A5101648128- Network Security and Intrusion Detection
- Advanced Malware Detection Techniques
- Information and Cyber Security
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pancreatic and Hepatic Oncology Research
- Cancer Cells and Metastasis
- Epigenetics and DNA Methylation
- Renal cell carcinoma treatment
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Spam and Phishing Detection
- Chemokine receptors and signaling
- Glioma Diagnosis and Treatment
- Advanced Computational Techniques and Applications
- Hedgehog Signaling Pathway Studies
- Genomics, phytochemicals, and oxidative stress
- Cancer Immunotherapy and Biomarkers
- Urinary and Genital Oncology Studies
- Catalytic Processes in Materials Science
- Digital Rights Management and Security
- Peer-to-Peer Network Technologies
- Authorship Attribution and Profiling
- Artificial Intelligence in Law
Beijing University of Posts and Telecommunications
2023-2024
East China University of Science and Technology
2022
China Information Technology Security Evaluation Center
2019-2022
Chinese Academy of Sciences
2015-2022
Xinxiang Medical University
2020-2022
Research Institute of Petroleum Exploration and Development
2021
People’s Hospital of Rizhao
2008-2020
Jining Medical University
2018
Institute of Information Engineering
2015-2018
Guangzhou University
2018
Abstract NADPH provides the reducing power for decomposition of reactive oxygen species (ROS), making it an indispensable part during ROS defense. It remains uncertain, however, if living cells respond to challenge with elevated intracellular level or a more complex NADPH-mediated manner. Herein, we employed model fungus Aspergillus nidulans probe this issue. A conditional expression glucose-6-phosphate dehydrogenase (G6PD)-strain was constructed manipulate levels. As expected, turning down...
Abstract Sulforaphane (SFN), an active compound in cruciferous vegetables, has been characterized by its antiproliferative capacity. We investigated the role and molecular mechanism through which SFN regulates proliferation self-renewal of lung cancer stem cells. CD133 + cells were isolated with MACs from A549 H460 In this study, we found that inhibited simultaneously. Meanwhile, mRNA protein expressions Shh, Smo, Gli1 PHC3 highly activated Compared siRNA-control group, Knock-down Shh cells,...
Osimertinib is a novel and irreversible epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) targeting
Security measurement matters to every stakeholder in network security. It provides security practitioners the exact awareness. However, most of works are not applicable unknown threat. What is more, existing efforts on metric mainly focus ease certain attack from a theoretical point view, ignoring “likelihood exploitation.” To help administrator have better understanding, we analyze behavior attackers who exploit zero-day vulnerabilities and predict their timing. Based prediction, propose...
Recently, mobile technology has become closely linked with our daily activities. Smartphones are used for multiple personal tasks involving private information, such as communication, healthcare, and banking. Therefore, there is a high demand user-friendly authentication methods that prevent unauthorized access to sensitive information. This paper proposes novel feature representation tactic continuous named Multiple Channels Biological Graph (MCBG). Unlike conventional techniques, MCBG...
Objective To evaluate the effect of gemcitabine plus three dimensional conformal radiotherapy on patients with locally acvanced pancreatic cancer. Methods Fifty-four advanced cancer from April 2003 to June 2005 were enrolled, one 25 treated (experiment group), other 29 only (control group). Results The general remission rate was 69.6% in experiment group and 39.3% control group, showing a significant statistical difference between two groups(P＜0.05)). There no groups metastases (43.5% vs...
Objective To evaluate the clinical efficacy and adverse reactions of S-1 chemotherapy plus high-low oxygen radiotherapy synchronously in treatment patients with locally advanced pancreatic cancer. Methods Sixty-four cancer Rizhao People's Hospital Affiliated Qingdao University from January 2013 to October 2015 were randomly divided into study group control by using envelope method, which was treated oral administration radiation intravenous gemcitabine chemotherapy. The efficiency,...
In order to fully understand the overall security situation of network system and control risks, it is necessary shift assessment from qualitative quantitative. The existing work has problems such as incomplete considerations, inconsistent measurement standards, unspecified implementation plans. fundamental reason lack a comprehensive indicator system. Based on information latitude longitude line theory Academician Fang Binxing, this paper proposes two-dimensional framework system, mines...
Objective To investigate the regulatory effects and mechanism of mannan-binding lectin (MBL) on adipogenic differentiation 3T3-L1 preadipocytes. Methods 3T3-L1 preadipocytes were induced to differentiate into adipocytes in vitro, stimulated with different concentrations MBL (0, 1, 10, 20 μg/ml). Firstly, changes cell proliferation ability detected by CCK-8. Then lipid accumulation was analyzed Oil red O staining intracellular triglyceride content determination. Further, expression...
In recent years, the number of users in High-Speed Rail (HSR) networks has been increasing dramatically, which further leads to dramatic increment service data carried by HSR networks. However, extremely high mobility high-speed train brought great challenges transmit with quality and security. At first, current researches on transmission mainly uses single base station model. That is, each mobile is only able communicate one station. Although this analysis method relatively viable simple,...
OBJECTIVE To investigate the effect of sulforaphane (SFN) on G2/M phase arrest acute myeloid leukemia cells and its molecular mechanism. METHODS KG1a KG1cells were treated by different concentrations SFN for 48 h. Flow cytometry (FCM) was used to analyze distribution cell cycle. High-throughput sequencing detect expression cycle related genes in cells. The mRNA P53, P21, CDC2 CyclinB1 detected qPCR. protein CDC2, P-CDC2 Western blot. RESULTS Cells increased from 11.9% 54.0% 18.5% 83.3% KG1...
To evaluate the expression of epidermal growth factor receptor (EGFR) mutation specific antibodies in invasive lung adenocarcinomas, and their sensitivity, specificity, as well relationship to histological subtypes.Immunostaining with EGFR mutation-specific antibodies, del E746-A750 exon 19 L858R 21, was performed tissue microarrays 884 cases resection specimens study between immunophenotypes morphologic subtypes. The sensitivity specificity stains were compared gene mutations detected by...