Background/Objectives: Elevated body temperature is a well-established biomarker of infection, increased disease risk, and adverse health outcomes. However, the relationship between resting long-term survival in older individuals complex. Emerging evidence suggests that higher basal associated with reduced accelerated aging non-obese adults. This study aimed to compare temperatures across different age groups hospitalized Methods: Data were retrospectively collected from 367 physically...

Background/Objectives: The management of esophageal cancer (EC) remains a significant clinical challenge, particularly in optimizing therapeutic strategies for different stages and subgroups. This study assessed the impact preoperative radiochemotherapy (CRT) on staging identified subgroups whom definitive CRT (dCRT) may provide favorable alternative to surgery. Methods: Sixty-one patients with adenocarcinoma or squamous cell carcinoma were enrolled. Pre-treatment included computed...

Effective thermoregulation is crucial for maintaining homeostasis. Previous research has suggested a link between lower steady-state body temperature and longevity, particularly in physically healthy, nonobese older adults. However, the exact mechanisms behind this relationship remain unclear. Despite physiological insights gained from studies on temperature, limited attention been given to its potential role as biomarker of longevity healthy populations. This study aimed evaluate using...

Background/Objectives: Identifying reliable biomarkers for healthy aging and longevity is a fundamental challenge in research medical sciences. The neutrophil-to-lymphocyte ratio (NLR) readily measurable indicator of immune balance that reflects the interplay between innate activation adaptive suppression. Methods: This study examined NLR values 204 physically residents (98 men 106 women) stratified into four lifespan categories based on death certificates. Page’s test ordinal regression...

Abstract Over the decades, biogerontology has matured as a scientific discipline. Currently, number of theoretical frameworks are available to researchers when interpreting empirical data. Despite great progress that been made, comprehensive understanding biological processes shape ageing is lacking. Senescence dynamic, plastic and highly complex metaphenomenon whose aetiology remains unclear. The paucity information notwithstanding, some promote ‘anti-ageing’ drugs formulae every now again....

Effective communication and precise navigation within the intricacies of human body rely on robust anatomical terminology. Since its creation by Federative Committee Anatomical Terminology (FCAT), Terminologia Anatomica (TA 1998) has consistently served as benchmark in field. However, constant advancement knowledge requires regular revisions, updates, enhancements nomenclature to accommodate latest scientific discoveries. The recent adoption second edition 2019) International Federation...

For a very long time, ageing has been an insurmountable problem in biology. The collection of age-dependent changes that render individuals progressively more likely to die seemed be intractable labyrinth alterations and associations whose direct mechanisms ultimate explanations were too complex difficult understand. science always fraught with insuperable problems obstacles. In 1990, Zhores Medvedev presented list roughly 300 different hypotheses illustrate this remarkable complexity the...

Although not all authors agree that Terminologia Anatomica merits special attention, any type of scientific terminology should be clear, exact, logical, coherent and worldwide accepted. A precise definition every anatomical term is also crucial. New changes have recently been approved by the Federative International Programme for Anatomical Terminology as previous version required minor revisions. This situation offers an opportunity to take a closer look at these new interesting...

In 2016, the Federative International Programme for Anatomical Terminology tentatively approved updated and extended version of anatomical terminology that replaced previous Terminologia Anatomica (1998). This modern has already appeared in new editions leading atlases textbooks, including Netter’s Atlas Human Anatomy, even though it was originally available only as a draft final is different. We believe versions are important they can be powerful tool communication between anatomists other...

Early epidemiological studies demonstrated that short stature is associated with cardiovascular disease (CVD), diabetes, lower energy intake or food deprivation during growth, poor health, and increased all-cause mortality. Nevertheless, the links between adult height longevity become tenuous if certain confounders (e.g. BMI, SES, educational attainment, etc.) are allowed for. Furthermore, numerous have found like excess weight, tallness costly in terms of late ontogeny, shorter people tend...

Aging is currently stimulating intense interest of both researchers and the general public. In developed countries, average life expectancy has increased by roughly 30 years within last century, human senescence been delayed around a decade. Although aging arguably most familiar aspect biology, its proximate ultimate causes have not elucidated fully understood yet. Nowadays there are two main approaches to aging. These deterministic stochastic models. The theories constitute distinct group...

To date, numerous studies have reported that taller individuals are healthier and live longer. Nevertheless, the association between adult stature longevity involves conflicting findings. This study investigated whether Polish adults longer than their shorter counterparts. Data on declared height were available from 848,860 who died in years 2004–2008 Poland. allow for cohort effect, Z -values generated. Separately both sexes, Pearson's r coefficients of correlation calculated. Subsequently,...

The connection between the rate of height loss in older people and their general health status has been well documented medical literature. Our study was aimed at furthering characterization this interrelationship context indices mortality a hospitalized population Polish adults. Data were collated from literature review longitudinal aging carried out which followed 142 physically healthy inmates, including 68 men 74 women, for least 25 years age 45 onwards. Moreover, cross-sectional data...

Longitudinal studies of aging concerning individuals with comparable lifestyle, diet, health profile, socioeconomic status, and income remain extraordinarily rare. The purposes our ongoing project are as follows: (i) to collect extensive data on biological medical aspects in the Polish population, (ii) determine factors affecting rate course aging, (iii) understand how unfolds a dynamic malleable process ontogeny, (iv) find novel predictors longevity. Our investigation followed 142...

As human life expectancy continues to rise, becoming a pressing global concern, it brings into focus the underlying mechanisms of aging. The increasing lifespan has led growing elderly population grappling with age-related diseases (ARDs), which strains healthcare systems and economies worldwide. While senescence was once regarded as an immutable inexorable phenomenon, impervious interventions, emerging field geroscience now offers innovative approaches aging, holding promise extending...

Surgical treatment for serious malocclusions and fractures of the organ mastication is a golden standard in medicine. Procedures performed on mandible require detailed knowledge anatomy organ. Antegonial notching constitutes technical challenge surgeons. Therefore, anatomical description this structure, which subject paper, essential.We analysed 251 human Caucasian mandibles identified sex took measurements all sections describing mandibular antegonial notch. Depending proportion between we...

Bilirubin is a potent antioxidant and an important anti-inflammatory factor. Therefore, there has been increasing focus on serum bilirubin as negative risk factor of cardiovascular mortality in men indicator improved survival both sexes, but the direct mechanisms these links causes sex differences are not well understood. Moreover, evidence from longitudinal studies effects longevity limited. In this study, we retrospectively analyzed two groups older adults to explore age-dependent changes...

In 2019, the updated and extended version of Terminologia Anatomica was published by Federative International Programme for Anatomical Terminology (FIPAT). This new edition uses more precise adequate anatomical names compared to its predecessors. Nevertheless, numerous terms have been modified, which poses a challenge those who prefer traditional names, i.e. medical students, teachers, clinicians their instructors. Therefore, there is need popularise this terminology explain these recent...