A5085620047- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Bone health and treatments
- Cancer Diagnosis and Treatment
- Intellectual Property and Patents
- Reproductive Biology and Fertility
- Estrogen and related hormone effects
- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Ovarian function and disorders
- Bone health and osteoporosis research
- Food composition and properties
- Breast Lesions and Carcinomas
- Ovarian cancer diagnosis and treatment
- Biofuel production and bioconversion
- Cancer, Lipids, and Metabolism
- Advanced Breast Cancer Therapies
- Technology Assessment and Management
- Gastric Cancer Management and Outcomes
- Vestibular and auditory disorders
- Advances in Oncology and Radiotherapy
- Amino Acid Enzymes and Metabolism
- Cancer-related molecular mechanisms research
- Digital Radiography and Breast Imaging
The University of Western Australia
2015-2024
Fiona Stanley Hospital
2016-2024
University of Cambridge
2024
Cancer Research UK
2024
Cambridge University Hospitals NHS Foundation Trust
2024
Cancer Research UK Cambridge Center
2024
Flinders Medical Centre
2010-2016
Flinders University
2016
Royal Perth Hospital
2013-2015
Calvary Hospital
2012-2014
The prognostic significance of various systemic inflammation-based markers has been explored in different cancers. These can be used to assist with decision-making oncology clinics.The aim this study was investigate the three factors: neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR) and modified Glasgow Prognostic Score (mGPS) patients advanced pancreatic cancer.Data were collected retrospectively for cancer treated between 1 January 2008 31 December 2012 at Royal Perth Hospital....
Abstract Background The incidence of cancer diagnosed during pregnancy is increasing. Data relating to investigation and management, as well maternal foetal outcomes lacking in a United Kingdom (UK) population. Methods In this retrospective study we report data from 119 patients with 14 centres the UK across five-year period (2016-2020). Results Median age at diagnosis was 33 years, breast, skin haematological most common primary sites. majority cases were new diagnoses (109 patients,...
An enzyme is described which catalyzes the release of soluble β-glucan from insoluble barley endosperm cell walls. This increases in activity throughout malting. It has been partially purified and found to behave same way as an acidic carboxypeptidase on isoelectric focusing its sensitivity inhibitors activators heating. The importance solubilizing malting mashing discussed. improved method for determination described.
Significant β-glucanolysis takes place during mashing and is catalysed by a β-glucanase which specific to mixed-linkage β-glucans. The enzyme develops the germination of barley, but rapidly extensively destroyed in kilning. Partially-purified preparations are protected from denaturation heat if their solutions adjusted pH 4 or bovine serum albumin added. However most effective stabiliser reduced glutathione. Oligosaccharides containing three four glucosyl units produced action they further...
Crude cellulase preparations from Trichoderma reesei, freed of amyloglucosidase by heating, will completely hydrolyse barley β-glucan to glucose. Apparent non-quantitative recovery glucose is due its adsorption the high levels protein present. Methods are given for measurement total and water-soluble β-glucan. Dehusking does not lower amount which measured.
An assay for the routine determination of β-glucanase by a gel diffusion technique has been established. The method many features which make it preferable to viscometric procedure currently employed.
Skeletal metastases present a major challenge for clinicians, representing an advanced and typically incurable stage of cancer. Bone is also the most common location metastatic breast carcinoma, with skeletal lesions identified in over 80% patients Preclinical models have demonstrated ability mechanical stimulation to suppress tumour formation promote preservation at bone sites osteolytic lesions, generating modulatory interference tumour-driven remodelling. studies anti-cancer effects...
Abstract Objective To investigate whether any survival differences existed between advanced cancer patients treated in metropolitan P erth and those regional W estern A ustralia ( WA ). Design Retrospective study. Setting Advanced through medical oncology clinics at R oyal H ospital centres K algoorlie, lbany, G eraldton N ortham). Participants Patients diagnosed with melanoma, breast, colorectal, gastro‐oesophageal, prostate, lung pancreatic cancers 1 J anuary 2007 31 D ecember 2011....
Aromatase inhibitors (AIs) are associated with reduction in bone mineral density (BMD). The use of strengthening agents zoledronic acid and denosumab improved breast cancer outcomes for post-menopausal patients treated AIs. This study investigates whether change BMD AI therapy is recurrence.
Nanotechnology is predicted to create the Sixth Kondratieff period following 'age of information'. It represents a new revolutionary approach in fundamental research moving from macrocentric nanocentric system. expected stimulate one trillion dollars production involving about two million workers next ten 15 years. More than 40 countries now have specific nanotechnology funding programs with common goal finding greater uses for emerging technologies and enacting measures encourage...
Nanotechnology is predicted to create the Sixth Kondratieff period following "Age of Information". It represents a new revolutionary approach in fundamental research moving from macrocentric nanocentric system. expected stimulate 1 trillion dollars production involving about 2 million workers next 10 15 years. More than 40 countries now have specific nanotechnology funding programs with common goal finding greater uses for emerging technologies and enacting measures encourage...
Goserelin, a form of medical ovarian suppression, is an effective treatment for pre-menopausal women with breast cancer (PMBC). Meta-analysis data showed that similar efficacy achieved suppression and non-pharmacological (NPOS) - oophorectomy or irradiation. The acceptance rate NPOS remains low.This study explored the reported toxicities PMBC their preferred method whilst on goserelin.A postal survey consisting 22 study-specific questions was sent to who received goserelin at Flinders...
Aim To investigate the management and cancer outcomes of liver transplant recipients. Method An audit all recipients from a single center January 1991 to March 2010. Data were obtained case notes, registry clinical databases. Results 198 identified 49 (25%) confirmed as having post-transplantation malignancies. Of these 32 (16%) patients developed skin malignancies 17 (9%) post-transplant non-skin All had local involvement only none with nodal or distant metastases. managed treatment. those...
Technology intelligence using techniques such as data mining or patent analyses is not a new concept in the management of technology. Nevertheless, there lack useful, user-friendly that incorporate quantitative and expert judgements technology forecasting, especially if application targets medical electronic device industry. This study aims to develop model integrates from variety sources roadmap for emerging technologies.
The presence of an intraductal component together with invasive carcinoma is known to be associated a higher rate local recurrence. results reviewing 250 resected surgical specimens from patients breast cancer are reported. Two-hundred and fifty mastectomy were retrospectively analysed in order determine components within the primary tumour as well additional foci. In addition carcinoma, ductal situ (DCIS) varying extent was identified 127 instances. marginal 27.6% cases, extensive 61.4%,...
Differences and interactions between the adrenal parathyroid were found in studies of electrolyte excretion control, adx, ptx adx-ptx rats before during administration aldosterone, PTE both hormones. The increased urine Na CI decreased K compared to other groups was a new, unexplained finding. Aldosterone caused decrease all CI, PO4, except rats, stool Ca, rise groups. PTE, contrast, an increase PO4 Ca combination two hormones, not previously studied, same but much higher values than with...
Abstract We describe the case of a patient with Rett syndrome, syndrome characterized by progressive infant encephalopathy, developmental delay, dementia, autism, ataxia, microcephaly, spastic paraparesis, and autonomic neuropathy constipation. At colonoscopy, multiple foci tiny white, sessile, polypoid lesions were seen throughout colon rectum, mimicking appearances small hyperplastic or adenomatous polyps, associated generalized melanosis coli. This is first to our knowledge describing...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study