Franco Iafrate

ORCID: 0000-0002-6983-8624
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Research Areas
  • Colorectal Cancer Screening and Detection
  • Diverticular Disease and Complications
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Surgical Treatments
  • Genetic factors in colorectal cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Gastrointestinal disorders and treatments
  • Intraperitoneal and Appendiceal Malignancies
  • Colorectal and Anal Carcinomas
  • Gastrointestinal Tumor Research and Treatment
  • Advanced X-ray and CT Imaging
  • Appendicitis Diagnosis and Management
  • Ovarian cancer diagnosis and treatment
  • Colorectal Cancer Treatments and Studies
  • COVID-19 Clinical Research Studies
  • COVID-19 diagnosis using AI
  • Radiation Dose and Imaging
  • Long-Term Effects of COVID-19
  • Soft tissue tumor case studies
  • AI in cancer detection
  • Lung Cancer Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Esophageal Cancer Research and Treatment
  • Adrenal and Paraganglionic Tumors
  • Pancreatic and Hepatic Oncology Research

Sapienza University of Rome
2014-2024

Policlinico Umberto I
2013-2024

Ospedale Regina Margherita
2009

European Institute of Oncology
2001

University of Milan
2001

To correlate a CT-based semi-quantitative score of pulmonary involvement in COVID-19 pneumonia with clinical staging disease and laboratory findings. We also aimed to investigate whether CT findings may be predictive patients' outcome.

10.1007/s00330-020-07033-y article EN other-oa European Radiology 2020-07-04

In case of incomplete colonoscopy, several radiologic methods have traditionally been used, but more recently, capsule endoscopy was also shown to be accurate. Aim this study compare colon (CCE) and CT colonography (CTC) in a prospective cohort patients with colonoscopy.Consecutive previous colonoscopy underwent CCE CTC followed by positive findings on either test (polyps/mass lesions ≥6 mm). Clinical follow-up performed the other cases rule out missed cancer. after excretion or 10-12 h...

10.1136/gutjnl-2013-306550 article EN Gut 2014-06-24

So far, only a few studies evaluated the correlation between CT features and clinical outcome in patients with COVID-19 pneumonia.To evaluate ability differentiating critically ill requiring invasive ventilation from less severe disease.We retrospectively collected data admitted to our institution for pneumonia March 5th-24th. Patients were considered or non-critically ill, depending on need mechanical ventilation. images both groups analyzed assessment of qualitative disease extension,...

10.1016/j.ejrad.2020.109202 article EN other-oa European Journal of Radiology 2020-07-29

The objective of this study was to assess the clinical and economic impact colonoscopic referral for small diminutive polyps detected at CT colonography (CTC) screening.A decision analysis model constructed incorporating expected polyp distribution, advanced adenoma prevalence, colorectal cancer (CRC) risk, CTC performance, costs related CRC screening treatment. conservatively assumed that risk independent size. number (< or = 5 mm), (6-9 large (> 10 mm) CTC-detected needed be removed detect...

10.2214/ajr.07.2646 article EN American Journal of Roentgenology 2007-12-19

The primary aim of this model analysis was to compare the clinical and economic impacts immediate polypectomy versus 3-year CT colonography (CTC) surveillance for small (6- 9-mm) polyps detected at CTC screening.A decision constructed incorporating expected advanced neoplasia prevalence, frequency measurable growth, colorectal cancer (CRC) prevalence risk, performance, costs related CRC screening treatment. risk assumed be independent adenoma size, which intentionally overestimates polyps....

10.2214/ajr.08.1010 article EN American Journal of Roentgenology 2008-10-21

To assess the effect of computer-aided detection (CAD) as a second reader on sensitivity and specificity computed tomographic (CT) colonography in detecting 6-9-mm colorectal cancer (CRC) lesions.Individuals with clinical indications for colonoscopy--either symptoms or part participating surveillance program CRC screening--were prospectively enrolled at one 10 academic centers between July 2007 May 2009. Institutional review board approval was obtained each site, all participants provided...

10.1148/radiol.12120376 article EN Radiology 2012-11-14

To evaluate CT and laboratory changes in COVID-19 patients treated with tocilizumab, compared to a control group, throughout combined semiquantitative texture analysis of images. From March 11 April 20, 2020, 57 SARS-CoV-2 positive were retrospectively compared: group T (n = 30) receiving tocilizumab non-T 27) undergoing only antivirals/antimalarials. Chest-CT findings analyzed before after treatment. evaluation included both scoring all parenchymal lesions. Survival recovery analyses also...

10.1007/s11547-021-01371-7 article EN other-oa La radiologia medica 2021-06-05

Abstract Abdominal pain in patients with diverticular disease (DD) can be challenging clinical practice. Patients symptomatic uncomplicated (SUDD) and a previous acute diverticulitis (PD) may share similar pattern, difficult to differentiate from irritable bowel syndrome (IBS). We used standardized questionnaires for DD (short long lasting abdominal pain) IBS (following Rome III Criteria) assess features of pain, terms presence, severity length, SUDD PD patients. One hundred forty-eight 118...

10.1007/s11739-024-03588-6 article EN cc-by Internal and Emergency Medicine 2024-04-27

To identify the most useful areas for research in colorectal cancer (CRC) screening by using a value-of-information analysis.Cost-effectiveness of strategies, including colonoscopy, computed tomographic (CT) colonography, flexible sigmoidoscopy, and barium enema examination, were compared Markov model. Monetary net benefit (NB), measure cost-effectiveness, was calculated multiplying effect (life-years gained) willingness to pay (100,000 dollars per life-year subtracting cost. A analysis used...

10.1148/radiol.2533090234 article EN Radiology 2009-09-30

Background: The aim of the study was to longitudinally evaluate association between MMP-2, MMP-9, TIMP-1 and chest radiological findings in COVID-19 patients. Methods: patients were evaluated based on their hospital admission (baseline) three months after discharge (T post) stratified into ARDS non-ARDS groups. As a control group, healthy donors (HD) enrolled. Results: At baseline, compared HD (n = 53), 129) showed higher plasma levels MMP-9 (p &lt; 0.0001) activity MMP-2 0.0001). In 0.0339)...

10.3390/biom13071040 article EN cc-by Biomolecules 2023-06-26
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