A5032142650- Genetic factors in colorectal cancer
- Breast Cancer Treatment Studies
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Advances in Oncology and Radiotherapy
- Radiomics and Machine Learning in Medical Imaging
- Nutrition and Health in Aging
- Colorectal Cancer Surgical Treatments
- Advanced Radiotherapy Techniques
- COVID-19 and healthcare impacts
- Advanced MRI Techniques and Applications
- Head and Neck Cancer Studies
- HER2/EGFR in Cancer Research
- Cancer and Skin Lesions
- Male Breast Health Studies
- Global Cancer Incidence and Screening
- Ultrasound and Hyperthermia Applications
- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Meningioma and schwannoma management
- Effects of Radiation Exposure
- Healthcare professionals’ stress and burnout
Alexandria University
2018-2024
King Fahd Medical City
2014
PURPOSE Early-onset colorectal cancer (EOCRC) is a rising health problem. The incidence of EOCRC has increased over the past 2 decades all world. Reports from Egypt since 1990s have reported higher among young populations with no identifiable risk factors. aim this study was to assess in regarding incidence, characteristics, treatment pattern, and survival compared average age onset elderly patients. MATERIALS AND METHODS This retrospective, record-based, cohort combining data four different...
KRAS mutation is widely accepted as a key factor in colorectal tumorigenesis. Although studied CRC limited data are available about rates and spectrum from developing countries like Saudi Arabia where epidemiological features of the disease different. We retrospectively tumor samples 83 metastatic patients for mutations codon 12 13, to evaluate relevance positive cancers with sites. was observed 42.2% (35/83) CRC. The most common were (p.G12D, 46%; 16/35, P < 0.0001), (pG12V, 31%; 11/35, 13...
K-ras gene mutations contribute to the pathogenesis of colorectal cancer. We characterized in tumors patients Kingdom Saudi Arabia, terms geographic area, age, gender, histology, stage, and anatomical localization.Medical records paraffin-embedded tumor samples from 150 consecutive with histologically proven adenocarcinoma referred two centers Arabia were analyzed using an LCD-array kit.K-ras occurred 56% patients; 48.7% codon 12, most commonly p.G12V p.G12D (each 35.6% 12 mutations). Codon...
Background: Central neurocytoma (CN) is a rare tumor accounting for <0.5% of all intracranial tumors. Surgery ± radiotherapy the mainstay treatment. This international multicentric study aims to evaluate outcomes CNs patients after multimodal therapies and identify predictive factors. Patients methods: We retrospectively identified 33 with CN treated between 2005 2019. Treatment characteristics were assessed. Results: All underwent surgical resection. Radiotherapy was delivered in 19...
This study aimed to assess the impact of oral nutritional supplements (ONS) on intake, body weight, and composition in head neck cancer (HNC) patients undergoing chemoradiotherapy. The evaluated whether ONS could prevent treatment-related deterioration. prospective observational pilot included 30 HNC randomized into two groups: (n = 15) No 15). All participants underwent chemoradiotherapy, with group receiving 200 mL a high-calorie, high-protein supplement twice daily. Nutritional status,...
Breast cancer in men accounts for approximately 1% of all breast cancers. trials have routinely excluded men. The aim this analysis was to determine the effect different treatment factors, particular, postoperative radiation therapy (RT) on long-term outcomes.Seventy-one patients with male treated 5 closely cooperating institutions between 2003 and 2019 were analyzed.Almost (95%) underwent surgical resection. Forty-two (59%) received chemotherapy, 59 (83%) adjuvant hormonal therapy. Of 71...
Background: Healthcare workers, including oncologists, face a higher potential risk of contracting coronavirus disease 2019 (COVID-19) while managing patients.Moreover, the uncertainty that came with COVID-19 and its associated social stigma may worsen what was already crisis (burnout) among oncologists.Data are scarce on impact occupational health safety oncologists in low middleincome countries. Methods:We conducted cross-sectional survey February 2021 to evaluate practicing Alexandria...
Objective The aim of this study is to identify possible clinical predictors complete response after neoadjuvant treatment (NAT) in locally advanced rectal cancer (LARC) patients. Materials and methods This included 40 LARC patients (16 males 24 females) who received NAT followed by total mesorectal excision (TME) the period between August 2020 February 2023. Two different protocols were used; long-course chemoradiotherapy (LCRT) or consolidation (TNT) according decision multidisciplinary...
Many studies have shown that Head and Neck Cancer (HNC) has high incidence of malnutrition; 20% to 67% HNC patients are malnourished at the time diagnosis or they risk becoming during treatment. The unique location, treatment modalities side effects radiotherapy such as oropharyngeal mucositis, xerostomia dysphagia a major role in developing malnutrition patients. Among various nutritional assessment methods anthropometric measurements, biochemical, clinical, dietary assessments, dual energy...
Abstract Purpose: Organs at risk sparing without compromising adequate coverage to the target volumes is main challenge during left breast cancer adjuvant radiation therapy. Advanced radiotherapy techniques have been investigated improve dose distributions and reduce toxicities. These includes deep inspiration breath hold, accelerated partial-breast irradiation, Intensity Modulated Radiation Therapy. Supine positioning (SP) most commonly used standard tangent set-up for radiotherapy. Our...
Abstract Background Breast cancer is the second most common in world and frequent among women. Tumor-infiltrating lymphocytes (TILs) can impact tumor progression response to therapies. Here we aimed study TILS using International Immunooncology Biomarkers Working Group guidelines correlating with clinicopathological characteristics, disease free overall survival non-metastatic breast patients. Methods Non metastatic patients (N = 86) who presented our department between (2013 - 2015) were...
e13514 Background: The unprecedented emergence of coronavirus disease (COVID-19) has disrupted the patients' and physicians' daily activities, including cancer care. However, little is known on how COVID-19 impacted oncologists from low middle-income countries. Methods: We conducted a cross-sectional survey among eighty-eight practicing in Alexandria governorate, Egypt. An electronic, anonymized self-reporting was distributed February 2020 to collect information occupational safety measures,...
Abstract Purpose: Exploration of the population profile and management female breast cancer in a representative sample from Alexandria, Egypt, to identify system inefficiencies barriers preventing full implementation international guidelines, negatively impacting outcome. Methods: The study surveyed 7125 records three major public oncology services at Main University Hospital, Gamal Abd-elnasser Hospital Ayadi Almostakbel Oncology Center, between 2007 2016. Results: 73.4% (5236 records)...