Lucio Simonella

ORCID: 0000-0002-7027-327X
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About
Contact & Profiles
Research Areas
  • Immune Response and Inflammation
  • Inflammatory mediators and NSAID effects
  • Cancer, Stress, Anesthesia, and Immune Response
  • Aeolian processes and effects
  • Geology and Paleoclimatology Research
  • Immune cells in cancer
  • Marine and coastal ecosystems
  • Immunotherapy and Immune Responses
  • Atmospheric chemistry and aerosols
  • Geochemistry and Elemental Analysis
  • Eicosanoids and Hypertension Pharmacology
  • Atmospheric aerosols and clouds
  • Geological and Tectonic Studies in Latin America
  • Enzyme Structure and Function
  • Paleontology and Stratigraphy of Fossils
  • Advanced Proteomics Techniques and Applications
  • Heavy metals in environment
  • Biotin and Related Studies

Universidad Nacional de Córdoba
2007-2023

Consejo Nacional de Investigaciones Científicas y Técnicas
2007-2023

Research Center on Earth Sciences
2013-2015

Abstract This study provides a detailed description of the sources, transport, dispersion, and deposition two major dust events originating from high‐altitude subtropical Puna‐Altiplano Plateau (15–26°S; 65–69°W) in South America. A long severe drought provided right conditions for onset both July 2009 2010. Dust was transported SE deposited over Pampas region observed to continue Atlantic Ocean. monitoring stations located downwind recorded events, samples were characterized through...

10.1002/jgrd.50036 article EN Journal of Geophysical Research Atmospheres 2013-04-22

Abstract Although an eruption of information on the role Toll-like receptor 4 (TLR4), main for bacterial lipopolysaccharide, in activating macrophages and dendritic cells has emerged, very little is known about TLR4 present epithelial from sterile environments like tumors. The goal this work was to investigate consequences activation tumor two different animal models cancer: Dunning rat prostate cancer B16 murine melanoma models. We show that (a) signaling cell lines vitro modifies outgrowth...

10.1158/0008-5472.can-07-0079 article EN Cancer Research 2007-11-01

Abstract Patagonia, due to its geographic position and the dominance of westerly winds, is a key area that contributes supply nutrients Southern Ocean, both through mineral dust periodic deposits volcanic ash. Here we evaluate characteristics Fe dissolved (into soluble colloidal species) from ash for three recent southern Andes eruptions having contrasting features chemical compositions. Contact between cloud waters (wet deposition) end‐members andesitic (Hudson volcano) rhyolitic (Chaitén...

10.1002/2015gb005177 article EN Global Biogeochemical Cycles 2015-07-14

Abstract Mineral aerosols may affect global climate indirectly by enhancing net primary productivity (NPP) upon deposition to the oceans and associated atmosphere‐to‐ocean CO 2 flux. This mechanism is hypothesized have contributed significantly last interglacial‐to‐glacial climatic transition. However, dust‐NPP connection remains contentious for present‐day system. We analyze impact of southernmost Patagonian dust emissions on southwestern Atlantic Ocean continental shelf proximal open ocean...

10.1029/2020jg006073 article EN Journal of Geophysical Research Biogeosciences 2020-12-01

Supplementary Figure 1 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370081 preprint EN cc-by 2023-03-30

Supplementary Figure 2 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370078 preprint EN cc-by 2023-03-30

Supplementary Figure 2 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370078.v1 preprint EN cc-by 2023-03-30

Supplementary Legends 1-2 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370075.v1 preprint EN cc-by 2023-03-30

<div>Abstract<p>Although an eruption of information on the role Toll-like receptor 4 (TLR4), main for bacterial lipopolysaccharide, in activating macrophages and dendritic cells has emerged, very little is known about TLR4 present epithelial from sterile environments like tumors. The goal this work was to investigate consequences activation tumor two different animal models cancer: Dunning rat prostate cancer B16 murine melanoma models. We show that (<i>a</i>)...

10.1158/0008-5472.c.6496259 preprint EN 2023-03-30

Supplementary Figure 1 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370081.v1 preprint EN cc-by 2023-03-30

Supplementary Legends 1-2 from Activation of Toll-like Receptor 4 on Tumor Cells <i>In vitro</i> Inhibits Subsequent Growth vivo</i>

10.1158/0008-5472.22370075 preprint EN cc-by 2023-03-30

<div>Abstract<p>Although an eruption of information on the role Toll-like receptor 4 (TLR4), main for bacterial lipopolysaccharide, in activating macrophages and dendritic cells has emerged, very little is known about TLR4 present epithelial from sterile environments like tumors. The goal this work was to investigate consequences activation tumor two different animal models cancer: Dunning rat prostate cancer B16 murine melanoma models. We show that (<i>a</i>)...

10.1158/0008-5472.c.6496259.v1 preprint EN 2023-03-30

<p>The magnitude of the climate forcing associated with mineral dust aerosols remains uncertain, due in part to a lack direct observations on source areas. While modeling and satellite studies provide spatially extensive constraints, these must be supported by surface-validating, situ monitoring. Our study focuses Patagonia, main southern oceans (>45ºS), region low biological productivity potentially susceptible increased micronutrient fertilization through...

10.5194/egusphere-egu21-156 article EN 2021-03-03
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