A5077516443- Protein Interaction Studies and Fluorescence Analysis
- Protein Structure and Dynamics
- Photosynthetic Processes and Mechanisms
- Metal complexes synthesis and properties
- Estrogen and related hormone effects
- Enzyme Structure and Function
- Metal-Catalyzed Oxygenation Mechanisms
- Drug Transport and Resistance Mechanisms
- Traditional Chinese Medicine Analysis
- Enzyme Catalysis and Immobilization
- Evaluation Methods in Various Fields
- Plant Stress Responses and Tolerance
- Lysosomal Storage Disorders Research
- Crystal structures of chemical compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Malware Detection Techniques
- HIV, Drug Use, Sexual Risk
- Multi-Criteria Decision Making
- Polymer-Based Agricultural Enhancements
- Pesticide and Herbicide Environmental Studies
- Fuzzy Logic and Control Systems
- Pharmacogenetics and Drug Metabolism
- Studies on Chitinases and Chitosanases
- Computational Drug Discovery Methods
- Invertebrate Immune Response Mechanisms
China Agricultural University
2019-2023
Jilin Vocational College of Industry and Technology
2022
Jiangxi Normal University
2012
Chinese People's Armed Police Force
2011
China People's Police University
2011
Hainan Normal University
2010-2011
The First People's Hospital of Changde
2010
CAE (Canada)
2010
Various strategies have been developed to improve the applicability of hydrophobic pesticides for better effectiveness in agriculture. However, existing formulations still suffer from complicated processing, abused organic solvents, indispensable surfactants, or inescapable ecotoxicity, which strictly limit their applications. Herein, a dynamic covalent bond tailored pesticide (fipronil) amphiphile is constructed address above issues, accomplishes nanodispersion, full wetting, and precise...
Chitin can be widely found in the fungal cell wall, nematode eggshells, and exoskeleton of arthropods; however, it is completely absent from higher plants mammals. The process chitin degradation essential for both growth maturation insects. Thus, inhibiting a promising strategy control management pests. chitinolytic β-N-acetyl-D-hexosaminidase OfHex1 Ostrinia furnacalis (one most destructive pests) has been suggested as potential target design eco-friendly pesticides. This study presents...
As a top-selling neonicotinoid insecticide widely used in the field, thiamethoxam is an environmental pollutant because of accumulation ecosystem and has also been reported that it potential risks to health mammals even humans. In order understand binding mechanism with biological receptors, spectroscopic techniques theoretical simulations was explore specific interactions between proteins. Interestingly, results indicated hydrophobic interaction as main driving force, formed single site...
This piece of study has done a serious work as following. Firstly, it discussed the method toward Intuitionistic Fuzzy Sets (IFS) approximate to Sets(FS) and related properties, which is based on relationships between IFS FS. Secondly, author also studied fuzzy complementary judgment matrix (IFCJM) approximates (FCJM), according basic consideration refer hesitation degree IFS. Moreover, regarding iteration process consistency adjustment FCJM, form IFCJM been given within via therefore...
Haloxyfop was reported to exhibit inhibition effect targeting Mycobacterium tuberculosis and pathogenic parasites. To pave its way for drug development, more research is required determine the affinities interacting with biological receptors in vivo. In this work, interactions of two model transport proteins were investigated by spectroscopic techniques theoretical simulation. The interaction mechanism, thermodynamic properties impact Haloxyfop-induced conformational change serum albumins...
β-N-acetyl-D-hexosaminidases have attracted significant attention due to their crucial role in diverse physiological functions including antibacterial synergists, pathogen defense, virus infection, lysosomal storage, and protein glycosylation. In particular, the GH3 β-N-acetyl-D-hexosaminidase of V. cholerae (VcNagZ), human GH20 B (HsHexB), GH84 (hOGA) are three important representative glycosidases. These been found be implicated β-lactam resistance storage disorders (HsHexB) Alzheimer's...
Herbicide resistance is a prevalent problem that has posed foremost challenge to crop production worldwide. Light-dependent enzyme NADPH: protochlorophyllide oxidoreductase (LPOR) in plants metabolic target could satisfy this unmet demand. Herein, for the first time, we embarked on proposing new mode of action herbicides by performing structure-based virtual screening targeting multiple LPOR binding sites, with determination further bioactivity lead series. The feasibility exploiting high...
The title compound, [Zn(C(8)H(4)O(4))](n), consists of one Zn(II) cation and benzene-1,2-dicarboxylate dianion (BDC(2-)) as the building unit. is four-coordinated by four carboxylate O atoms from dianionic BDC(2-) ligands in a distorted tetrahedral geometry. cations are linked to generate structure featuring two-dimensional zinc-carboxylate layers containing left- right-handed helical chains. stacked along direction. thermal stability compound has been studied.
Light-dependent protochlorophyllide oxidoreductase (LPOR) is a chlorophyll synthetase that catalyzes the reduction of (Pchlide) to chlorophyllide (Chlide) with indispensable roles in regulating photosynthesis processes. A recent study confirmed thylakoid lipids (TL) were able allosterically enhance modulator-induced LPOR activation. However, allosteric modulation mechanism by these compounds remains unclear. Herein, we integrated multiple computational approaches explore potential cavities...
IGPD is an essential metalloenzyme that catalyzes histidine biosynthesis. We found its C-terminus loop region has a vital role in determining enzyme activity but been hardly mentioned before. In this work, we focused on the dynamic feature and function of C-Loop Arabidopsis thaliana Saccharomyces cerevisiae (At_IGPD Sc_IGPD, respectively). Due to high flexibility region, performed total 3.4 μs accelerated molecular dynamics simulation enhance sampling. Inhibitor C348 At-IGPD exhibited...
Retracted.
To solve multi-objective decision making problems, many of the traditional models have been proposed. But these don't include all possible preferences maker. In this paper, we introduce concept weighted-objective similarity degree, and propose a new method decision-making based on degree. We obtain some related properties applications.
Information security can ensure an efficient application of classified computers. At present, in some computers, there exist problems and deficiencies the field information management. It is not conducive to control security. A network parallel computing system a network-based that has high potential resolve these issues. In recent years, with development cost-effective CPU high-speed technology, this gradually attracted attention people. Based on research distributed computing, paper...