dental materials and restorations
- Dental Implant Techniques and Outcomes
RMIT University
2021-2024
This paper presents the development of advanced Ti implants with enhanced antibacterial activity. The were engineered using additive manufacturing three-dimensional (3D) printing technology followed by surface modification electrochemical anodization and hydrothermal etching, to create unique hierarchical micro/nanosurface topographies microspheres covered sharp nanopillars that can mechanically kill bacteria in contact surface. To achieve performance, fabricated implant models loaded...
Abstract Nanostructured surfaces are effective at physically killing bacterial cells, highlighting their prospective application as biomaterials. The benefits of mechano‐bactericidal nanostructures an alternative to chemical functionalisation well documented, however, the effects protein adsorption not understood. In this work, theoretical and experimental analyses conducted by studying human serum proteins (HSP) nanosheet titanium (Ti) its subsequent effect on efficacy toward Staphylococcus...
Despite recent advances in the development of orthopedic devices, implant-related failures that occur as a result poor osseointegration and nosocomial infection are frequent. In this study, we developed multiscale titanium (Ti) surface topography promotes both osteogenic mechano-bactericidal activity using simple two-step fabrication approach. The response MG-63 osteoblast-like cells antibacterial toward Pseudomonas aeruginosa Staphylococcus aureus bacteria was compared for two distinct...
Bactericidal Nanostructured Titanium Surfaces Antibacterial biomimetic nanostructures coated in human serum proteins (shown blue), effectively eliminate Staphylococcus aureus bacteria (highlighted red). The potent bactericidal action of these prompts the release anti-inflammatory cytokines by macrophage cells green), fostering a healing-associated M2 polarization when cultured on pre-infected with pathogenic bacteria. More details can be found article 2301021 Denver P. Linklater, Vladimir A....