- Mathematical and Theoretical Epidemiology and Ecology Models
- Nonlinear Dynamics and Pattern Formation
- Evolution and Genetic Dynamics
- Mathematical Biology Tumor Growth
- Geology and Paleoclimatology Research
- Planetary Science and Exploration
- Complex Systems and Time Series Analysis
- Marine and environmental studies
- Advanced Differential Equations and Dynamical Systems
- Stability and Controllability of Differential Equations
- Chemical Synthesis and Analysis
- Flame retardant materials and properties
- Neural Networks Stability and Synchronization
- Stability and Control of Uncertain Systems
- Electrospun Nanofibers in Biomedical Applications
- Spaceflight effects on biology
- Space Exploration and Technology
- Economic theories and models
- Soil Geostatistics and Mapping
- Gene Regulatory Network Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
- Linguistics and Cultural Studies
- Aquatic Invertebrate Ecology and Behavior
- Synthesis of β-Lactam Compounds
- Curcumin's Biomedical Applications
Eötvös Loránd University
2018-2024
Budapest University of Technology and Economics
2010-2024
Hungarian Academy of Sciences
2004-2020
Geographical Institute
2013-2018
Research Centre for Astronomy and Earth Sciences
2013-2018
Országos Reumatológiai és Fizioterápiás Intézet
2015
Danube Research Institute
2012
In this study a new intravenous (i.v.) bolus dosage form of doxycycline was prepared by electrospinning. A tetracycline-type antibiotic with low water solubility (doxycycline (DOX)) used 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) as solubilizer. The solid formulation could be produced high (~80 g/h) productivity rate using high-speed electrospinning (HSES) from water-based precursor solution. Freeze-dried DOX-HP-β-CD also the same solution HSES for comparison. Raman mapping showed that...
Abstract Flame retardant effect of newly synthesized phosphorus‐containing reactive amine, which can be used both as crosslinking agent in epoxy resins and flame retardant, was explored. The montmorillonite sepiolite additives on thermal stability retardancy compared the resin matrix. Copyright © 2006 John Wiley & Sons, Ltd.
The development of peptide-based pharmaceutics is a hot topic in the pharmaceutical industry and basic research. However, from research perspective there an unmet need for new, alternative, solid-phase peptide synthesizers that are highly efficient, automated, robust, able to synthetize peptides parallel, inexpensive (to obtain operate), have potential be scaled up, even comply with principles green chemistry. Moreover, synthesizer this type could also fill gap university research, therefore...
Chemotherapy is still one of the main therapeutic approaches in cancer therapy. Nevertheless, its poor selectivity causes severe toxic side effects that, together with development drug resistance tumor cells, results a limitation for application. Tumor-targeted delivery possible choice to overcome these drawbacks. As well as monoclonal antibodies, peptides are promising targeting moieties delivery. However, peptide–drug conjugates (PDCs) big challenge. The reason that have be stable...
Curcuminoids (CUs) of antitumor and various other potential biological activities have extremely low water solubility therefore special formulation was elaborated. New fast dissolving reconstitution dosage forms four CUs were prepared as fibrous form 2-hydroxypropyl-β-cyclodextin (HP-β-CD). In the electrospinning process HP-β-CD could act both solubilizer fiber-forming agent. The solubilization efficiency CU-HP-β-CD systems determined with phase-solubility measurements. electrospun amorphous...
The geomorphological characteristics of the loess succession at Malá nad Hronom (Slovakia) mean that it provides a valuable opportunity for investigation differences in soil formation various topographic positions. Along with semiquantitative characterization paleosols (on basis physical properties, texture, peds, clay films, horizon boundaries), high-resolution field magnetic susceptibility measurements and sampling were carried out along four different sections profile. Samples...